Prosecution Insights
Last updated: October 01, 2026
Application No. 18/573,785

COMPOSITION FOR SUPPRESSING MUSCLE DAMAGE

Final Rejection §103
Filed
Dec 26, 2023
Priority
Jun 25, 2021 — JP PCT/JP2021/024243 +1 more
Examiner
AULAKH, CHARANJIT
Art Unit
1621
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Otsuka Pharmaceutical Co., Ltd.
OA Round
2 (Final)
81%
Grant Probability
Favorable
3-4
OA Rounds
0m
Est. Remaining
66%
With Interview

Examiner Intelligence

Grants 81% — above average
81%
Career Allowance Rate
1441 granted / 1787 resolved
+20.6% vs TC avg
Minimal -14% lift
Without
With
+-14.5%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 0m
Avg Prosecution
61 currently pending
Career history
1817
Total Applications
across all art units

Statute-Specific Performance

§101
3.3%
-36.7% vs TC avg
§103
15.0%
-25.0% vs TC avg
§102
20.5%
-19.5% vs TC avg
§112
43.5%
+3.5% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1787 resolved cases

Office Action

§103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . According to paper filed on July 2, 2026, the applicants have added new claims 11-14. Claims 5-14 are pending in the application. Response to Arguments Applicant's arguments filed July 2, 2026 have been fully considered but they are not persuasive. Regarding obviousness rejection over Hurst’s reference, the applicants argue on page 5 that Hurst does teach using Malvin glycoside but does not teach using Kaempferol glycoside. The examiner agrees with it. However, the claims are directed to using Kaempferol and/or glycoside and therefore, are not directed to using Kaempferol glycoside specifically. It can be any glycoside. Therefore, it would have been obvious to reduce muscle damage using Malvin glycoside with reasonable expectation of success. In regard to obviousness rejection over Ikeda in view of Funes, the applicants argue on page 7 that Ikeda’s teachings of improving physical activity efficiency or reducing fatigue does not suggest intense exercise. The examiner does not agree with this. The applicant’s attention is drawn to page 24, line 3 to page 25, line 9 in Ikeda’s reference where different levels of exercise intensities are clearly defined. Regarding ODP rejection, the examiner also does not agree with applicant’s arguments that it would not have been obvious to reduce muscle damage over claims of PAT 12,048,683 in view of Funes to one skilled in the art. Conclusion The obviousness rejection of claims 5-14 under 35 U.S.C. 103(a) over Hurst’s reference is maintained. The obviousness rejection of claims 5-14 under 35 U.S.C. 103(a) over Ikeda in view of Funes reference is maintained. The ODP rejection over claims of PAT 12,048,683 in view of Funes reference is maintained. THIS ACTION IS MADE FINAL. Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to CHARANJIT AULAKH whose telephone number is (571)272-0678. The examiner can normally be reached Monday-Friday 7:00-3:30. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Clinton A Brooks can be reached at 571-270-7682. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /CHARANJIT AULAKH/ Primary Examiner, Art Unit 1621
Read full office action

Prosecution Timeline

Dec 26, 2023
Application Filed
Mar 03, 2026
Non-Final Rejection mailed — §103
Jul 02, 2026
Response Filed
Jul 16, 2026
Final Rejection mailed — §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
81%
Grant Probability
66%
With Interview (-14.5%)
2y 0m (~0m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 1787 resolved cases by this examiner. Grant probability derived from career allowance rate.

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