Prosecution Insights
Last updated: October 01, 2026
Application No. 18/363,429

NERVE AGENT DECONTAMINATING AGENTS

Non-Final OA §102
Filed
Aug 01, 2023
Priority
Aug 01, 2022 — provisional 63/394,055
Examiner
SZNAIDMAN, MARCOS L
Art Unit
1628
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
The Curators of the University of Missouri
OA Round
1 (Non-Final)
37%
Grant Probability
At Risk
1-2
OA Rounds
4m
Est. Remaining
54%
With Interview

Examiner Intelligence

Grants only 37% of cases
37%
Career Allowance Rate
475 granted / 1273 resolved
-22.7% vs TC avg
Strong +16% interview lift
Without
With
+16.2%
Interview Lift
resolved cases with interview
Typical timeline
3y 6m
Avg Prosecution
80 currently pending
Career history
1346
Total Applications
across all art units

Statute-Specific Performance

§101
1.8%
-38.2% vs TC avg
§103
38.4%
-1.6% vs TC avg
§102
17.8%
-22.2% vs TC avg
§112
27.8%
-12.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1273 resolved cases

Office Action

§102
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . DETAILED ACTION This office action is in response to applicant’s reply filed on March 24, 2026. Restrictions/Elections. Applicant’s election without traverse of Group III (Claims 20-24) in the reply filed on March 24, 2026, is acknowledged. Status of Claims Claims 1-24 are currently pending and are the subject of this office action. Claims 1-19 are withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to a nonelected inventions, there being no allowable generic or linking claim. Election was made without traverse in the reply filed on March 24, 2026. Claims 20-24 are presently under examination. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 20-24 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Soman et. al. (Biochemistry (1986) 25:4113-4119). For claims 20-24, Soman teaches a solution of the following aminoguanidine imine (bezylidineamino guanidine): PNG media_image1.png 172 308 media_image1.png Greyscale (See page 4114, right column under “Physical Characterization of the Compounds”, and see Table I compound 1 on page 4115). Soman is silent regarding the solution being “a decontaminant product”. However, “a decontaminant product” seems to be claiming a property of the above solution anticipated by Soman. “A decontaminant product” will inevitably flow from the teachings of Soman (see above rejection) since both have the same structural components (a solution comprising an aminoguanidine imine). Apparently, Applicant has discovered a new property ("a decontaminant product”) of the composition anticipated by the prior art (a solution comprising an aminoguanidine imine). MPEP 2112 I states: “The discovery of a previously unappreciated property of a prior art composition, or of a scientific explanation for the prior art’s functioning, does not render the old composition patentably new to the discoverer.” Atlas Powder Co. v. Ireco Inc., 190 F.3d 1342, 1347, 51 USPQ2d 1943, 1947 (Fed. Cir. 1999). Thus, the claiming of a new use, new function or unknown property which is inherently present in the prior art does not necessarily make the claim patentable. In re Best, 562 F.2d 1252, 1254, 195 USPQ 430, 433 (CCPA 1977).” MPEP 2112.01 further states: "When the structure recited in the reference is substantially identical to that of the claims, claimed properties or functions (in the instant case: “a decontaminant product”) are presumed to be inherent”. “Where the claimed and prior art products are identical or substantially identical in structure or composition, or are produced by identical or substantially identical processes, a prima facie case of either anticipation or obviousness has been established. In re Best, 562 F.2d 1252, 1255, 195 USPQ 430, 433 (CCPA 1977). “When the PTO shows a sound basis for believing that the products of the applicant and the prior art are the same, the applicant has the burden of showing that they are not.” In re Spada, 911F.2d 705, 709, 15 USPQ2d 1655, 1658 (Fed. Cir. 1990).” The office does not have the facilities and resources to provide the factual evidence needed in order to establish that the formulation disclosed by Soman does not possess the same material, structural and functional characteristics of the composition claimed in the instant application. In the absence of evidence to the contrary, the burden is on the applicant to prove that the instant composition is different from those taught by the prior art and to establish patentable differences. See In re Best 562F.2d 1252, 195 USPQ 430 (CCPA 1977) and Ex parte Gray 10 USPQ 2d 1922 (PTO Bd. Pat. App. & Int. 1989). Conclusion No claims are allowed. Correspondence Any inquiry concerning this communication or earlier communications from the examiner should be directed to MARCOS L SZNAIDMAN whose telephone number is (571)270-3498. The examiner can normally be reached Flexing M-F 7 AM-7 PM. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Amy L. Clark can be reached on 571 272-1310. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /MARCOS L SZNAIDMAN/ Primary Examiner, Art Unit 1628 March 25, 2026.
Read full office action

Prosecution Timeline

Aug 01, 2023
Application Filed
Jul 08, 2026
Non-Final Rejection mailed — §102 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12734146
Cobalt-Porphyrin Complexes for the Inactivation of the Biological Activity of Opioids
4y 6m to grant Granted Sep 15, 2026
Patent 12714696
LOW DOSE FLURALANER COMPOSITIONS FOR PROTECTION AGAINST PARASITIC INVERTEBRATE PEST
4y 10m to grant Granted Aug 25, 2026
Patent 12697389
USE OF DIKETONE COMPOUND IN PHOTODYNAMIC THERAPY OR DIAGNOSIS
4y 8m to grant Granted Aug 04, 2026
Patent 12692234
ROCK INHIBITORS AND USES THEREOF
1y 1m to grant Granted Jul 28, 2026
Patent 12685725
PRIDOPIDINE FOR THE TREATMENT OF MITOCHONDRIAL-ASSOCIATED DISEASES AND DISORDERS AND ENDOPLASMIC RETICULUM (ER) STRESS
5y 4m to grant Granted Jul 21, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.
Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

1-2
Expected OA Rounds
37%
Grant Probability
54%
With Interview (+16.2%)
3y 6m (~4m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1273 resolved cases by this examiner. Grant probability derived from career allowance rate.

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month