Office Action Predictor
Last updated: April 15, 2026
Application No. 18/490,881

Multi-Parametric Machine Olfaction

Non-Final OA §102§103
Filed
Oct 20, 2023
Examiner
BOLDUC, DAVID J
Art Unit
2852
Tech Center
2800 — Semiconductors & Electrical Systems
Assignee
Brown University
OA Round
1 (Non-Final)
84%
Grant Probability
Favorable
1-2
OA Rounds
2y 2m
To Grant
91%
With Interview

Examiner Intelligence

Grants 84% — above average
84%
Career Allow Rate
599 granted / 713 resolved
+16.0% vs TC avg
Moderate +7% lift
Without
With
+7.3%
Interview Lift
resolved cases with interview
Typical timeline
2y 2m
Avg Prosecution
16 currently pending
Career history
729
Total Applications
across all art units

Statute-Specific Performance

§101
2.2%
-37.8% vs TC avg
§103
46.2%
+6.2% vs TC avg
§102
29.2%
-10.8% vs TC avg
§112
20.3%
-19.7% vs TC avg
Black line = Tech Center average estimate • Based on career data from 713 resolved cases

Office Action

§102 §103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claim Rejections - 35 USC § 102/103 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. The factual inquiries for establishing a background for determining obviousness under 35 U.S.C. 103 are summarized as follows: 1. Determining the scope and contents of the prior art. 2. Ascertaining the differences between the prior art and the claims at issue. 3. Resolving the level of ordinary skill in the pertinent art. 4. Considering objective evidence present in the application indicating obviousness or nonobviousness. Claim(s) 4 is/are rejected under 35 U.S.C. 102(a)(1) as anticipated by or, in the alternative, under 35 U.S.C. 103 as obvious over US 20040101851 to White. Regarding Claim 4, White discloses a method of machine olfaction (Figs. 1-4, sensing device for analytes (odors); ¶¶ [0101]-[0116]) comprising the steps of: passing an analyte vapor through a temporal airflow modulator configured to selectively pass an airflow and the analyte vapor (Figs. 1-4, analyte delivery and control system (i.e. manipulation of spatial and temporal distributions; control over temperature, humidity, and duty cycle); ¶¶ [0101]-[0116]); and passing the analyte vapor through a multi-parametric sensing unit (Figs. 1-4, detection by sensor array with multiple/differing parameters and control and measurement of temperature; ¶¶ [0101]-[0116], [0259]-[0286]). Claim(s) 1-8 is/are rejected under 35 U.S.C. 103 as being unpatentable over White in view of US 20150302728 to Gettings. Regarding Claim 1, White discloses a system for machine olfaction (Figs. 1-4, sensing device for analytes (odors); ¶¶ [0101]-[0116]) comprising: an array of temperature-controlled sensor pairs (Figs. 1-4, sensing array with pairs of opposed light emitting diode light sources and photodiode photodetectors and means for controlling temperature; ¶¶ [0101]-[0116]); and a computer configured to provide power to the array of sensor pairs (Figs. 1-4, computer control of LEDs powered by a single constant voltage circuit or each LED powered independently by its own constant current circuitry; ¶¶ [0101]-[0116], [0137]-[0143]). However, White is silent regarding the computer configured to wirelessly transmit data from the array of sensor pairs to a host computer. Gettings discloses the computer configured to wirelessly transmit data from the array of sensor pairs to a host computer (Figs. 1-2, communication among environmental monitoring devices 110, optional electronic devices 114) and data-sharing electronic device 118 using wireless signals, and communication with optional computer 120 and optional network 122 (such as the Internet, a wireless local area network, an Ethernet network, an intra-net, an optical network, etc.) and aggregating or archive device 116 (which may or may not involve wireless signals); ¶¶ [0053]-[0056]). It would have been obvious to one of ordinary skill in the art before the effective filing of the application to modify the invention of White by providing the computer configured to wirelessly transmit data from the array of sensor pairs to a host computer as in Gettings in order to provide for a well-known alternative to wired communication. See, e.g., "substitution of art-recognized equivalents" as discussed in MPEP 2144.06II "An express suggestion to substitute one equivalent component or process for another is not necessary to render such substitution obvious. In re Fout, 675 F.2d 297, 213 USPQ 532 (CCPA 1982)." Regarding Claim 2, White discloses each pair of sensors comprises one Volatile Organic Compound (VOC) sensor (Figs. 1-4, detection of volatile compounds by sensor array with multiple/differing parameters with control and measurement of temperature; ¶¶ [0101]-[0116], Claims 1-6) and Gettings discloses each pair of sensors comprises one Volatile Organic Compound (VOC) sensor and one digital barometer (Figs. 1-2, sensor subsystem 218 may include one or more sensor devices 228 (or a sensor array), which may include a thermal sensor (such as a thermometer), a humidity sensor, a barometer, and a volatile-organic-compound sensor; ¶ [0077]). Regarding Claim 3, White discloses said computer is a plurality of computers (Figs. 1-4, computer control of LEDs powered by a single constant voltage circuit or each LED powered independently by its own constant current circuitry; ¶¶ [0101]-[0116], [0137]-[0143]). AND Gettings discloses said computer is a plurality of computers (Figs. 1-2, communication among environmental monitoring devices 110, optional electronic devices 114) and data-sharing electronic device 118 using wireless signals, and communication with optional computer 120 and optional network 122 (such as the Internet, a wireless local area network, an Ethernet network, an intra-net, an optical network, etc.) and aggregating or archive device 116 (which may or may not involve wireless signals); ¶¶ [0053]-[0056]). Regarding Claim 4, White discloses a method of machine olfaction (Figs. 1-4, sensing device for analytes (odors); ¶¶ [0101]-[0116]) comprising the steps of: passing an analyte vapor through a temporal airflow modulator configured to selectively pass an airflow and the analyte vapor (Figs. 1-4, analyte delivery and control system (i.e. manipulation of spatial and temporal distributions; control over temperature, humidity, and duty cycle); ¶¶ [0101]-[0116]); and passing the analyte vapor through a multi-parametric sensing unit (Figs. 1-4, detection by sensor array with multiple/differing parameters and control and measurement of temperature; ¶¶ [0101]-[0116], [0259]-[0286]). Assuming arguendo that White does not sufficiently disclose a multi-parametric sensing unit, Gettings discloses a multi-parametric sensing unit (Figs. 1-2, sensor subsystem 218 may include one or more sensor devices 228 (or a sensor array), which may include a thermal sensor (such as a thermometer), a humidity sensor, a barometer, and a volatile-organic-compound sensor; ¶ [0077]). It would have been obvious to one of ordinary skill in the art before the effective filing of the application to modify the invention of White by providing a multi-parametric sensing unit as in Gettings in order to provide greater accuracy. Regarding Claim 5, Gettings discloses said multi-parametric sensing unit is configured to react to a chemical parameter, a pressure parameter and a temperature parameter (Figs. 1-2, sensor subsystem 218 may include one or more sensor devices 228 (or a sensor array), which may include a thermal sensor (such as a thermometer), a humidity sensor, a barometer, and a volatile-organic-compound sensor; ¶ [0077]). Regarding Claim 6, White discloses said multi-parametric sensing unit comprises: an array of temperature-controlled sensor pairs (Figs. 1-4, sensing array with pairs of opposed light emitting diode light sources and photodiode photodetectors and means for controlling temperature; ¶¶ [0101]-[0116]); and a computer configured to provide power to the array of sensor pairs (Figs. 1-4, computer control of LEDs powered by a single constant voltage circuit or each LED powered independently by its own constant current circuitry; ¶¶ [0101]-[0116], [0137]-[0143]) and Gettings discloses the computer configured to wirelessly transmit data from the array of sensor pairs to a host computer (Figs. 1-2, communication among environmental monitoring devices 110, optional electronic devices 114) and data-sharing electronic device 118 using wireless signals, and communication with optional computer 120 and optional network 122 (such as the Internet, a wireless local area network, an Ethernet network, an intra-net, an optical network, etc.) and aggregating or archive device 116 (which may or may not involve wireless signals); ¶¶ [0053]-[0056]). Regarding Claim 7, White discloses each pair of sensors comprises one Volatile Organic Compound (VOC) sensor (Figs. 1-4, detection of volatile compounds by sensor array with multiple/differing parameters with control and measurement of temperature; ¶¶ [0101]-[0116], Claims 1-6) and Gettings discloses each pair of sensors comprises one Volatile Organic Compound (VOC) sensor and one digital barometer (Figs. 1-2, sensor subsystem 218 may include one or more sensor devices 228 (or a sensor array), which may include a thermal sensor (such as a thermometer), a humidity sensor, a barometer, and a volatile-organic-compound sensor; ¶ [0077]). Regarding Claim 8, White discloses said computer is a plurality of computers (Figs. 1-4, computer control of LEDs powered by a single constant voltage circuit or each LED powered independently by its own constant current circuitry; ¶¶ [0101]-[0116], [0137]-[0143]). AND Gettings discloses said computer is a plurality of computers (Figs. 1-2, communication among environmental monitoring devices 110, optional electronic devices 114) and data-sharing electronic device 118 using wireless signals, and communication with optional computer 120 and optional network 122 (such as the Internet, a wireless local area network, an Ethernet network, an intra-net, an optical network, etc.) and aggregating or archive device 116 (which may or may not involve wireless signals); ¶¶ [0053]-[0056]). Claim(s) 9-10 is/are rejected under 35 U.S.C. 103 as being unpatentable over White in view of US 20180364207 to Roberts. Regarding Claim 9, White discloses a system (Figs. 1-4, sensing device for analytes (odors); ¶¶ [0101]-[0116]) comprising: an array of temperature-controlled sensor pairs (Figs. 1-4, sensing array with pairs of opposed light emitting diode light sources and photodiode photodetectors and means for controlling temperature; ¶¶ [0101]-[0116]); and a computer configured to provide power to the array of sensor pairs, and to transmit data from the array of sensor pairs to a host computer configured to analyze the data (Figs. 1-4, computer control of LEDs powered by a single constant voltage circuit or each LED powered independently by its own constant current circuitry; ¶¶ [0101]-[0116], [0137]-[0143]).. However, White is silent regarding a single-board computer configured to provide power to the array of sensor pairs, and to wirelessly transmit data from the array of sensor pairs to a host computer configured to analyze the data. Roberts discloses a single-board computer configured to provide power to the array of sensor pairs, and to wirelessly transmit data from the array of sensor pairs to a host computer configured to analyze the data (Figs. 1-4, output of the detector 30 component communicated wirelessly to the external environment with Raspberry PI board); ¶¶ [0076],[0112]). It would have been obvious to one of ordinary skill in the art before the effective filing of the application to modify the invention of White by providing a single-board computer configured to provide power to the array of sensor pairs, and to wirelessly transmit data from the array of sensor pairs to a host computer configured to analyze the data as in Roberts in order to provide for a well-known alternative to wired communication. See, e.g., "substitution of art-recognized equivalents" as discussed in MPEP 2144.06II "An express suggestion to substitute one equivalent component or process for another is not necessary to render such substitution obvious. In re Fout, 675 F.2d 297, 213 USPQ 532 (CCPA 1982)." Regarding Claim 10, White discloses said array of sensor pairs comprises at least eight sensor pairs (Figs. 1-4, sensing array with pairs of opposed light emitting diode light sources and photodiode photodetectors with 16 channels; ¶¶ [0101]-[0116]). Claim(s) 11 is/are rejected under 35 U.S.C. 103 as being unpatentable over White in view of Roberts and Gettings. Regarding Claim 11, White in view of Roberts discloses the system of claim 9 and White further discloses each pair of sensors comprises one Volatile Organic Compound (VOC) sensor (Figs. 1-4, detection of volatile compounds by sensor array with multiple/differing parameters with control and measurement of temperature; ¶¶ [0101]-[0116], Claims 1-6). However, White in view of Roberts is silent regarding one digital barometer. Gettings discloses each pair of sensors comprises one Volatile Organic Compound (VOC) sensor and one digital barometer (Figs. 1-2, sensor subsystem 218 may include one or more sensor devices 228 (or a sensor array), which may include a thermal sensor (such as a thermometer), a humidity sensor, a barometer, and a volatile-organic-compound sensor; ¶ [0077]). It would have been obvious to one of ordinary skill in the art before the effective filing of the application to modify the invention of White in view of Roberts by providing one digital barometer as in Gettings in order to provide for greater accuracy. Claim(s) 12 is/are rejected under 35 U.S.C. 103 as being unpatentable over White in view of Roberts and Gettings, and further in view of US 20180120278 to Hoorfar. Regarding Claim 12, White in view of Roberts and Gettings discloses the system of claim 11, but are silent regarding each VOC sensor comprises a micro-hotplate metal-oxide (MOX) sensor with integrated resistive heaters configured to respond to a presence of volatile molecules. Hoorfar discloses each VOC sensor comprises a micro-hotplate metal-oxide (MOX) sensor with integrated resistive heaters configured to respond to a presence of volatile molecules (Figs. 1-3, Metal Oxide VOC gas sensor with integrated heaters; ¶¶ [0013]-[0015], [0043], [0099]). It would have been obvious to one of ordinary skill in the art before the effective filing of the application to modify the invention of White in view of Roberts and Gettings by providing each VOC sensor comprises a micro-hotplate metal-oxide (MOX) sensor with integrated resistive heaters configured to respond to a presence of volatile molecules as in Hoorfar in order to provide for a well-known alternative type of gas sensor. See, e.g., "substitution of art-recognized equivalents" as discussed in MPEP 2144.06II "An express suggestion to substitute one equivalent component or process for another is not necessary to render such substitution obvious. In re Fout, 675 F.2d 297, 213 USPQ 532 (CCPA 1982)." Claim(s) 13 is/are rejected under 35 U.S.C. 103 as being unpatentable over White in view of Roberts and Gettings, and further in view of US 20170203958 to Classen. Regarding Claim 13, White in view of Roberts and Gettings discloses the system of claim 11, but are silent regarding each digital barometer comprises a small MEMS sensor with piezoresistive elements on a thin suspended membrane. Classen discloses each digital barometer comprises a small MEMS sensor with piezoresistive elements on a thin suspended membrane (Fig. 5, pressure sensor structure 12 including a pressure sensor diaphragm 18 and a piezoelectric resistor 19; ¶¶ [0007], [0049]). It would have been obvious to one of ordinary skill in the art before the effective filing of the application to modify the invention of White in view of Roberts and Gettings by providing each digital barometer comprises a small MEMS sensor with piezoresistive elements on a thin suspended membrane as in Classen in order to provide for a well-known alternative type of gas sensor. See, e.g., "substitution of art-recognized equivalents" as discussed in MPEP 2144.06II "An express suggestion to substitute one equivalent component or process for another is not necessary to render such substitution obvious. In re Fout, 675 F.2d 297, 213 USPQ 532 (CCPA 1982)." Claim(s) 14 is/are rejected under 35 U.S.C. 103 as being unpatentable over White in view of Roberts and further in view of US 5832411 to Schatzmann. Regarding Claim 14, White in view of Roberts discloses the system of claim 9, but are silent regarding a DAC for controlling temperature of said temperature-controlled pairs. Schatzmann discloses a DAC for controlling temperature of said temperature-controlled pairs (Figs. 1-2, heater 86 with driver circuit 100 for DAC control; Col. 8, lines 14-56). It would have been obvious to one of ordinary skill in the art before the effective filing of the application to modify the invention of White in view of Roberts by providing a DAC for controlling temperature of said temperature-controlled pairs as in Schatzmann in order to provide for a well-known alternative type of heater control. See, e.g., "substitution of art-recognized equivalents" as discussed in MPEP 2144.06II "An express suggestion to substitute one equivalent component or process for another is not necessary to render such substitution obvious. In re Fout, 675 F.2d 297, 213 USPQ 532 (CCPA 1982)." Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to DAVID J BOLDUC whose telephone number is (571)270-1602. The examiner can normally be reached M-F, 10am-6pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Walter Lindsay, Jr. can be reached at (571) 272-1672. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /DAVID J BOLDUC/Primary Examiner, Art Unit 2852
Read full office action

Prosecution Timeline

Oct 20, 2023
Application Filed
Jan 10, 2026
Non-Final Rejection — §102, §103
Apr 07, 2026
Response Filed

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12596006
SYNCHRONIZED MASS GYROSCOPE WITH FULL SYMMETRY AND TURNABILITY
2y 5m to grant Granted Apr 07, 2026
Patent 12591189
DEVELOPER SUPPLY CONTAINER AND DEVELOPER SUPPLYING SYSTEM
2y 5m to grant Granted Mar 31, 2026
Patent 12571633
SYSTEM AND METHOD FOR DETERMINING A FREQUENCY AND/OR FREQUENCY CHANGE OF A DRIVE OSCILLATION OF AN INERTIAL SENSOR
2y 5m to grant Granted Mar 10, 2026
Patent 12546754
ANALYZER COLUMN CARTRIDGE
2y 5m to grant Granted Feb 10, 2026
Patent 12540613
TEST DEVICE
2y 5m to grant Granted Feb 03, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

AI Strategy Recommendation

Get an AI-powered prosecution strategy using examiner precedents, rejection analysis, and claim mapping.
Powered by AI — typically takes 5-10 seconds

Prosecution Projections

1-2
Expected OA Rounds
84%
Grant Probability
91%
With Interview (+7.3%)
2y 2m
Median Time to Grant
Low
PTA Risk
Based on 713 resolved cases by this examiner. Grant probability derived from career allow rate.

Sign in for Full Analysis

Enter your email to receive a magic link. No password needed.

Free tier: 3 strategy analyses per month