Prosecution Insights
Last updated: July 17, 2026
Application No. 18/547,610

ORGANOANTIMONY(V) CYANOXIMATE COMPOUNDS AND METHODS OF PRODUCTION AND USE THEREOF

Non-Final OA §102§103
Filed
Aug 23, 2023
Priority
Feb 23, 2021 — provisional 63/152,490 +2 more
Examiner
ROBINSON, MIKHAIL O'DONNEL
Art Unit
1627
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Missouri State University
OA Round
2 (Non-Final)
58%
Grant Probability
Moderate
2-3
OA Rounds
5m
Est. Remaining
99%
With Interview

Examiner Intelligence

Grants 58% of resolved cases
58%
Career Allowance Rate
69 granted / 120 resolved
-2.5% vs TC avg
Strong +43% interview lift
Without
With
+42.7%
Interview Lift
resolved cases with interview
Typical timeline
3y 4m
Avg Prosecution
43 currently pending
Career history
159
Total Applications
across all art units

Statute-Specific Performance

§101
0.9%
-39.1% vs TC avg
§103
64.5%
+24.5% vs TC avg
§102
11.7%
-28.3% vs TC avg
§112
6.8%
-33.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 120 resolved cases

Office Action

§102 §103
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Response to Arguments Applicant’s arguments, see Page 2, filed 04/20/2026, with respect to the 112b rejection over claims 1-20 by the amendment to claim 1 have been fully considered and are persuasive. The 112b rejection of claims 1-20 has been withdrawn. Applicants remarks to the 102 rejection of claims 1-2, 4-5, 9 and 16-17 over Domasevitch et al; Organoantimony(V) Cyanoximates: Synthesis, Spectra and Crystal Structures, T. Shevchenko University, Inorg. Chemistry, March 2000, Pages 1227-1237 is rendered moot. Applicant has added the limitations of claim 11 of the antimicrobial activity of the at least one organoantimony(V) cyanoximate into claims 1 and 16. Domasevitch (Page 1228) teaches the compound having antimicrobial activity by the properties of the Cyanoximes, thus the teachings of Domasevitch reads to the amendment of claims 1 and 16. Applicant has canceled claim 11. Claims 1-10 and 12-20 is pending. Claims 1-10 and 12-20 is now evaluated on its merits. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claims 1-2, 4-6, 9 and 16-17 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Domasevitch et al; Organoantimony(V) Cyanoximates: Synthesis, Spectra and Crystal Structures, T. Shevchenko University, Inorg. Chemistry, March 2000, Pages 1227-1237. Regarding claims 1-2, 4-6, 9 and 16-17, Domasevitch teaches an organoantimony(V) cyanoximates synthesized and studied (relevant to claim 16) (abstract) comprising compound R4SbL, wherein R is a phenyl and L is cyanoximate group (relevant to claim 1) and R3Sb(Hal)L wherein R is a phenyl and L is cyanoximate group and Hal is F, Cl or Br (relevant to claim 6) (Page 1228, 2nd column). The R4SbL has taught by Domasevitch demonstrates antimicrobial properties (Page 1228, first column). Domasevitch additionally teaches compound PNG media_image1.png 90 171 media_image1.png Greyscale (relevant to claims 2, 4-5, 9 and 17) (Page 1236, Figure 7). Claims 1-6, 9, 12-13 and 15-20 are rejected under 35 U.S.C. 102 (a)(1) as being anticipated by Pinks, Synthesis, Characterization, and Biological Studies of Novel Synthesis, Characterization, and Biological Studies of Novel Organoantimony(V) Cyanoximates, 2020, Pages 1-163. Regarding claims 1-6, 9, 12-13 and 15-20, Pinks teaches a method for inhibiting and/or preventing microbial and fungal growth by administration of organoantimony(V) cyanoximates by disk assays (relevant to claims 1, 12-13, 15 and 18-20). The organoantimony(V) cyanoximates that showed the greatest antimicrobial inhibition were Sb(Ph)4(ACO), Sb(Ph)4(ECO), Sb(Ph)4(TCO) and Sb(Ph)4(TDCO) (abstract). Of the organoantimony(V) cyanoximates Pinks teaches the synthesis by combining organoantimony(V) compound with cyanoximate compounds of PNG media_image2.png 131 616 media_image2.png Greyscale PNG media_image3.png 274 611 media_image3.png Greyscale to get compounds of (relevant to claims 2-6, 9 and 16-17). Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. Claim 14 is rejected under 35 U.S.C. 103 as being unpatentable over Pinks, Synthesis, Characterization, and Biological Studies of Novel Synthesis, Characterization, and Biological Studies of Novel Organoantimony(V) Cyanoximates, 2020, Pages 1-163.The teachings of Pinks from the above 102 rejection of claims 1-6, 9, 12-13 and 15-20 is incorporated herein by reference. Pinks fails to teach the composition comprising an adhesive. Pinks, however teaches antimicrobial and antifungal testing is required to understand how practical Sb(V) cyanoximates are for treatment, which includes heterocyclic cyanoximes (Pg. 97). Additionally, the compounds have been used traditionally on many applications such as cosmetic (Pg. 7). Therefore, it would have been obvious to someone of ordinary skill in the art to have tested the above compounds taught by Pink with an adhesive. One would have been motivated to do so from the teachings of Pink of the compound being used as cosmetic applications which is known in the art to use an adhesive, additionally testing different type of applications is of routine experimentation for testing antibacterial and antifungal therapeutics to be applied. Allowable Subject Matter Claims 7-8 and 10 are objected to as being dependent upon a rejected base claim, but would be allowable if rewritten in independent form including all of the limitations of the base claim and any intervening claims. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to MIKHAIL O'DONNEL ROBINSON whose telephone number is (571)270-0777. The examiner can normally be reached Monday-Friday 7:30am-5:30pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Kortney Klinkel can be reached at 571-270-5239. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. MIKHAIL O'DONNEL. ROBINSON Examiner Art Unit 1627 /MIKHAIL O'DONNEL ROBINSON/Examiner, Art Unit 1627 /SARAH PIHONAK/Primary Examiner, Art Unit 1627
Read full office action

Prosecution Timeline

Aug 23, 2023
Application Filed
Dec 18, 2025
Non-Final Rejection mailed — §102, §103
Apr 20, 2026
Response Filed
Jul 02, 2026
Non-Final Rejection mailed — §102, §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

2-3
Expected OA Rounds
58%
Grant Probability
99%
With Interview (+42.7%)
3y 4m (~5m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 120 resolved cases by this examiner. Grant probability derived from career allowance rate.

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