Prosecution Insights
Last updated: July 17, 2026
Application No. 18/564,163

NR4A3-DEFICIENT IMMUNE CELLS AND USES THEREOF

Non-Final OA
Filed
Nov 27, 2023
Priority
May 28, 2021 — provisional 63/194,745 +2 more
Examiner
HAMA, JOANNE
Art Unit
Tech Center
Assignee
Lyell Immunopharma Inc.
OA Round
1 (Non-Final)
25%
Grant Probability
At Risk
1-2
OA Rounds
1y 0m
Est. Remaining
64%
With Interview

Examiner Intelligence

Grants only 25% of cases
25%
Career Allowance Rate
65 granted / 259 resolved
-34.9% vs TC avg
Strong +39% interview lift
Without
With
+38.8%
Interview Lift
resolved cases with interview
Typical timeline
3y 8m
Avg Prosecution
26 currently pending
Career history
287
Total Applications
across all art units

Statute-Specific Performance

§101
4.7%
-35.3% vs TC avg
§103
57.3%
+17.3% vs TC avg
§102
8.3%
-31.7% vs TC avg
§112
14.9%
-25.1% vs TC avg
Black line = Tech Center average estimate • Based on career data from 259 resolved cases

Prosecution Timeline

Nov 27, 2023
Application Filed
Jun 05, 2026
Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12648929
COMPOSITIONS AND METHODS FOR PREVENTING AND/OR TREATING FILARIAL DISEASE
5y 3m to grant Granted Jun 09, 2026
Patent 12595300
ANTI-HUMAN P40 PROTEIN DOMAIN ANTIBODY AND USE THEREOF
4y 2m to grant Granted Apr 07, 2026
Patent 12559553
IL-31 MODULATORS FOR TREATING FXR-INDUCED PRURITUS
3y 8m to grant Granted Feb 24, 2026
Patent 12553897
USE OF CIRCULATING INTERLEUKIN-18 FOR PROGNOSTICATING AND TREATING RECURRENCE IN EARLY STAGE NON-SMALL CELL LUNG CANCER
3y 8m to grant Granted Feb 17, 2026
Patent 12168688
ANTIBODIES AND VARIANTS THEREOF AGAINST PD-L1
4y 5m to grant Granted Dec 17, 2024
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
25%
Grant Probability
64%
With Interview (+38.8%)
3y 8m (~1y 0m remaining)
Median Time to Grant
Low
PTA Risk
Based on 259 resolved cases by this examiner. Grant probability derived from career allowance rate.

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