Prosecution Insights
Last updated: October 01, 2026
Application No. 18/562,161

IMPROVED UnaG FLUORESCENT PROTEIN FOR BiFC ASSAYS

Non-Final OA §102
Filed
Nov 17, 2023
Priority
May 17, 2021 — provisional 63/189,370 +2 more
Examiner
MONSHIPOURI, MARYAM
Art Unit
1651
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
The Regents of the University of California
OA Round
1 (Non-Final)
79%
Grant Probability
Favorable
1-2
OA Rounds
0m
Est. Remaining
99%
With Interview

Examiner Intelligence

Grants 79% — above average
79%
Career Allowance Rate
772 granted / 976 resolved
+19.1% vs TC avg
Strong +38% interview lift
Without
With
+37.5%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 2m
Avg Prosecution
33 currently pending
Career history
1005
Total Applications
across all art units

Statute-Specific Performance

§101
2.4%
-37.6% vs TC avg
§103
24.3%
-15.7% vs TC avg
§102
17.0%
-23.0% vs TC avg
§112
37.0%
-3.0% vs TC avg
Black line = Tech Center average estimate • Based on career data from 976 resolved cases

Office Action

§102
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Applicant’s response to restriction requirement filed 7/27/26 is acknowledged. Applicant elected Group I (claims 1-3) without traverse. Applicant also chose SEQ ID NO:3 as an elected species. Claims 10, 12, 15-16, 18, 20, 24 are canceled. Claims 4-9, 11, 13-14, 17, 19, 21-23, 25-27 are hereby withdrawn as drawn to non-elected subject matter. Applicant must rest assured that once the elected invention becomes allowable the examiner will consider methods of making and using Saud product under provisions of re Ochiai. DETAILED ACTION Claims 1-3 are under examination on the merits. SEQ ID NO:1 and SEQ ID NO:2 are hereby rejoined with the elected invention. Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention. Claim 1 is rejected under 35 U.S.C. 102(a)(2) as being anticipated by Nagani et al., “Nagani” (US Patent No. 11,372,007, 6/2022). Nagani teaches (see its SEQ ID NO:12, attached) a chemiluminescent indicator polypeptide displaying an amino acid sequence displaying 96.4% identity to instant SEQ ID NO:1 prior to this invention, anticipating claim 1. Allowable Subject Matter Claims 2-3 appear to be free of prior art. Further, the prior art fails to suggest such specifically claimed products. Hence, said claims are also non-obvious. Any inquiry concerning this communication or earlier communications from the examiner should be directed to MARYAM MONSHIPOURI whose telephone number is (571)272-0932. The examiner can normally be reached full-flex. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Melenie L Gordon can be reached at 571-272-8037. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /MARYAM MONSHIPOURI/Primary Examiner, Art Unit 1651
Read full office action

Prosecution Timeline

Nov 17, 2023
Application Filed
Aug 14, 2026
Examiner Interview (Telephonic)
Aug 18, 2026
Non-Final Rejection mailed — §102 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
79%
Grant Probability
99%
With Interview (+37.5%)
2y 2m (~0m remaining)
Median Time to Grant
Low
PTA Risk
Based on 976 resolved cases by this examiner. Grant probability derived from career allowance rate.

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