Prosecution Insights
Last updated: April 19, 2026
Application No. 18/576,140

METHOD FOR PRODUCING A SECTION RIBBON FROM A SAMPLE BLOCK USING A MICROTOME, METHOD FOR PREPARING A MICROSCOPIC SAMPLE FOR EXAMINATION IN AN ELECTRON MICROSCOPE, MICROTOME AND EMBEDDING MOULD FOR USE THEREIN

Non-Final OA §102
Filed
Jan 03, 2024
Examiner
FLORES SANCHEZ, OMAR
Art Unit
3724
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Leica Mikrosysteme GmbH
OA Round
1 (Non-Final)
74%
Grant Probability
Favorable
1-2
OA Rounds
2y 10m
To Grant
88%
With Interview

Examiner Intelligence

Grants 74% — above average
74%
Career Allow Rate
1262 granted / 1712 resolved
+3.7% vs TC avg
Moderate +14% lift
Without
With
+14.3%
Interview Lift
resolved cases with interview
Typical timeline
2y 10m
Avg Prosecution
19 currently pending
Career history
1731
Total Applications
across all art units

Statute-Specific Performance

§103
39.1%
-0.9% vs TC avg
§102
31.5%
-8.5% vs TC avg
§112
25.2%
-14.8% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1712 resolved cases

Office Action

§102
DETAILED ACTION Election/Restrictions Applicant’s election with traverse of Species III in the reply filed on 10/1/25 is acknowledged. Drawings The drawings are objected to under 37 CFR 1.83(a). The drawings must show every feature of the invention specified in the claims. Therefore, the precursor sample block, joint precursor regions, a tear tab, and a tear track must be shown or the feature(s) canceled from the claim(s). No new matter should be entered. Corrected drawing sheets in compliance with 37 CFR 1.121(d) are required in reply to the Office action to avoid abandonment of the application. Any amended replacement drawing sheet should include all of the figures appearing on the immediate prior version of the sheet, even if only one figure is being amended. The figure or figure number of an amended drawing should not be labeled as “amended.” If a drawing figure is to be canceled, the appropriate figure must be removed from the replacement sheet, and where necessary, the remaining figures must be renumbered and appropriate changes made to the brief description of the several views of the drawings for consistency. Additional replacement sheets may be necessary to show the renumbering of the remaining figures. Each drawing sheet submitted after the filing date of an application must be labeled in the top margin as either “Replacement Sheet” or “New Sheet” pursuant to 37 CFR 1.121(d). If the changes are not accepted by the examiner, the applicant will be notified and informed of any required corrective action in the next Office action. The objection to the drawings will not be held in abeyance. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 1-2, 8-10, and 16-19 is/are rejected under 35 U.S.C. 102(a)(1) as being disclosed by Hess et al. (2015/0135917). Hess et al. discloses the method/invention including the step of: producing a section ribbon from a sample block (see Fig. 6), the method comprising: producing a first part ribbon of the section ribbon (see Fig. 11, 18-21) from a first surface region of the sample block using a microtome comprising a blade 106, the first part ribbon having one or more first sections of the sample block and producing a second part ribbon (see Fig. 11, para. 0094) of the section ribbon from a second surface region of the sample block using the microtome comprising the blade, the second part ribbon having one or more second sections of the sample block, the second surface region being different from the first surface region (see Fig. 11), and retracting the sample block is retracted from the blade between the producing of the first part ribbon and the producing of the second part ribbon (see Fig. 18-19); wherein the first surface region and the second surface region are provided as disjoint surface regions (see Fig. 11, para. 0094) of the sample block; producing the sample block, wherein the first surface region 1002 and the second surface region 1002’ are provided as joint surface regions of the sample block (see Fig. 10); wherein the sample block is repositioned in one or more directions (see Fig. 13 and 18-19) relative to the blade between the producing of the first part ribbon and the producing of the second part ribbon; an ultra-microtome (para. 0004), and wherein the one or more first sections (see Fig. 13, para. 0094) and the one or more second sections (see Fig. 13, para. 0094) are produced as ultrathin sections; A microtome 100 configured to perform a method according to any of the preceding claim 1; a control unit 148, an undivided inner space (see Fig. 10), a first compartment and a second compartment, the first compartment (the area covered by sample 1002) and the second compartment (the area covered by sample 1002’) extending from and being contiguous with the undivided inner space. Allowable Subject Matter Claim 11 allowed. Claims 3-7, 12-15, and 20-27 are objected to as being dependent upon a rejected base claim, but would be allowable if rewritten in independent form including all of the limitations of the base claim and any intervening claims. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to OMAR FLORES SANCHEZ whose telephone number is (571)272-4507. The examiner can normally be reached Monday thru Thursday8:00-4:00 pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Adam Eiseman can be reached at 571-270-3818. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /OMAR FLORES SANCHEZ/Primary Examiner, Art Unit 3724
Read full office action

Prosecution Timeline

Jan 03, 2024
Application Filed
Feb 13, 2026
Non-Final Rejection — §102 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
74%
Grant Probability
88%
With Interview (+14.3%)
2y 10m
Median Time to Grant
Low
PTA Risk
Based on 1712 resolved cases by this examiner. Grant probability derived from career allow rate.

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