Prosecution Insights
Last updated: July 17, 2026
Application No. 18/329,245

CASPASE-3-TRIGGERED MOLECULAR SELF-ASSEMBLING PET PROBES AND USES THEREOF

Non-Final OA
Filed
Jun 05, 2023
Priority
Sep 14, 2018 — provisional 62/731,469 +2 more
Examiner
JONES, DAMERON LEVEST
Art Unit
1618
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
The Board of Trustees of the Leland Stanford Junior University
OA Round
2 (Non-Final)
68%
Grant Probability
Favorable
2-3
OA Rounds
4m
Est. Remaining
99%
With Interview

Examiner Intelligence

Grants 68% — above average
68%
Career Allowance Rate
730 granted / 1079 resolved
+7.7% vs TC avg
Strong +31% interview lift
Without
With
+31.4%
Interview Lift
resolved cases with interview
Typical timeline
3y 5m
Avg Prosecution
40 currently pending
Career history
1122
Total Applications
across all art units

Statute-Specific Performance

§101
0.5%
-39.5% vs TC avg
§103
41.7%
+1.7% vs TC avg
§102
8.0%
-32.0% vs TC avg
§112
37.7%
-2.3% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1079 resolved cases

Prosecution Timeline

Jun 05, 2023
Application Filed
Feb 20, 2025
Response Filed
Sep 12, 2025
Non-Final Rejection mailed
Dec 11, 2025
Response Filed
Dec 12, 2025
Response Filed
Jun 30, 2026
Request for Continued Examination
Jul 01, 2026
Response after Non-Final Action
Jul 14, 2026
Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12673083
TREM-1 INHIBITORS FOR THE TREATMENT OF VASO-OCCLUSIONS AND TISSUE INJURIES IN PATIENTS SUFFERING FROM SICKLE CELL DISEASE
4y 1m to grant Granted Jul 07, 2026
Patent 12653913
HER2 BINDERS
3y 3m to grant Granted Jun 16, 2026
Patent 12642883
AN INJECTABLE AND IN-SITU CROSSLINKING HYDROGEL FOR ENDOVASCULAR EMBOLIZATION
3y 8m to grant Granted Jun 02, 2026
Patent 12625147
NOVEL MOLECULAR TOOLS TO VISUALIZE AND TARGET THE CARDIAC CONDUCTION SYSTEM (CCS)
4y 4m to grant Granted May 12, 2026
Patent 12616759
USES OF LABELED HSP90 INHIBITORS
3y 3m to grant Granted May 05, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

2-3
Expected OA Rounds
68%
Grant Probability
99%
With Interview (+31.4%)
3y 5m (~4m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 1079 resolved cases by this examiner. Grant probability derived from career allowance rate.

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