Prosecution Insights
Last updated: April 19, 2026
Application No. 18/557,370

DESFERRIOXAMINES AND COMPOSITION CONTAINING UV LIGHT PROTECTION FILTERS

Non-Final OA §103
Filed
Oct 26, 2023
Examiner
KIM, DANIELLE A
Art Unit
1613
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Evonik Operations GmbH
OA Round
1 (Non-Final)
37%
Grant Probability
At Risk
1-2
OA Rounds
3y 8m
To Grant
95%
With Interview

Examiner Intelligence

Grants only 37% of cases
37%
Career Allow Rate
30 granted / 82 resolved
-23.4% vs TC avg
Strong +59% interview lift
Without
With
+58.6%
Interview Lift
resolved cases with interview
Typical timeline
3y 8m
Avg Prosecution
67 currently pending
Career history
149
Total Applications
across all art units

Statute-Specific Performance

§101
1.3%
-38.7% vs TC avg
§103
70.0%
+30.0% vs TC avg
§102
6.5%
-33.5% vs TC avg
§112
15.1%
-24.9% vs TC avg
Black line = Tech Center average estimate • Based on career data from 82 resolved cases

Office Action

§103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Priority The instant application was filed 26 October 2023 and is the national stage entry of PCT/EP2022/060388 filed 20 April 2022. The Applicant claims priority to foreign document EP21170621.3 filed 27 April 2021. An English copy of the foreign documented has not been provided. Therefore, the effective filing date of the instant application is 20 April 2022. Election/Restrictions Claims 9-11, 18-20 are withdrawn from further consideration pursuant to 37 CFR 1.142(b), as being drawn to a nonelected invention, there being no allowable generic or linking claim. Applicant timely traversed the restriction (election) requirement in the reply filed on 28 November 2025. Applicant's election with traverse of Group I in the reply filed on 28 November 2025 is acknowledged. The traversal is on the ground(s) that there is no analysis under MPEP 1893.03(d) and there is no search burden. This is not found persuasive because one of ordinary skill in the art would have been motivated to use Weinert’s teaching of using a UV filter agent and a complexing agent to improve the composition taught in Lanzendoerfer. Weinert’s teaching includes EDTA, an iron chelator, as a complexing agent in combination with a UV filtering agent (pg. 2, para. 6) that produces this surprising benefit. One of ordinary skill in the art would have been led to use any complexing agent and iron chelator, such as desferrioxamine, with a UV filtering agent with a reasonable expectation of success. Therefore, the groups lack unity of invention. Additionally, the inventions require different fields of search (e.g., searching different classes/subclasses or electronic resources, or employing different search strategies or search queries). Therefore, there is a serious burden in terms of search and examination, as examination of the inventions together necessitates multiple search queries. The requirement is still deemed proper and is therefore made FINAL. Claim Rejections - 35 USC § 103 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. Claim(s) 1, 2, 4-8, 12-17 is/are rejected under 35 U.S.C. 103 as being unpatentable over Lanzendoerfer et al. (DE 10050155 A1; machine translation cited). Lanzendoerfer teaches a cosmetic composition comprising desferrioxamine B (evidenced by instant specification, pg. 1) in an amount of 0.5%, antioxidants, and a UV filter agent, such as methylbenzylidenecamphor (Example 1; entire teaching) or butylmethoxydibenzoylmethane (Example 9), in an amount of 0.1-30% (pg. 5, para. 2), addressing claims, 1, 2, 4, 8, and 12-15. 2-ethylhexyl salicylate and a triazine derivative (pg. 5, para. 4) are examples of suitable UV filter agents, and UVB filters and UVA filters may be combined, which is interpreted as having at least one UV filter agent (pg. 5, paras. 7-8), addressing claims 5-7, 16, and 17. Lanzendoerfer does not teach an exact combination of desferrioxamine and 6-60% of a UV filter agent in claim 1. In regards to selecting the combination of desferrioxamine B and 6-60% of a UV filter agent, “[w]hen a patent simply arranges old elements with each performing the same function it had been known to perform and yields no more than one would expect from such an arrangement, the combination is obvious.” KSR v. Teleflex, 127 S.Ct. 1727, 1740 (2007) (quoting Sakraida v. A.G.Pro, 425 U.S. 273, 282 (1976)). “When the question is whether a patent claiming the combination of elements of prior art is obvious,” the relevant question is “whether the improvement is more than the predictable use of prior art elements according to their established functions.” (Id.). Addressing the issue of obviousness, the Supreme Court noted that the analysis under 35 USC 103 “need not seek out precise teachings directed to the specific subject matter of the challenged claim, for a court can take account of the inferences and creative steps that a person of ordinary skill in the art would employ.” KSR at 1741. The Court emphasized that “[a] person of ordinary skill is… a person of ordinary creativity, not an automaton.” Id. at 1742. Consistent with this reasoning, it would have been obvious to have selected various combinations of various disclosed ingredients from within a prior art disclosure, to arrive at compositions “yielding no more than one would expect from such an arrangement.” Lanzendoerfer teaches compositions comprising desferrioxamine, antioxidants, and UV filtering agents, whereas the claimed invention is directed towards a composition comprising at least one desferrioxamine or acid addition product of desferrioxamine and 6-60% of a UV light protection filter substance. Since Lanzendoerfer teaches the individual components of the claimed composition, it is obvious for one of ordinary skill in the art to select the different combinations of ingredients to arrive at the claimed invention with a reasonable expectation of success. Claim(s) 1-8, 12-17 is/are rejected under 35 U.S.C. 103 as being unpatentable over Lanzendoerfer et al. (DE 10050155 A1; machine translation cited) and Gurtner (WO 2020061474 A1). In regards to claim(s) 1, 2, 4-8, 12-17, Lanzendoerfer, as applied supra, is herein applied in its entirety for its teachings of a cosmetic composition comprising desferrioxamine and a UV filter agent. Lanzendoerfer does not specifically teach an acid addition product of desferrioxamine in claim 3. Gurtner teaches a topical composition comprising iron chelating compounds (abs; entire teaching), such as deferoxamine mesylate (para. 136). Use of pharmaceutically acceptable salts or acid addition salts, such as sulfuric acid, phosphoric acid, or malonic acid (para. 45) are considered safe, non-toxic, have favorable pharmacological activity, and are well-known in the art (para. 51). Since Lanzendoerfer does not specifically teach an acid addition product of desferrioxamine in claim 3, one of ordinary skill in the art would have been motivated to use Gurtner’s teaching with a reasonable expectation of success. Use of an acid addition salt of a drug compound is known and established in the art. Furthermore, a skilled artisan would have been easily led to improve Lanzendoerfer’s teaching for the added benefit of favorable pharmacological activity, safety, and non-toxicity. Generally, it is prima facie obvious to combine or substitute one equivalent component or process for another, each of which is taught by the prior art to be useful for the same purpose (see MPEP 2144.06). Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to Danielle Kim whose telephone number is (571)272-2035. The examiner can normally be reached M-F: 9-5 p.m. PST. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Brian-Yong Kwon can be reached at (571)272-0581. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /D.A.K./Examiner, Art Unit 1613 /ANDREW S ROSENTHAL/Primary Examiner, Art Unit 1613
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Prosecution Timeline

Oct 26, 2023
Application Filed
Jan 26, 2026
Non-Final Rejection — §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
37%
Grant Probability
95%
With Interview (+58.6%)
3y 8m
Median Time to Grant
Low
PTA Risk
Based on 82 resolved cases by this examiner. Grant probability derived from career allow rate.

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