Prosecution Insights
Last updated: July 17, 2026
Application No. 18/637,382

DEUTERATED NUCLEOSIDE COMPOUNDS AND USE THEREOF

Non-Final OA §112
Filed
Apr 16, 2024
Priority
May 17, 2022 — CN 202210548373.7 +5 more
Examiner
LEESER, ERICH A
Art Unit
1622
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Medshine Discovery Inc.
OA Round
1 (Non-Final)
82%
Grant Probability
Favorable
1-2
OA Rounds
0m
Est. Remaining
95%
With Interview

Examiner Intelligence

Grants 82% — above average
82%
Career Allowance Rate
782 granted / 958 resolved
+21.6% vs TC avg
Moderate +13% lift
Without
With
+13.4%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 1m
Avg Prosecution
30 currently pending
Career history
980
Total Applications
across all art units

Statute-Specific Performance

§101
0.8%
-39.2% vs TC avg
§103
17.7%
-22.3% vs TC avg
§102
22.0%
-18.0% vs TC avg
§112
29.3%
-10.7% vs TC avg
Black line = Tech Center average estimate • Based on career data from 958 resolved cases

Office Action

§112
DETAILED ACTION This action is in response to Applicant’s submission dated June 16, 2026, in which the species of Compound 3 was elected with traverse as well as the invention of Group I. Election/Restriction Applicant traverses the outstanding restriction requirement; however, Examiner hereby withdraws it. Information Disclosure Statement The references contained in the IDS dated October 3, 2024 and June 16, 2026 are made of record. Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. Claim 8 is rejected under 35 U.S.C. 112(b), as being indefinite for failing to particularly point out and distinctly claim the subject matter which applicant regards as the invention. The phrase “treating diseases related to RNA-dependent RNA polymerase inhibitor” is recited. This expression is vague and indefinite because the claim does not explain how the diseases are related to RNA-dependent RNA polymerase inhibitor in the claim. Examiner recommends putting the specific names for the diseases related to RNA-dependent RNA polymerase inhibitor in the claim itself. Allowable Subject Matter Claim 1-7 are patentable over Zhang, et al., US2024/0317754, which teaches anti-viral compounds: PNG media_image1.png 204 334 media_image1.png Greyscale , see p. 27, paragraph [0220]. The compounds of the reference possess hydrogen where deuterium is taught instantly plus ATV013 teaches phenyl where the equivalent position in the compounds of the instant application cannot be phenyl. Therefore, the claims are free of prior art. Conclusion Any inquiry concerning this communication or earlier communications from the Examiner should be directed to ERICH A LEESER whose telephone number is (571) 272-9932. The Examiner can normally be reached Monday through Friday from 10-6 PST, M-F. PST. If attempts to reach the Examiner by telephone are unsuccessful, the Examiner’s supervisor, Mr. James Alstrum-Acevedo can be reached at (571) 272-5548. The fax number for the organization where this application is assigned is 571-273-8300. Information regarding the status of an application may be obtained from the Patent Application Information Retrieval (PAIR) system. Status information for published applications may be obtained from either Private PAIR or Public PAIR. Status information for unpublished applications is available through Private PAIR only. For more information about the PAIR system, see http://pair-direct.uspto.gov. Should you have questions on access to the Private PAIR system, contact the Electronic Business Center (EBC) toll-free at 866-217-9197. If you would like assistance from a USPTO Customer Service Representative or access to the automated information system, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /ERICH A LEESER/Primary Examiner, Art Unit 1622 United States Patent and Trademark Office Tel. No.: (571) 272-9932
Read full office action

Prosecution Timeline

Apr 16, 2024
Application Filed
Jun 29, 2026
Non-Final Rejection mailed — §112 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
82%
Grant Probability
95%
With Interview (+13.4%)
2y 1m (~0m remaining)
Median Time to Grant
Low
PTA Risk
Based on 958 resolved cases by this examiner. Grant probability derived from career allowance rate.

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