Prosecution Insights
Last updated: April 19, 2026
Application No. 18/692,114

SMALL MOLECULE COMPOUNDS HAVING NAPHTHYLAMINE STRUCTURE AND APPLICATION THEREOF

Non-Final OA §102
Filed
Mar 14, 2024
Examiner
HUTTER, GILLIAN A
Art Unit
1625
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Hangzhou Phecdamed Co. Ltd.
OA Round
1 (Non-Final)
55%
Grant Probability
Moderate
1-2
OA Rounds
3y 0m
To Grant
99%
With Interview

Examiner Intelligence

Grants 55% of resolved cases
55%
Career Allow Rate
62 granted / 113 resolved
-5.1% vs TC avg
Strong +45% interview lift
Without
With
+44.9%
Interview Lift
resolved cases with interview
Typical timeline
3y 0m
Avg Prosecution
49 currently pending
Career history
162
Total Applications
across all art units

Statute-Specific Performance

§101
2.4%
-37.6% vs TC avg
§103
39.5%
-0.5% vs TC avg
§102
21.1%
-18.9% vs TC avg
§112
20.4%
-19.6% vs TC avg
Black line = Tech Center average estimate • Based on career data from 113 resolved cases

Office Action

§102
Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Current Status of 18/692,114 This Office Action is responsive to the amended claims of 9/11/2024. Claim 9 has been examined on the merits. Priority This Application is a national stage entry of PCT/CN2022/119825 and also claims foreign priority to CN202111108417.6. There is also a continuation, which is now a US patent 12151999. Receipt is acknowledged of certified copies of papers required by 37 CFR 1.55. A review of the file wrapper indicates a foreign language priority document. However, since it is not in English, a judgement cannot be made as to whether it supports the instant claims, which is required to perfect foreign priority. The conditions of 35 U.S.C. § 119(a)-(d) or (f) are not met. Therefore, the effective filing date for the instant claims is the international filing date of 9/20/2022. Information Disclosure Statement The information disclosure statements (IDS), submitted on 9/11/2024 and 10/08/2024, and 02/03/2026, are in compliance with the provisions of 37 CFR 1.97. Accordingly, the information disclosure statement is being considered by the examiner. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 9 is rejected under 35 U.S.C. 102(a)(1) as being anticipated by ACS (American Chemical Society, Chemical Abstract Service, RN: 1204290-89-0, First made available to the public January 29, 2010). ACS anticipates compound I-13-2, shown below. PNG media_image1.png 617 786 media_image1.png Greyscale . Claim(s) 9 is rejected under 35 U.S.C. 102(a)(1) as being anticipated by LAWRENCE (WO 2010005534 A2). LAWRENCE anticipates a compound with a CAS# of 1204290-89-0 (page 109; Compound 5.2.30). LAWRENCE anticipates pharmaceutically acceptable salts of formula I (page 3), which Compound 5.2.30 is a compound of Formula I. LAWRENCE anticipates stereoisomers of formula I (page 19). This anticipates claim 9. Conclusion Claim 9 is rejected. US patent 12151999 is not a statutory double patent because reference claims have a proviso that does not allow for the instant compound. Any inquiry concerning this communication or earlier communications from the examiner should be directed to GILLIAN A HUTTER whose telephone number is (571)272-6323. The examiner can normally be reached M-F 7:30-5. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Andrew Kosar can be reached at 571-272-0913. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /G.A.H./ Examiner, Art Unit 1625 /Andrew D Kosar/Supervisory Patent Examiner, Art Unit 1625
Read full office action

Prosecution Timeline

Mar 14, 2024
Application Filed
Feb 06, 2026
Non-Final Rejection — §102 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
55%
Grant Probability
99%
With Interview (+44.9%)
3y 0m
Median Time to Grant
Low
PTA Risk
Based on 113 resolved cases by this examiner. Grant probability derived from career allow rate.

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