Prosecution Insights
Last updated: July 17, 2026
Application No. 18/427,489

AMINES FOR USE AS SIGMA RECEPTOR MODULATORS

Non-Final OA §112
Filed
Jan 30, 2024
Priority
Jul 01, 2020 — provisional 63/046,813 +2 more
Examiner
HABTE, KAHSAY
Art Unit
1624
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Ecstasy LLC
OA Round
1 (Non-Final)
85%
Grant Probability
Favorable
1-2
OA Rounds
0m
Est. Remaining
92%
With Interview

Examiner Intelligence

Grants 85% — above average
85%
Career Allowance Rate
1371 granted / 1612 resolved
+25.0% vs TC avg
Moderate +7% lift
Without
With
+7.4%
Interview Lift
resolved cases with interview
Fast prosecutor
1y 8m
Avg Prosecution
74 currently pending
Career history
1650
Total Applications
across all art units

Statute-Specific Performance

§101
2.5%
-37.5% vs TC avg
§103
3.7%
-36.3% vs TC avg
§102
9.0%
-31.0% vs TC avg
§112
63.9%
+23.9% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1612 resolved cases

Office Action

§112
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claims 1-3 are pending in this application. Election/Restrictions Applicant’s election of species of group d. (i.e. thiazoles derivatives that are attached to phenyl) in the reply filed on 05/25/2026 is acknowledged. Because applicant did not distinctly and specifically point out the supposed errors in the restriction requirement, the election has been treated as an election without traverse (MPEP § 818.01(a)). Applicants requested “thiadiazoles derivatives that are attached to the pyrrolidine core” be included in the election. The examiner agrees with applicants and included the “thiadiazole derivatives” in the examination. 3. Claims 1-3 are objected to because they are drawn to multiple inventions for reasons set forth in the restriction requirement. The claims are examined only to the extent that they read on the elected invention. Cancellation of the non-elected subject matter is recommended in response to this Office Action. In order to expedite prosecution, the examiner recommends that applicants delete non-elected species from claims 1-3. Claim Rejections - 35 USC § 112 4. The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. 5. Claim 1 is rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Claim 1 is rejected because it is unclear where the end of the claim is. Claim 1 has no period at the end of the claim. Information Disclosure Statement 6. Applicant’s Information Disclosure Statement, filed on 05/06/2026 and 12/04/2024 has been acknowledged. Please refer to Applicant’s copies of the 1449 submitted herewith. Objection 7. Claims 2-3 are objected to as being dependent upon a rejected base claim, but would be allowable if rewritten in independent form including all of the limitations of the base claim and any intervening claims. Note that according to item 3 above, the non-elected species should be deleted. Conclusion 8. Any inquiry concerning this communication or earlier communications from the examiner should be directed to Kahsay Habte Ph.D. whose telephone number is (571)272-0667. The examiner can normally be reached on 8:30 - 5:00 PM. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, JEFFREY MURRAY can be reached on 571-272-9023. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of an application may be obtained from the Patent Application Information Retrieval (PAIR) system. Status information for published applications may be obtained from either Private PAIR or Public PAIR. Status information for unpublished applications is available through Private PAIR only. For more information about the PAIR system, see https://ppair-my.uspto.gov/pair/PrivatePair. Should you have questions on access to the Private PAIR system, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative or access to the automated information system, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /Kahsay Habte/ Primary Examiner, Art Unit 1624 June 8, 2026
Read full office action

Prosecution Timeline

Jan 30, 2024
Application Filed
Jun 11, 2026
Non-Final Rejection mailed — §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
85%
Grant Probability
92%
With Interview (+7.4%)
1y 8m (~0m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1612 resolved cases by this examiner. Grant probability derived from career allowance rate.

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