Prosecution Insights
Last updated: April 19, 2026
Application No. 18/375,390

SYSTEMS AND METHODS FOR ALTERING THE SHAPE OF NASAL TISSUES

Final Rejection §103
Filed
Sep 29, 2023
Examiner
GANESAN, SUBA
Art Unit
3774
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Mayo Foundation for Medical Education and Research
OA Round
4 (Final)
74%
Grant Probability
Favorable
5-6
OA Rounds
3y 2m
To Grant
88%
With Interview

Examiner Intelligence

Grants 74% — above average
74%
Career Allow Rate
491 granted / 667 resolved
+3.6% vs TC avg
Moderate +14% lift
Without
With
+14.0%
Interview Lift
resolved cases with interview
Typical timeline
3y 2m
Avg Prosecution
30 currently pending
Career history
697
Total Applications
across all art units

Statute-Specific Performance

§101
0.6%
-39.4% vs TC avg
§103
45.5%
+5.5% vs TC avg
§102
26.6%
-13.4% vs TC avg
§112
19.3%
-20.7% vs TC avg
Black line = Tech Center average estimate • Based on career data from 667 resolved cases

Office Action

§103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Response to Arguments Applicant’s arguments filed 12/13/2025 have been fully considered but they are not persuasive. Applicant has amended claim 58 and 81-82 to recite the delivery device comprises a shaft with an angled tip at the distal end of the shaft. Applicant argues that Harrington’s delivery device is used to advance an anchor through a previously placed straight access needle, and thus would not be able to apss through the access needle if configured with an angled distal tip, and points to figures 5a-b and 6. This is not persuasive; the shaft of Harrington has a sharp angled tip (see fig. 6 and 7) and the anchor passes through the shaft (see fig. 7). Allowable Subject Matter Claims 61, and 68 are objected to as being dependent upon a rejected base claim, but would be allowable if rewritten in independent form including all of the limitations of the base claim and any intervening claims. The closest prior art is Harrington (Pub. No.: US 2012/0310280) in view of Dillard (Pub. No.: US 2020/0170823) as applied below, however, the combination does not fairly teach or suggest the plurality of migration prevention elements as closer to the proximal end than the distal end of the shaping element, or the at least one migration prevention element comprises a rachet element. Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. Claims 58, 60, 62-67, 69-78, 80-83 are rejected under 35 U.S.C. 103 as being unpatentable over Harrington (Pub. No.: US 2012/0310280) in view of Dillard (Pub. No.: US 2020/0170823). Harrington discloses a system for reshaping a nasal tissue of a subject (abstract), comprising: a delivery device (e.g., fig. 5a) sized and shaped for insertion into a nasal airway of the subject; the delivery device comprising a shaft (e.g., fig. 6, 7), and a guide movable within the shaft (e.g., fig. 7, 8), and an angled tip at a distal end of the shaft (e.g., fig. 6, 7); and a shaping element 5 comprising: an elongate body 6 having a relaxed state and a tensioned state (e.g., fig. 1, 2), a proximal end (e.g., end adjacent supporter 10), a distal end (e.g., end adjacent anchor 8), and an intermediate region therebetween (e.g., fig. 2); an anchor 8 positioned at the distal end of the elongate body configured to secure the shaping element 5 to the nasal tissue (e.g., fig. 1, 2); and at least one migration prevention element positioned along the intermediate region (not disclosed), wherein the elongate body 6 is configured to maintain a force on the nasal tissue to alter the shape of the nasal tissue in its tensioned state (e.g., para. 20). As provided in italicized text above, Harrington lacks at least one migration prevention element positioned along the intermediate region of the elongate body 6. Dillard teaches a system for reshaping nasal tissue of a subject (abstract) including an elongate body (CSM) including at least one migration prevention element (BD) positioned along the intermediate region (e.g., para. 33, fig. 3-4). Dillard teaches these migration prevention elements (BD) provide tension and hold against the soft tissue of the nose to change the shape of the nose (e.g., para. 60). It would have been obvious to one of ordinary skill in the art at the time the invention was filed to have provided the elongate body of Harrington with migration prevention elements as taught by Dillard for the purpose of providing a barbed connection to the soft tissue, preventing migration and allowing for tension along the elongate body to change the shape of the nose. This modification would have occurred using known methods and would have yielded predictable results. For claim 60, Dillard teaches the system of claim 58, further comprising a plurality of migration prevention elements (e.g., fig. 3, 4). For claim 62, Dillard teaches the system of claim 60, wherein the plurality of migration prevention elements comprises a plurality of protrusions (e.g., fig. 3, 4). For claim 63, Harrington and Dillard disclose the system of claim 58, wherein the nasal tissue is nasal septal tissue (Harrington fig. 1, tissue is fully capable of being septal tissue; Dillard para. 12). For claim 64, Harrington discloses the system of claim 58, wherein the delivery device has a lumen therethrough (e.g., fig. 7). For claim 65, Harrington and Dillard do not specify the system of claim 58, wherein the shaping element is between about 3 cm and about 30 cm in length, as neither reference specifies the desired length of the implant. However, use of a 3-30 cm length is considered an obvious expedient given the size of the human nose and the filamentous nature of the Harrington and Dillard implants. For claim 66, Harrington and Dillard discloses the system of claim 58, wherein the shaping element comprises PLPLA (Poly(L-lactide)), DLPLA (Poly(DL-lactide)), LDL-PLA (Poly(DL-lactide-co-L- lactide)), LPLA- HA (Poly(L-lactide) with hydroxylapatite), PGA (Poly(glycolide), PGA-TMC (Poly(glycolide-co-trimethylene carbonate) or polyglyconate), PDO (Poly(dioxanone)), LPLG (Poly(L-lactide-co-glycolide)), DLPLG (Poly(DL-lactide-co-glycolide), or combinations thereof (e.g., Harrington para. 20, Dillard para. 16). For claim 67, Dillard teaches the system of claim 66, wherein the shaping element comprises PDO (e.g., para. 16). For claim 69, Dillard teaches the system of claim 58, wherein the at least one migration prevention element is sized and shaped to pass through the nasal tissue in a first direction while being prevented from passing back through the nasal tissue in an opposite direction (barb, e.g., fig. 3,4). For claim 70, Harrington discloses the system of claim 58, further comprising a needle, wherein the needle is couplable to the shaping element to help direct the shaping element through the nasal tissue (e.g., fig. 6, 7). For claim 71, Harrington discloses the system of claim 58, wherein the delivery device comprises a curved portion (e.g., fig. 5a). For claim 72, Harrington discloses the system of claim 58, wherein the delivery device further comprises a handle 26 (e.g., fig. 5a). For claim 73, Harrington discloses the system of claim 58, wherein the delivery device further comprises an actuator 27 for delivering the shaping element (e.g., fig. 5a). For claim 74, Harrington discloses the system of claim 58, wherein a tip of the delivery device is atraumatic (e.g., fig. 5b, the sharp edge is part of the implant, with the delivery device end being atraumatic). For claim 75, Harrington discloses the system of claim 58, wherein the anchor comprises one or more of a T-fastener, and X-shaped fastener, a button, or a barb (e.g., fig. 4e, barb). For claim 76, Harrington discloses the system of claim 58, wherein the shaping element further comprises a force distributing region 10. For claim 77, Harrington discloses the system of claim 76, wherein the force distributing region has a width that is greater than the width of the shaping element adjacent to the force distributing region (e.g., fig. 2a). For claim 78, Harrington discloses the system of claim 58, wherein the shaft of the delivery device comprises one or more ports located on a sidewall thereof (e.g., fig. 6). For claim 80, Harrington discloses the system of claim 58, wherein the delivery device comprises a sharp tip (e.g., fig. 6-7). For claim 81, Harrington discloses a system for reshaping a nasal tissue of a subject, comprising: a delivery device sized and shaped for insertion into a nasal airway of the subject (e.g., fig. 5a), the delivery device comprising a shaft, (fig. 6) a guide 25 moveable within the shaft (e.g., fig. 5a, 6, 7), and an angled tip at a distal end of the shaft (e.g., fig. 6, 7); and a shaping element 5 coupled to the guide (e.g., fig. 5a, 7), and comprising: an elongate body 6 having a relaxed state and a tensioned state (e.g., fig. 2), a proximal end (end near element 10), a distal end (end near anchor 8), and an intermediate region therebetween; an anchor 8 positioned at the distal end of the elongate body (e.g., fig. 2); and at least one migration prevention element positioned along the intermediate region (not disclosed), wherein the elongate body is configured to maintain a force on the nasal tissue to alter the shape of the nasal tissue after deployment from the guide (e.g., para. 20). As provided in italicized text above, Harrington lacks at least one migration prevention element positioned along the intermediate region of the elongate body 6. Dillard teaches a system for reshaping nasal tissue of a subject (abstract) including an elongate body (CSM) including at least one migration prevention element (BD) positioned along the intermediate region (e.g., para. 33, fig. 3-4). Dillard teaches these migration prevention elements (BD) provide tension and hold against the soft tissue of the nose to change the shape of the nose (e.g., para. 60). It would have been obvious to one of ordinary skill in the art at the time the invention was filed to have provided the elongate body of Harrington with migration prevention elements as taught by Dillard for the purpose of providing a barbed connection to the soft tissue, preventing migration and allowing for tension along the elongate body to change the shape of the nose. This modification would have occurred using known methods and would have yielded predictable results. For claim 82, Harrington discloses the system of claim 81, wherein the elongate member comprises a sharp tip (e.g., para. 30). For claim 83, Harrington discloses the system of 81, wherein the guide 25 comprises a sharp tip (e.g., fig. 5b). Conclusion THIS ACTION IS MADE FINAL. Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to SUBA GANESAN whose telephone number is (571)272-3243. The examiner can normally be reached Monday-Friday, 8 AM - 5 PM Mountain Time. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Jerrah Edwards can be reached at (408) 918-7557. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /SUBA GANESAN/Primary Examiner, Art Unit 3774
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Prosecution Timeline

Sep 29, 2023
Application Filed
Sep 29, 2024
Non-Final Rejection — §103
Dec 30, 2024
Response Filed
Mar 03, 2025
Final Rejection — §103
Jun 04, 2025
Request for Continued Examination
Jun 09, 2025
Response after Non-Final Action
Sep 12, 2025
Non-Final Rejection — §103
Dec 13, 2025
Response Filed
Jan 05, 2026
Final Rejection — §103 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

5-6
Expected OA Rounds
74%
Grant Probability
88%
With Interview (+14.0%)
3y 2m
Median Time to Grant
High
PTA Risk
Based on 667 resolved cases by this examiner. Grant probability derived from career allow rate.

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