Prosecution Insights
Last updated: August 16, 2026
Application No. 18/689,319

ACRIDINE COMPOUND

Non-Final OA §102
Filed
Mar 05, 2024
Priority
Sep 06, 2021 — JP 2021-144882 +1 more
Examiner
MAHLUM, JONATHAN DAVIS
Art Unit
1625
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Otsuka Pharmaceutical Co., Ltd.
OA Round
1 (Non-Final)
52%
Grant Probability
Moderate
1-2
OA Rounds
1y 5m
Est. Remaining
72%
With Interview

Examiner Intelligence

Grants 52% of resolved cases
52%
Career Allowance Rate
17 granted / 33 resolved
-8.5% vs TC avg
Strong +21% interview lift
Without
With
+20.8%
Interview Lift
resolved cases with interview
Typical timeline
3y 11m
Avg Prosecution
47 currently pending
Career history
89
Total Applications
across all art units

Statute-Specific Performance

§101
2.7%
-37.3% vs TC avg
§103
36.9%
-3.1% vs TC avg
§102
17.5%
-22.5% vs TC avg
§112
23.5%
-16.5% vs TC avg
Black line = Tech Center average estimate • Based on career data from 33 resolved cases

Office Action

§102
Detailed Action The present office action is in response to the response filed on 20 May 2026. Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Status Claims 1-6 of the pending application have been examined on the merits. Claims 7-8 are withdrawn (see “Response to Applicant Election” below). Priority Applicants identify the instant application, Serial #: 18/689,319, filed 05 Mar 2024, as a National Stage Entry of International Application #: PCT/JP2022/033207, filed 05 Sep 2022, which claims foreign priority from Foreign Application #: JP2021-144882, filed 06 Sep 2021. Information Disclosure Statement The information disclosure statement(s) (IDS) submitted on 05 Mar 2024, 22 Jul 2025, and 04 Mar 2026 is in compliance with the provisions of 37 CFR 1.97. Accordingly, the information disclosure statement is being considered by the examiner. The listing of references in the specification is not a proper information disclosure statement. 37 CFR 1.98(b) requires a list of all patents, publications, or other information submitted for consideration by the Office, and MPEP § 609.04(a) states, "the list may not be incorporated into the specification but must be submitted in a separate paper." Therefore, unless the references have been cited by the examiner on form PTO-892, they have not been considered. Response to Applicant Election Applicant’s election without traverse of Group I, claims 1-6, in the reply filed on 20 May 2026 is acknowledged. Applicant further elected Example 1 as the species of formula I: PNG media_image1.png 192 255 media_image1.png Greyscale No art was found after a search for the elected species. Examiner extended the Markush search to encompass the following species which reads on claims 1-6: PNG media_image2.png 171 159 media_image2.png Greyscale Where X is perchlorate ion. Prior art was returned after a search for the species. Claims 7-8 are withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to a nonelected group, there being no allowable generic or linking claim. Election was made without traverse in the reply filed on 20 May 2026. Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 1-6 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Yan et al. (CCS Chem, 2021, 3:317-325; provided in IDS 03/05/24), hereinafter Yan. The instantly elected claims are drawn to compounds of formula [I]: PNG media_image3.png 162 299 media_image3.png Greyscale Examiner has expanded the Markush search to include the following species: PNG media_image4.png 165 142 media_image4.png Greyscale where X is perchlorate. The species reads on claims 1-6. Claim 6 is further directed towards compounds which are photoredox catalysts. Yan teaches compound S3 (Supplemental Information, S22): PNG media_image5.png 190 141 media_image5.png Greyscale Compound S3 anticipates the instant claims. The ability of Compound S3 to be a photoredox catalyst is inherent and so claim 6 is also rejected by compound S3. See MPEP § 2112(I)-(II). Conclusion No claim is allowed. Correspondence Any inquiry concerning this communication or earlier communications from the examiner should be directed to Jonathan D. Mahlum whose telephone number is (703)756-4691. The examiner can normally be reached 8:30 AM - 5:00 PM ET, M-F. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Andrew Kosar can be reached at (571) 272-0913. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /J.D.M./Examiner, Art Unit 1625 /Andrew D Kosar/Supervisory Patent Examiner, Art Unit 1625
Read full office action

Prosecution Timeline

Mar 05, 2024
Application Filed
Aug 05, 2026
Non-Final Rejection mailed — §102 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
52%
Grant Probability
72%
With Interview (+20.8%)
3y 11m (~1y 5m remaining)
Median Time to Grant
Low
PTA Risk
Based on 33 resolved cases by this examiner. Grant probability derived from career allowance rate.

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