Prosecution Insights
Last updated: April 19, 2026
Application No. 18/552,784

PREPARATION METHOD FOR BICYCLIC COMPOUND AND APPLICATION AS ANTIFUNGAL AGENT

Non-Final OA §112
Filed
Sep 27, 2023
Examiner
HEASLEY, MEGHAN CHRISTINE
Art Unit
1626
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Jiangxi Jemincare Group Co. Ltd.
OA Round
1 (Non-Final)
76%
Grant Probability
Favorable
1-2
OA Rounds
3y 1m
To Grant
99%
With Interview

Examiner Intelligence

Grants 76% — above average
76%
Career Allow Rate
83 granted / 109 resolved
+16.1% vs TC avg
Strong +34% interview lift
Without
With
+33.6%
Interview Lift
resolved cases with interview
Typical timeline
3y 1m
Avg Prosecution
35 currently pending
Career history
144
Total Applications
across all art units

Statute-Specific Performance

§101
1.8%
-38.2% vs TC avg
§103
33.3%
-6.7% vs TC avg
§102
18.4%
-21.6% vs TC avg
§112
27.2%
-12.8% vs TC avg
Black line = Tech Center average estimate • Based on career data from 109 resolved cases

Office Action

§112
Detailed Action Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Status of the Claims Claims 1 and 17-35 are pending. Claims 1, 17-24, and 28-32 are allowable. Claims 25-27 are rejected. Claims 33-35 are objected to. Priority This is a 35 U.S.C. 371 National Stage Filing of International Application No. PNG media_image1.png 19 204 media_image1.png Greyscale , which claims priority under 35 U.S.C. 119(a-d) to PNG media_image2.png 98 221 media_image2.png Greyscale . Receipt is acknowledged of papers submitted under 35 U.S.C. 119(a)-(d). Information Disclosure Statement The Information Disclosure Statement submitted on 12/29/2023 was considered by the Examiner. Claim Objections Claim 33 is objected to because of the following informalities: There should be commas between each structure and an “and” between the last two structures. Claim 35 is also objected to for depending from an objected to claim and not remedying the deficiencies. Appropriate correction is required. Claim 34 is objected to because of the following informalities: There should be commas between each structure and an “and” between the last two structures. Appropriate correction is required. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(d): (d) REFERENCE IN DEPENDENT FORMS.—Subject to subsection (e), a claim in dependent form shall contain a reference to a claim previously set forth and then specify a further limitation of the subject matter claimed. A claim in dependent form shall be construed to incorporate by reference all the limitations of the claim to which it refers. The following is a quotation of pre-AIA 35 U.S.C. 112, fourth paragraph: Subject to the following paragraph [i.e., the fifth paragraph of pre-AIA 35 U.S.C. 112], a claim in dependent form shall contain a reference to a claim previously set forth and then specify a further limitation of the subject matter claimed. A claim in dependent form shall be construed to incorporate by reference all the limitations of the claim to which it refers. Claims 25-27 are rejected under 35 U.S.C. 112(d) or pre-AIA 35 U.S.C. 112, 4th paragraph, as being of improper dependent form for failing to further limit the subject matter of the claim upon which it depends, or for failing to include all the limitations of the claim upon which it depends. Claim 25 depends from claim 24 and claim 25 includes definitions for “Rc” that are broader than claim 24. For example, “Rc” may be: PNG media_image3.png 23 328 media_image3.png Greyscale , which does not correctly depend from claim 24. Here is the instant claim 24 definition for “Rc” on p. 12: PNG media_image4.png 92 738 media_image4.png Greyscale . Examiner recommends correcting claim 25, “Rc” definition, to properly depend from the definition laid out in claim 24. Claim 26 ultimately depends from claim 24 and claim 26 includes definitions for “Rc” that are broader than claim 24. For example, “Rc” may be: PNG media_image5.png 25 332 media_image5.png Greyscale , which does not correctly depend from claim 24. Examiner recommends correcting claim 26, “Rc” definition, to properly depend from the definition laid out in claim 24. Claim 27 ultimately depends from claim 24 and claim 27 includes definitions for “Rc” that are different than claim 24. For example, “Rc” may be: PNG media_image6.png 97 67 media_image6.png Greyscale , which does not correctly depend from claim 24. Examiner recommends correcting claim 27, “Rc” definition, to properly depend from the definition laid out in claim 24. Applicant may cancel the claim(s), amend the claim(s) to place the claim(s) in proper dependent form, rewrite the claim(s) in independent form, or present a sufficient showing that the dependent claim(s) complies with the statutory requirements. Closest Prior Art Claims 1, 17-24, and 28-32 are allowable. The closest prior art is WO2008142986. WO2008142986 discloses the following bridged compound at the end of claim 1: PNG media_image7.png 159 258 media_image7.png Greyscale , which differs from a compound of instant formula (I): PNG media_image8.png 148 295 media_image8.png Greyscale in multiple locations and connectivity. For example, the prior art compound does not have two aromatic rings, representing instant rings A and B. Therefore, the prior art does not provide motivation for, nor render obvious, the instant claims. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to MEGHAN C HEASLEY whose telephone number is (571)270-0785. The examiner can normally be reached Monday - Friday 8:30-4:30 PM. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Amy Clark can be reached at 571-272-1310. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /MEGHAN C HEASLEY/Examiner, Art Unit 1626
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Prosecution Timeline

Sep 27, 2023
Application Filed
Feb 08, 2026
Non-Final Rejection — §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
76%
Grant Probability
99%
With Interview (+33.6%)
3y 1m
Median Time to Grant
Low
PTA Risk
Based on 109 resolved cases by this examiner. Grant probability derived from career allow rate.

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