Last updated: May 29, 2026

Application No. 18/317,352

BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE

Final Rejection

Filed

May 15, 2023

Priority

Jun 09, 2020 — provisional 63/036,811 +1 more

Examiner

KIFLE, BRUCK

Art Unit

1624

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Prelude Therapeutics Incorporated

OA Round

2 (Final)

Interview Optional

— +15.9% interview lift. Examiner has a relatively high allowance rate (79%); +15.9% interview lift. A written response may suffice.

Based on 1718 resolved cases, 2023–2026

Examiner Intelligence

KIFLE, BRUCK View full profile →

Grants 79% — above average

Career Allowance Rate

1360 granted / 1718 resolved

+19.2% vs TC avg

Strong +16% interview lift

Without

With

+15.9%

Interview Lift

resolved cases with interview

Fast prosecutor

1y 9m

Avg Prosecution

30 currently pending

Career history

1745

Total Applications

across all art units

Statute-Specific Performance

§101

3.8%

-36.2% vs TC avg

§103

16.9%

-23.1% vs TC avg

§102

10.0%

-30.0% vs TC avg

§112

50.9%

+10.9% vs TC avg

Black line = Tech Center average estimate • Based on career data from 1718 resolved cases

Prosecution Timeline

May 15, 2023

Application Filed

Sep 17, 2025

Non-Final Rejection mailed

Mar 17, 2026

Response Filed

Apr 01, 2026

Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

16/972,670

Patent 12624026

INHIBITORS OF SARM1

5y 5m to grant Granted May 12, 2026

18/253,887

Patent 12623994

METHOD OF PREPARING HETEROGENEOUS LINEAR CARBONATE USING CATALYST HAVING EXCELLENT SOLUBILITY

2y 11m to grant Granted May 12, 2026

18/348,763

Patent 12617761

PROCESS FOR PRODUCING HEXAHYDRO 1,3,5-TRINITRO-1,3,5-TRIAZINE AND OCTAHYDRO-1,3,5,7-TETRANITRO-1,3,5,7-TETRAZOCINE

2y 10m to grant Granted May 05, 2026

17/785,941

Patent 12612371

SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF

3y 10m to grant Granted Apr 28, 2026

18/254,321

Patent 12604894

SOLID PESTICIDAL FORMULATION

2y 11m to grant Granted Apr 21, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

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Prosecution Projections

3-4

Expected OA Rounds

79%

Grant Probability

95%

With Interview (+15.9%)

1y 9m (~0m remaining)

Median Time to Grant

Moderate

PTA Risk

Based on 1718 resolved cases by this examiner. Grant probability derived from career allowance rate.