Prosecution Insights
Last updated: August 07, 2026
Application No. 18/551,180

NITROGEN-CONTAINING HETEROCYCLIC POLYCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Non-Final OA §102
Filed
Sep 18, 2023
Priority
Mar 16, 2021 — CN 202110280887.4 +4 more
Examiner
SEAMAN, D MARGARET M
Art Unit
1625
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Jiangsu Hansoh Pharmaceutical Group Co. Ltd.
OA Round
1 (Non-Final)
77%
Grant Probability
Favorable
1-2
OA Rounds
0m
Est. Remaining
85%
With Interview

Examiner Intelligence

Grants 77% — above average
77%
Career Allowance Rate
1070 granted / 1397 resolved
+16.6% vs TC avg
Moderate +8% lift
Without
With
+8.0%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 2m
Avg Prosecution
44 currently pending
Career history
1420
Total Applications
across all art units

Statute-Specific Performance

§101
4.5%
-35.5% vs TC avg
§103
16.0%
-24.0% vs TC avg
§102
19.6%
-20.4% vs TC avg
§112
36.5%
-3.5% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1397 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Priority This application was filed 09/18/2023 and is a 371 of PCT/CN22/80829 (03/15/2022) which claims foreign priority to China 2021102887.4 (03/16/2021) and China 202110591611.8 (05/28/2021) and China 202110934860.2 (08/13/2021). Restriction was written 04/30/2026. Election/Restrictions Applicant elected group 1 without traverse in paper dated 06/30/2026. Claims 3, 15 and 16 are withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to a nonelected invention, there being no allowable generic or linking claim. Election was made without traverse in the reply filed on 06/30/2026. Applicant’s election without traverse of group 1 in the reply filed on 06/30/2026 is acknowledged. Claims 1-2, 6-12, 14 and 17-26 will be examined to the extent that they read upon the elected group 1. Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention. Claims 1-2, 6, 9-12, 14, 17-20 and 23-26 are rejected under 35 U.S.C. 102(a)(2) as being anticipated by CN 102781942. CN teaches compounds such as 1790 and 1787 (188/197) that anticipate claims 1, 2,9-12, 14, 17-19 and 23-26. Compound 1790 180/197 is compound #2 of claim 11. Compound on page 179 anticipates claims 1-2, 6, 12, 14, 17-18, 20 and 25-26. CN teaches that the compounds are pharmaceuticals useful to treat insomnia. Claims 1-2, 9-12, 14, 17-19 and 23-26 are rejected under 35 U.S.C. 102(a)(2) as being anticipated by WO2020/100011. WO teaches compounds such as taught in the abstract as orexin receptor modulators that treat conditions such as insomnia and depression. Claims 1-2, 6, 8-10, 12, 14, 17-19 and 23-26 are rejected under 35 U.S.C. 102(a)(2) as being anticipated by US Patent 9586962 Letavic. Letavic teaches compounds such as #433 c253 and #431 C250 as orexin receptor modulators that treat insomnia. Claim Objections Claims 7 and 21-22 are objected to because of the following informalities: These claims depend from a rejected base claim but would be allowable in rewritten in independent form with all intervening limitations. Appropriate correction is required. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to D MARGARET M SEAMAN whose telephone number is (571)272-0694. The examiner can normally be reached M-F 8am-4pm Eastern. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Andrew Kosar can be reached at 571-272-0913. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /D MARGARET M SEAMAN/Primary Examiner, Art Unit 1625
Read full office action

Prosecution Timeline

Sep 18, 2023
Application Filed
Jul 28, 2026
Non-Final Rejection mailed — §102 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

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4y 0m to grant Granted Jul 28, 2026
Patent 12692276
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Patent 12686665
BICYCLIC FUSED RING DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
2y 3m to grant Granted Jul 21, 2026
Patent 12679828
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3y 1m to grant Granted Jul 14, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
77%
Grant Probability
85%
With Interview (+8.0%)
2y 2m (~0m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1397 resolved cases by this examiner. Grant probability derived from career allowance rate.

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