Last updated: July 17, 2026

Application No. 18/577,158

PH-RESPONSIVE LIPID DERIVATIVE

Non-Final OA

Filed

Jan 05, 2024

Priority

Jul 07, 2021 — JP 2021-113189 +1 more

Examiner

SAMSELL, RILLA MARIE

Art Unit

1624

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Tokyo Institute of Technology

OA Round

1 (Non-Final)

Interview Optional

— +14.7% interview lift. Interview lift (+14.7%) is below the 15.0% threshold. A written response is recommended.

Based on 76 resolved cases, 2023–2026

Examiner Intelligence

SAMSELL, RILLA MARIE View full profile →

Grants 72% — above average

Career Allowance Rate

55 granted / 76 resolved

+12.4% vs TC avg

Moderate +15% lift

Without

With

+14.7%

Interview Lift

resolved cases with interview

Typical timeline

3y 2m

Avg Prosecution

38 currently pending

Career history

113

Total Applications

across all art units

Statute-Specific Performance

§101

1.3%

-38.7% vs TC avg

§103

35.3%

-4.7% vs TC avg

§102

13.4%

-26.6% vs TC avg

§112

25.0%

-15.0% vs TC avg

Black line = Tech Center average estimate • Based on career data from 76 resolved cases

Prosecution Timeline

Jan 05, 2024

Application Filed

Jun 02, 2026

Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

18/157,397

Patent 12679838

AROMATIC COMPOUND AND APPLICATION THEREOF IN ANTITUMOR DRUG

3y 5m to grant Granted Jul 14, 2026

18/252,261

Patent 12679848

PLASMA KALLIKREIN INHIBITORS

3y 2m to grant Granted Jul 14, 2026

17/920,679

Patent 12673927

SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION

3y 8m to grant Granted Jul 07, 2026

17/909,429

Patent 12668589

N-FORMAMIDOPYRAZOLINE DERIVATIVE AS P2X3 RECEPTOR ANTAGONIST AND USE THEREOF

3y 9m to grant Granted Jun 30, 2026

17/615,056

Patent 12637451

AMINO QUINAZOLINE DERIVATIVES AS P2X3 INHIBITORS

4y 5m to grant Granted May 26, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

1-2

Expected OA Rounds

72%

Grant Probability

87%

With Interview (+14.7%)

3y 2m (~8m remaining)

Median Time to Grant

Low

PTA Risk

Based on 76 resolved cases by this examiner. Grant probability derived from career allowance rate.