Prosecution Insights
Last updated: August 06, 2026
Application No. 18/552,305

PREVENTION AND TREATMENT OF CORONAVIRUS INFECTION

Final Rejection §102
Filed
Sep 25, 2023
Priority
Mar 24, 2021 — provisional 63/165,542 +1 more
Examiner
ROZOF, TIMOTHY R
Art Unit
1625
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Anavex Life Scences Corp.
OA Round
2 (Final)
73%
Grant Probability
Favorable
3-4
OA Rounds
0m
Est. Remaining
97%
With Interview

Examiner Intelligence

Grants 73% — above average
73%
Career Allowance Rate
699 granted / 962 resolved
+12.7% vs TC avg
Strong +24% interview lift
Without
With
+23.9%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 0m
Avg Prosecution
54 currently pending
Career history
994
Total Applications
across all art units

Statute-Specific Performance

§101
2.4%
-37.6% vs TC avg
§103
21.6%
-18.4% vs TC avg
§102
32.5%
-7.5% vs TC avg
§112
25.7%
-14.3% vs TC avg
Black line = Tech Center average estimate • Based on career data from 962 resolved cases

Office Action

§102
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . DETAILED ACTION This is a response to Applicant’s communication filed on June 5, 2026. Application No. 18/552,305, is a 371 of PCT/US2022/021791, filed March 24, 2022, and claims the benefit of U.S. Provisional application No. 63/165,542, filed March 24, 2021. In a preliminary amendment filed March 7, 2026, Applicant cancelled claims 8-19, 26, 28, and 30; and added new claims 33-35. Claims 1-7, 20-25, 27, 29, and 31-35 are pending. Rejections Withdrawn The rejection of claims 1-7, 20-25, 27, 29, and 31-35 under 35 U.S.C. 112(a) as failing to comply with the enablement requirement, is withdrawn in view of Applicant’s June 5, 2026, Amendment & Remarks. The rejection of claims 1-4, 33 and 35 under 35 U.S.C. 102(a)(1) as being anticipated by Missling, U.S. Patent No. 10,195,192, is withdrawn in view of Applicant’s June 5, 2026, Amendment & Remarks. Rejection Maintained Claim Rejections - 35 USC § 102(a)(1) The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. The rejection of claims 5-7, 20-25, 27, 29, 31, 32, and 34, under 35 U.S.C. 102(a)(1) as being anticipated by Missling, U.S. Patent No. 10,195,192, is maintained for reasons made of record. Applicant argues that the prior art does not expressly disclose any coronavirus-related treatment method. Applicant’s argument is fully considered and is not persuasive. Independent claim 5 is drawn to a method of treating a coronavirus disease; and independent claim 20 is drawn to a method of alleviating or ameliorating symptoms related to a coronavirus disease. Missling discloses AV1066 as therapeutic treatment for visceral and neuropathic pain. Missling discloses treating visceral pain that includes visceral pain resulting from inflammation caused by an infection. Id., Col. 2, lns. 3-11. According, at least with respect to treating pain associated with coronavirus disease; and alleviating or ameliorating persistent pain (see claim 21), Missling reads on the claims of the present invention. Conclusion Claims 1-4, 33, and 35 are allowed. Claims 5-7, 20-25, 27, 29, 31, 32, and 34 are not allowed. THIS ACTION IS MADE FINAL. Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Contact Information Any inquiry concerning this communication or earlier communications from the examiner should be directed to TIMOTHY R ROZOF whose telephone number is (571)270-5992. The examiner can normally be reached Monday - Friday, 9:00 a.m. -5:00 p.m.. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Andrew Kosar can be reached at (571) 272-0913. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /TIMOTHY R ROZOF/Primary Examiner, Art Unit 1625
Read full office action

Prosecution Timeline

Sep 25, 2023
Application Filed
Jun 02, 2025
Response after Non-Final Action
Mar 11, 2026
Non-Final Rejection mailed — §102
Jun 05, 2026
Response Filed
Jul 21, 2026
Final Rejection mailed — §102 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12698278
PREPARATION OF SUBSTITUTED 1,2-DIAMINOHETEROCYCLIC COMPOUND DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS
2y 8m to grant Granted Aug 04, 2026
Patent 12691106
TREATING REFRACTIVE DISORDERS BY TARGETING PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) SIGNALING PATHWAY
3y 1m to grant Granted Jul 28, 2026
Patent 12679843
PYRROLOPYRIMIDINE AMINES AS COMPLEMENT INHIBITORS
2y 10m to grant Granted Jul 14, 2026
Patent 12661359
THERAPEUTIC COMBINATIONS OF ROSUVASTATIN AND RESMETIROM FOR THE TREATMENT OF LIVER DISORDERS OR LIPID DISORDERS
2y 10m to grant Granted Jun 23, 2026
Patent 12662462
SALTS OF PYRIDINYLMETHYLENEPIPERIDINE DERIVATIVES AND USES THEREOF
2y 12m to grant Granted Jun 23, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.
Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

3-4
Expected OA Rounds
73%
Grant Probability
97%
With Interview (+23.9%)
2y 0m (~0m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 962 resolved cases by this examiner. Grant probability derived from career allowance rate.

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month