Prosecution Insights
Last updated: April 19, 2026
Application No. 18/435,415

COMPOSITION FOR PREVENTING OR TREATING MUSCULAR DISEASE CONTAINING PONCIRI FRUCTUS EXTRACT

Non-Final OA §102
Filed
Feb 07, 2024
Examiner
MOREAU, NASHARA LOUISE
Art Unit
1655
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Korea Institute Of Science And Technology
OA Round
1 (Non-Final)
Grant Probability
Favorable
1-2
OA Rounds
2y 1m
To Grant

Examiner Intelligence

Grants only 0% of cases
0%
Career Allow Rate
0 granted / 0 resolved
-60.0% vs TC avg
Minimal +0% lift
Without
With
+0.0%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 1m
Avg Prosecution
24 currently pending
Career history
24
Total Applications
across all art units

Statute-Specific Performance

§101
12.5%
-27.5% vs TC avg
§103
43.8%
+3.8% vs TC avg
§102
15.6%
-24.4% vs TC avg
§112
27.1%
-12.9% vs TC avg
Black line = Tech Center average estimate • Based on career data from 0 resolved cases

Office Action

§102
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Election/Restrictions Applicant’s election without traverse of Group I, claim(s) 1-6 in the reply filed on February 13, 2026 is acknowledged. Claim(s) 7-13 are withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to a nonelected invention, there being no allowable generic or linking claim. Claim(s) 1-6 are examined on the merits. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 1-6 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Jeong Hee (KR 20140000627 A – English translation provided). Regarding claim(s) 1-6, the Jeong Hee reference teaches a composition that comprises the extract of Poncirus trifoliata ([e.g. Ponciri Fructus]) (abstract and claim 6). Jeong Hee teaches an immature fruit of Korean fruit (Poncirus trifoliate) (claim 5). Jeong Hee teaches the fruit ([e.g. Poncirus trifoliata]) is extracted with ethanol (page 4, ‘Experimental example 2-4’). Jeong Hee teaches treating myotonic dystrophy ([a type of muscular dystrophy]) (page 2, under ‘Background Art’ and claim 7). The reference does not specifically teach that administering the composition has the same effects on gene expression as claimed by applicant in claims 3 and 4 of the present invention. However, the ingestion of the extract would inherently increase the expression of the genes listed within claims 3 (Myf5, Myf6, Myod, and/or Myog) and 4 (Ppard or Pgc1a). Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to Nashara L Moreau whose telephone number is (571)272-5804. The examiner can normally be reached Monday - Thursday, 8 AM - 4 PM ET. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Anand U Desai can be reached at (571)272-0947. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. NASHARA L MOREAUExaminer, Art Unit 1655 /SUSAN HOFFMAN/Primary Examiner, Art Unit 1655
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Prosecution Timeline

Feb 07, 2024
Application Filed
Mar 20, 2026
Non-Final Rejection — §102 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12544416
MANUFACTURING METHOD FOR COMPOSITION PROMOTING BONE DENSITY ENHANCEMENT
2y 5m to grant Granted Feb 10, 2026
Study what changed to get past this examiner. Based on 1 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
Grant Probability
2y 1m
Median Time to Grant
Low
PTA Risk
Based on 0 resolved cases by this examiner. Grant probability derived from career allow rate.

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