Prosecution Insights
Last updated: July 17, 2026
Application No. 18/687,347

Process for Synthesizing Naphthyridine Derivatives and Intermediates Thereof

Non-Final OA
Filed
Feb 28, 2024
Priority
Aug 30, 2021 — provisional 63/238,337 +3 more
Examiner
VALENROD, YEVGENY
Art Unit
1628
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Amgen Inc.
OA Round
1 (Non-Final)
72%
Grant Probability
Favorable
1-2
OA Rounds
1m
Est. Remaining
98%
With Interview

Examiner Intelligence

Grants 72% — above average
72%
Career Allowance Rate
734 granted / 1012 resolved
+12.5% vs TC avg
Strong +26% interview lift
Without
With
+25.5%
Interview Lift
resolved cases with interview
Typical timeline
2y 6m
Avg Prosecution
38 currently pending
Career history
1049
Total Applications
across all art units

Statute-Specific Performance

§101
1.1%
-38.9% vs TC avg
§103
48.6%
+8.6% vs TC avg
§102
13.4%
-26.6% vs TC avg
§112
7.7%
-32.3% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1012 resolved cases

Prosecution Timeline

Feb 28, 2024
Application Filed
Apr 22, 2026
Non-Final Rejection mailed (current)

Precedent Cases

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3y 0m to grant Granted Mar 31, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
72%
Grant Probability
98%
With Interview (+25.5%)
2y 6m (~1m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1012 resolved cases by this examiner. Grant probability derived from career allowance rate.

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