Prosecution Insights
Last updated: April 19, 2026
Application No. 18/360,758

SYSTEMS AND METHODS FOR DELIVERING MICRODOSES OF MEDICATION

Non-Final OA §103
Filed
Jul 27, 2023
Examiner
SCHMIDT, EMILY LOUISE
Art Unit
3783
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Tandem Diabetes Care Switzerland Sàrl
OA Round
5 (Non-Final)
59%
Grant Probability
Moderate
5-6
OA Rounds
3y 5m
To Grant
95%
With Interview

Examiner Intelligence

Grants 59% of resolved cases
59%
Career Allow Rate
581 granted / 992 resolved
-11.4% vs TC avg
Strong +36% interview lift
Without
With
+36.0%
Interview Lift
resolved cases with interview
Typical timeline
3y 5m
Avg Prosecution
77 currently pending
Career history
1069
Total Applications
across all art units

Statute-Specific Performance

§101
0.6%
-39.4% vs TC avg
§103
48.9%
+8.9% vs TC avg
§102
25.8%
-14.2% vs TC avg
§112
18.7%
-21.3% vs TC avg
Black line = Tech Center average estimate • Based on career data from 992 resolved cases

Office Action

§103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Continued Examination Under 37 CFR 1.114 A request for continued examination under 37 CFR 1.114, including the fee set forth in 37 CFR 1.17(e), was filed in this application after final rejection. Since this application is eligible for continued examination under 37 CFR 1.114, and the fee set forth in 37 CFR 1.17(e) has been timely paid, the finality of the previous Office action has been withdrawn pursuant to 37 CFR 1.114. Applicant's submission filed on December 3, 2025 has been entered. Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. Claim(s) 21, 28, and 30 is/are rejected under 35 U.S.C. 103 as being unpatentable over Vazquez et al. (US 2015/0265768 A1) in view of Dhami (US 2015/0184648 A1). With regard to claim 21, Vazquez et al. teach a medication infusion device comprising: a patch pump configured to be removably adhered to a wearer's skin (Fig. 2 member 100, adhesive 114) for delivering doses of medication from a cartridge (Fig. 3 cartridge 116) through a transcutaneous portion (Fig. 3 160), the patch pump comprising a pump housing (Fig. 1 housing 106); a pump motor disposed within the pump housing (Fig. 9 member 138), the pump motor configured to pump the medication towards the transcutaneous portion ([0064]); a sensor configured to sense a parameter ([0056], [0065], [0079], [0082], [0097], [0100], Fig. 18 406 and 408); a vibration motor separate (Fig. 9 member 132 coupled via device structure/operation) from and coupled with the pump motor; and a controller operatively coupled to the sensor and the vibration motor, the controller configured to cause the vibration motor to vibrate to alert the wearer based at least in part on the parameter sensed by the sensor ([0066], [0085], [0087], [0135], Fig. 18 processor 420, couple to the sensors and vibration motor 410 which provides alerts which can be generated, for example, in a scenario when the cartridge sensor has not detected a cartridge); a circuit board including the controller and the motor driver thereon, the circuit board configured as a flexible substrate, wherein the circuit board has a plurality of sections having electrical components thereon, each of the plurality of sections connected by flexible electrical connections (see [0064], [0066], Figs. 8-10 flexible substrate 130. As combined the motor driver would also be included with the circuit board. As the entirety of the substrate is flexible the connections would necessarily be flexible, there is more than one component on such a substrate). Vazquez et al. teach the substrate to be flexible but do not explicitly show it bent or folded around the motors. However, Dhami teaches a circuit board which is flexible between sections so it may conform and fold to fit the enclosure of a pump and provide functionality proximate a point of use (Fig. 9, [0129], [0133]-[0136]). It would have been obvious to a person having ordinary skill in the art before the effective filing date of the claimed invention that the substrate would in some way bend and fold around the motors in Vazquez et al. as Dhami teaches this is beneficial to conform to the pump enclosure and allow components to be proximate their point of use. Further as the substrate of Vazquez et al. is entirely flexible this necessarily allows the substrate to conform around components for space and allows flexion for electrical attachments. With regard to claim 28, Vazquez et al. teach sensors may be used to detect occlusions based on a compared change in the rate ([0098]). As rejected above the circuit board is folded and the sensor would necessarily be adjacent the dosing pathway as no specific distance is recited. Such a sensor would necessarily be disposed on a section of the circuit board. With regard to claim 30, Vazquez et al. teach a micro pump 136 for dosing fluid ([0136]) status sensors 408 monitor the delivery of the pump ([0082], [0097]). As rejected above the circuit board is folded and the sensor would necessarily be adjacent the microdosing system as no specific distance is recited. Such a sensor would necessarily be disposed on a section of the circuit board. Claim(s) 29 is/are rejected under 35 U.S.C. 103 as being unpatentable over Vazquez et al. (US 2015/0265768 A1) and Dhami (US 2015/0184648 A1) as applied to claim 21 above, and further in view of Yavorsky et al. (US 2016/0369790 A1). With regard to claim 29, Vazquez et al. teach providing a sensor to determine the fluid level based on the plunger or piston location ([099], [0100]) but does not disclose a pressure sensor. However, Yavorsky et al. teach a patch pump and determining if a reservoir is empty based on pressure to alert the user ([0234]). It would have been obvious to a person having ordinary skill in the art before the effective filing date of the claimed invention to measure pressure to provide an alert to the user in Vazquez et al. as Yavorsky et al. teach this is beneficial for determining if the cartridge is empty. As rejected above the circuit board is folded and the sensor would necessarily be adjacent the pushing mechanism as no specific distance is recited. Such a sensor would necessarily be disposed on a section of the circuit board. Claim(s) 31 is/are rejected under 35 U.S.C. 103 as being unpatentable over Vazquez et al. (US 2015/0265768 A1) and Dhami (US 2015/0184648 A1) as applied to claim 21 above, and further in view of Newberry et al. (US 2017/0014572 A1). With regard to claim 31, Vazquez et al. teach a device substantially as claimed. Vazquez et al. do not disclose a photoplethysmographic sensor. However, Newberry et al. teach a patch pump which includes a photoplethysmographic sensor to monitor a user heart rate and other physiologic parameters which are used to compare to threshold values to determine delivery and provide alerts (see at least [0035], [0076]-[0078], [0144]). It would have been obvious to a person having ordinary skill in the art before the effective filing date of the claimed invention to alert the user in Vazquez et al. when values detected by the photoplethysmographic sensor fall outside threshold values as in Newberry et al. as this would be beneficial for allowing the user to seek medical attention if necessary. As rejected above the circuit board is folded and the sensor would necessarily be placed proximate to its function, a photoplethysmographic sensor would need to face the skin to work. Such a sensor would necessarily be disposed on a section of the circuit board. Claim(s) 32 is/are rejected under 35 U.S.C. 103 as being unpatentable over Vazquez et al. (US 2015/0265768 A1) and Dhami (US 2015/0184648 A1) as applied to claim 21 above, and further in view of Caspers (US 2017/0259015 A1). With regard to claim 32, Vazquez et al. teach a device substantially as claimed. Vazquez et al. teach the device is adhered to the skin ([0049]) but do not disclose a skin detector. However, Caspers teaches using skin contact sensors to alert the user if the device becomes detached and stop injection to ensure safety (abstract). It would have been obvious to a person having ordinary skill in the art before the effective filing date of the claimed invention to use a skin contact sensor in Vazquez et al. as Caspers teaches this is beneficial to enhance safety as it prevents delivery if the device is not attached. As rejected above the circuit board is folded and the sensor would necessarily be placed proximate to its function, a skin contact sensor would need to face the skin to work. Such a sensor would necessarily be disposed on a section of the circuit board. Claim(s) 22-25 is/are rejected under 35 U.S.C. 103 as being unpatentable over Vazquez et al. (US 2015/0265768 A1) in view of Chiu et al. (US 2020/0384197 A1). With regard to claims 22-25, Vazquez et al. teach a medication infusion device comprising: a patch pump configured to be removably adhered to a wearer's skin (Fig. 2 member 100, adhesive 114) for delivering doses of medication from a cartridge (Fig. 3 cartridge 116) through a transcutaneous portion (Fig. 3 160), the patch pump comprising a pump housing (Fig. 1 housing 106); a pump motor disposed within the pump housing (Fig. 9 member 138), the pump motor configured to pump the medication towards the transcutaneous portion ([0064]); a sensor configured to sense a parameter ([0056], [0065], [0079], [0082], [0097], [0100], Fig. 18 406 and 408); a vibration motor separate (Fig. 9 member 132 coupled via device structure/operation) from and coupled with the pump motor; and a controller operatively coupled to the sensor and the vibration motor, the controller configured to cause the vibration motor to vibrate to alert the wearer based at least in part on the parameter sensed by the sensor ([0066], [0085], [0087], [0135], Fig. 18 processor 420, couple to the sensors and vibration motor 410 which provides alerts which can be generated, for example, in a scenario when the cartridge sensor has not detected a cartridge). Vazquez et al. teach the housing is made of a plastic shell ([0064]) and protects the components from water ([0066]) but do not explicitly disclose a separate dry and wet zone. However, Chiu et al. teach using an o-ring between the fluid reservoir compartment and the pump compartment to prevent the ingress of fluid ([0212]). It would have been obvious to a person having ordinary skill in the art before the effective filing date of the claimed invention to use a seal between the fluid and electronic pump components of Vazquez et al. as Chiu et al. teach this is beneficial for preventing the ingress of fluid into where the pump is located. Claim(s) 26 and 27 is/are rejected under 35 U.S.C. 103 as being unpatentable over Vazquez et al. (US 2015/0265768 A1) and Chiu et al. (US 2020/0384197 A1) as applied to claim 25 above, and further in view of Wenger et al. (US 2009/0156990 A1). With regard to claims 26 and 27, Vazquez et al. teach a device substantially as claimed. Vazquez et al. do not disclose one or more vents with breathable fabric. However, Wenger et al. teach using a Gore-tex vent over an electronic compartment with a battery to provide air to the power source without allowing moisture in ([0079]). It would have been obvious to a person having ordinary skill in the art before the effective filing date of the claimed invention to use a vent in Vazquez et al. as Wenger et al. teach this is beneficial to allow air to reach the battery without allowing moisture. Response to Arguments Applicant’s arguments with respect to the claim(s) have been considered but are moot because the new ground of rejection does not rely on any reference applied in the prior rejection of record for any teaching or matter specifically challenged in the argument. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to EMILY L SCHMIDT whose telephone number is (571)270-3648. The examiner can normally be reached Monday through Thursday 7:00 AM to 4:30 PM. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Kevin Sirmons can be reached at 571-272-4965. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /EMILY L SCHMIDT/ Primary Examiner, Art Unit 3783
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Prosecution Timeline

Jul 27, 2023
Application Filed
Aug 09, 2024
Non-Final Rejection — §103
Nov 14, 2024
Response Filed
Dec 02, 2024
Final Rejection — §103
Feb 05, 2025
Response after Non-Final Action
Feb 18, 2025
Request for Continued Examination
Feb 19, 2025
Response after Non-Final Action
May 16, 2025
Non-Final Rejection — §103
Aug 20, 2025
Response Filed
Sep 08, 2025
Final Rejection — §103
Oct 30, 2025
Response after Non-Final Action
Dec 03, 2025
Request for Continued Examination
Dec 16, 2025
Response after Non-Final Action
Mar 20, 2026
Non-Final Rejection — §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

5-6
Expected OA Rounds
59%
Grant Probability
95%
With Interview (+36.0%)
3y 5m
Median Time to Grant
High
PTA Risk
Based on 992 resolved cases by this examiner. Grant probability derived from career allow rate.

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