DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA. Claims 1-20, filed 10/19/2023, are acknowledged. Claims 1-20 are pending and considered on the merits below. Priority Receipt is acknowledged of certified copies of papers required by 37 CFR 1.55. Information Disclosure Statement The Information Disclosure Statement filed on 10/19/2023 is in compliance with the provisions of 37 CFR 1.97 and has been considered. An initialed copy of the Form 1449 is enclosed herewith. Specification The disclosure is objected to because of the following informalities: [92] mentions “figure 22” but there is not figure 22 in the drawings . Appropriate correction is required. Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis ( i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale , or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 1-20 is/are rejected under 35 U.S.C. 102 (a)(1) as being anticipated by Guirguis ( US 2019/0049442 A1 ) . Regarding claim 1 , Guirguis describes a device for detecting an analyte in a liquid sample (abstract) , comprising: a sample chamber for accommodating a collector (figure 1 [0128] “ a collection chamber 40 ” ( sample chamber ) and [0129] “ fluid collector 20 ” ( collector ) and “ After the fluid sample has been collected, the fluid collector 20 is inserted into the collection chamber 40 ” ) ; and a detection chamber in fluid communication with the sample chamber (figure 1 “ test cartridge 50 ” ( detection chamber ) and figure 5 “ [0136] Referring still to FIGS. 1-5, a piping system fluidically couples the collection chamber 40 to the membrane test strips 31 and the immunoassay-based fingerprint acquisition pad 60. Tube 43 fluidically couples the lower portion 42 of the collection chamber 40 to adapter 44 and test cartridge fluid reservoir 45. ” ) ; wherein the detection chamber comprises a testing element therein, and the testing element is configured to detect the analyte in the liquid sample for the first time ([0132] “ Advantageously, different versions of the test cartridge 50 may be developed to test different combinations of analytes, thereby allowing the test administrator to select the appropriate analyte test suite at the test site. ”) ; and the sample chamber is detachably combined with the detection chamber, and the collector comprises a first absorption element that is used for absorbing the liquid sample and is capable to be compressed (figure 4 [0129] “ sponge 25 is attached to one end of the fluid collector 20 ” and “ the fluid sample is expelled by compressing the sponge 25 ” ) . Regarding claim 2 , Guirguis describes t he device according to claim 1, further comprising a secondary validation test chamber, wherein the secondary validation test chamber comprises a second absorption element that is capable to absorb the liquid sample and be compressed (figure 1 [0131] “ fingerprint acquisition pad 60 ( secondary validation test chamber ) ” and [0134] “immunoassay-based fingerprint acquisition pad 60 includes a compressible, porous reaction medium” ) . Regarding claim 3 , Guirguis describes t he device according to claim 2, wherein when the sample chamber comprises the collector, the first absorption element of the collector is capable to be compressed to release the liquid sample, wherein a part of the released liquid sample is capable to flow into the secondary validation test chamber and be absorbed by the second absorption element (figure 5 [0136] “ In this example, a "T" connection may be incorporated into tube 43 to fluidically couple tube 46 ” ) . Regarding claim 4 , Guirguis describes t he device according to claim 3, wherein the secondary validation test chamber is in fluid communication with the detection chamber, and the liquid sample absorbed by the second absorption element is used for secondary validation test (figure 5 [0136] “ a piping system fluidicly couples the collection chamber 40 to the membrane test strips 31 and the immunoassay-based fingerprint acquisition pad 60. Tube 43 fluidicly couples the lower portion 42 of the collection chamber 40 to adapter 44 and test cartridge fluid reservoir 45. Similarly, tube 46 fluidicly couples the lower portion 42 of collection chamber 40 to adapter 61, located just beneath immunoassay-based fingerprint acquisition pad 60. ”) . Regarding claim 5 , Guirguis describes t he device according to claim 4, wherein a volume of liquid sample absorbed by the second absorption element in the secondary validation test chamber to a saturated state is constant ( [0135] “ permeates the reaction medium, ” ) . Regarding claim 6 , Guirguis describes t he device according to claim 5, wherein a volume of the liquid sample released by compressing the first absorption element is greater than or equal to the volume of liquid sample absorbed by the second absorption element to a saturated state ([0144] “ Once a sufficient volume of the fluid sample has entered the lower channel 440, the fluid level rises until excess fluid flows through upper channel 445 and enters an absorbent pad, sample retention member 460 ” ) . Regarding claim 7 , Guirguis describes t he device according to claim 6, wherein the secondary validation test chamber is located in the sample chamber (figures 6 and 7 show the secondary validation test chamber (“60”) is located in the sample chamber (“40”) area. [0128] “ The housing 30 contains a collection chamber 40, … and an immunoassay-based fingerprint acquisition pad 60 ” ) . Regarding claim 8 , Guirguis describes t he device according to claim 7, wherein the secondary validation test chamber is in fluid communication with the detection chamber through a liquid channel (figure 5 [0128] “ The collection chamber 40 is in fluid communication, with the membrane test strips 51 and the immunoassay-based fingerprint acquisition pad 60. ” And [0132] “ the test cartridge 50, containing the membrane test strips 51 ” ) . Regarding claim 9 , Guirguis describes t he device according to claim 8, wherein the secondary validation test chamber is in fluid communication with the sample chamber through the detection chamber and the liquid channel (figure 5 [0128] “ The collection chamber 40 is in fluid communication, with the membrane test strips 51 and the immunoassay-based fingerprint acquisition pad 60. ” And [0132] “ the test cartridge 50, containing the membrane test strips 51 ” ) . Regarding claim 1 0 , Guirguis describes t he device according to claim 9, wherein the second absorption element is arranged on an absorber with a handle, and the absorber is capable to depart from the secondary validation test chamber ([0098] “ the absorbent material may be removably attached to the apparatus ” and [0115] “ According to an embodiment of the invention, the fluid collector includes a handle, for example made of wood, plastic, ceramic, or metal, and disposed, for example, at the end distal to the absorbent material. The handle may be removably attached, for example through an interference fit, adhesive, glue, or epoxy, that breaks or separates when the handle is twisted and/or pulled, or by a structure that allows the handle to be broken away, for example, a line of weakness. ” ) . Regarding claim 1 1 , Guirguis describes t he device according to claim 8, wherein the sample chamber comprises a first protrusion that comprises the liquid channel, and the first protrusion is detachably connected with a first recessed interface of the detection chamber, such that the sample chamber is capable to be in detachable communication with the detection chamber through the liquid channel (figure 4 [0131] “ the fluid collector 20 becomes secured within the collection chamber 40 after the fluid collector 20 is inserted into the collection chamber 40 to a predetermined depth. If desired, handle 23a may then be broken away from the upper surface of disk 21. ” ) . Regarding claim 1 2 , Guirguis describes t he device according to claim 11, wherein the sample chamber further comprises a cover, and the cover is configured to seal the liquid channel when the sample chamber and the detection chamber are separated ( [0112] “ A closure member may be used. The closure member is capable of sealing the open end of a sample receiving member when the fluid collector is inserted into the open end of a sample receiving member. For example, the closure member may be dimensioned to fit closely in the opening in the open end of the receiving member, and the closure member or the open end of the receiving member may include a compressible material, including without limitation natural rubber such as vulcanized rubber, synthetic rubber such as neoprene or nitrite rubber, plastic, ceramic, or any combination thereof, disposed at the interface between the closure member and the opening in the open end of the sample receiving member, capable of creating a seal, such as an airtight or a watertight seal, when the sample receiving member receives the fluid collector. ”) . Regarding claim 1 3 , Guirguis describes t he device according to claim 3, wherein when the sample chamber comprises the collector, the sample chamber is sealed by the collector, such that the secondary validation test chamber is hermetically sealed; in this way, if the secondary validation test chamber is capable to be compressed by moving the collector, gas in the secondary validation test chamber is allowed to be compressed to increase pressure therein ( [0095] “ In an embodiment of the invention, the receiving member may have an inner surface, for example a lower surface, that an absorbent material, such as an absorbent material present in a fluid collector, may be compressed against, thereby expelling the fluid sample from the absorbent material. For example, the absorbent material may be compressed directly between a compression member present on the fluid collector and the lower surface of the receiving member or the receiving member may provide structural support to facilitate compression of the absorbent material between a compression member and the housing that at least partially surrounds the absorbent material. ” And [0130] “ sealing rings 28 and 29 may be attached ” ) . Regarding claim 1 4 , Guirguis describes t he device according to claim 13, wherein the sample chamber further comprises a movable chamber, the movable chamber is configured to receive the collector and allow the first absorption element to be compressed to release the liquid sample, and the movable chamber has a first position and a second position in the sample chamber ([0129] “ A sponge 25 is attached to one end of the fluid collector 20 to absorb, and temporarily store, the fluid sample. The sponge 25 may be saturated with a saliva-producing substance. After the fluid sample has been collected, the fluid collector 20 is inserted into the collection chamber 40 through the opening 32, and the fluid sample is expelled by compressing the sponge 25 against the bottom surface of the lower portion 42 of the collection chamber 40, ” ) . Regarding claim 1 5 , Guirguis describes The device according to claim 13, wherein when the absorption element is compressed to release the liquid, the released liquid flows to the secondary validation test chamber, the second absorption element is allowed to absorb the liquid, and the excess liquid flows to the detection chamber through the liquid channel to contact the testing element for testing and assaying, and the movable chamber is located at the first position ([0129] “ A sponge 25 is attached to one end of the fluid collector 20 to absorb, and temporarily store, the fluid sample. The sponge 25 may be saturated with a saliva-producing substance. After the fluid sample has been collected, the fluid collector 20 is inserted into the collection chamber 40 through the opening 32, and the fluid sample is expelled by compressing the sponge 25 against the bottom surface of the lower portion 42 of the collection chamber 40, ” ) . Regarding claim 1 6 , Guirguis describes t he device according to claim 15, wherein after the collector and the detection chamber are separated, and when secondary validation test needs to be performed, the movable chamber and the collector are allowed to move together to the second position, and the second absorption element is compressed by the movable chamber, whereby releasing the liquid through the liquid channel; and the released liquid is used for secondary validation test ([0138] “ compressing the sponge 25 against the bottom surface of the lower portion 42 of the collection chamber 40, thereby releasing the entrapped fluid into the tubes 43 and 46. Projections 26 extend from the upper surface of disk 21 and cooperate with an annular projection 53, located on the inner surface of the collection chamber 40, to secure the fluid collector 20 within the collection chamber 40. ” ) . Regarding claim 1 7 , Guirguis describes t he device according to claim 16, wherein the detection chamber comprises a carrier for carrying the testing element, the testing element is located on the carrier, and the detection chamber is in communication with external atmosphere ([0065] “ As the fluid sample migrates along the membrane test strip by capillary action, it carries the labeled anti-analyte antibody along until it reaches the test region. ”) . Regarding claim 1 8 , Guirguis describes t he device according to claim 1, further comprising a base, wherein the detection chamber and the sample chamber are located on the base and combined with the base in a detachable manner ( [0128] “ FIGS. 1-5 depict a fluid collection and analyte testing device in accordance with an embodiment of the present invention. Analyte screening device 10 includes a fluid collector 20, to collect a fluid sample from a test subject, and a housing 30 to test and retain the fluid sample. The housing 30 contains a collection chamber 40, to receive the fluid collector 20 through an opening 32, at least one membrane test strip 51, to indicate the presence or absence of at least one analyte, and an immunoassay-based fingerprint acquisition pad 60 to positively identify an individual associated with the test. The collection chamber 40 is in fluid communication, with the membrane test strips 51 and the immunoassay-based fingerprint acquisition pad 60. ” ) . Regarding claim 1 9 , Guirguis describes t he device according to claim 1, wherein the analyte is a drug micromolecule ( [0076] “ analytes that may be tested for include drugs of abuse or their metabolites, analytes indicating the presence of an infectious agent or product of an infectious agent, allergen, pollutant, toxin, contaminant, analyte with diagnostic or medical value, antibody against any of the foregoing, and any combination thereof. ” And [0216] “ A single drug, or class of drugs, is indicated by each membrane test strip 1206, including without limitation, for example, cocaine (COC), amphetamine (AMP), methamphetamine ( mAMP ), marijuana (THC), methadone (MTD), phencyclidine (PCP), morphine, barbiturates, benzodiazepines, or alcohol. In one embodiment, the test strips 1106 may be lateral flow test strips. ” ) . Regarding claim 20 , Guirguis describes t he device according to claim 1, wherein the liquid sample is saliva, urine or blood ([0063] “ fluid sample may be saliva, urine, blood, ”) . Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to FILLIN "Examiner name" \* MERGEFORMAT EMILY R BERKELEY whose telephone number is FILLIN "Phone number" \* MERGEFORMAT (571)272-9831 . The examiner can normally be reached FILLIN "Work Schedule?" \* MERGEFORMAT M-Th 9-6 . Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, FILLIN "SPE Name?" \* MERGEFORMAT Lyle Alexander can be reached at FILLIN "SPE Phone?" \* MERGEFORMAT (571) 272-1254 . The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /LYLE ALEXANDER/ Supervisory Patent Examiner, Art Unit 1797 FILLIN "Examiner Stamp" \* MERGEFORMAT /EMILY R. BERKELEY/ Examiner Art Unit 1796