Last updated: July 31, 2026

Application No. 18/540,512

COMPOSITIONS AND METHODS FOR PERFORMING HYBRIDIZATIONS WITH NO DENATURATION

Non-Final OA

Filed

Dec 14, 2023

Priority

Dec 02, 2009 — provisional 61/265,966 +3 more

Examiner

LEWIS, PATRICK T

Art Unit

1691

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Agilent Technologies Inc.

OA Round

1 (Non-Final)

Interview Optional

— +14.3% interview lift. Interview lift (+14.3%) is below the 15.0% threshold. A written response is recommended.

Based on 1161 resolved cases, 2023–2026

Examiner Intelligence

LEWIS, PATRICK T View full profile →

Grants 74% — above average

Career Allowance Rate

861 granted / 1161 resolved

+14.2% vs TC avg

Moderate +14% lift

Without

With

+14.3%

Interview Lift

resolved cases with interview

Typical timeline

2y 3m

Avg Prosecution

17 currently pending

Career history

1181

Total Applications

across all art units

Statute-Specific Performance

§101

2.3%

-37.7% vs TC avg

§103

55.1%

+15.1% vs TC avg

§102

20.0%

-20.0% vs TC avg

§112

12.8%

-27.2% vs TC avg

Black line = Tech Center average estimate • Based on career data from 1161 resolved cases

Prosecution Timeline

Dec 14, 2023

Application Filed

Apr 30, 2026

Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

17/681,731

Patent 12686698

FAST DEPROTECTING N-EXOCYCLIC AMINO CYCLIC HYDROCARBON PROCETING GROUPS FOR NUCLEOSIDE PHOSPHORAMIDITES

4y 4m to grant Granted Jul 21, 2026

18/548,110

Patent 12685313

AGRICULTURAL COMPOSITION COMPRISING KASUGAMYCIN

2y 10m to grant Granted Jul 21, 2026

18/258,977

Patent 12661369

MUSCULAR ATROPHY INHIBITOR AND METHOD FOR INHIBITING MUSCULAR ATROPHY

3y 0m to grant Granted Jun 23, 2026

18/040,182

Patent 12642812

NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND USE THEREOF IN THE TREATMENT AND PREVENTION OF AN ANTINEOPLASTIC-INDUCED TOXICITY

3y 4m to grant Granted Jun 02, 2026

18/125,335

Patent 12636305

COMPOSITION AND METHOD OF APPLYING SAME TO INCREASE SURVIVAL OF FISH FOLLOWING CATCH-AND-RELEASE SITUATIONS

3y 2m to grant Granted May 26, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

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Prosecution Projections

1-2

Expected OA Rounds

74%

Grant Probability

88%

With Interview (+14.3%)

2y 3m (~0m remaining)

Median Time to Grant

Low

PTA Risk

Based on 1161 resolved cases by this examiner. Grant probability derived from career allowance rate.