Office Action Predictor
Last updated: April 16, 2026
Application No. 18/699,096

CELL IMAGE ANALYSIS SYSTEM

Non-Final OA §102
Filed
Apr 05, 2024
Examiner
HUYNH, VAN D
Art Unit
2665
Tech Center
2600 — Communications
Assignee
Shimadzu Corporation
OA Round
1 (Non-Final)
87%
Grant Probability
Favorable
1-2
OA Rounds
2y 4m
To Grant
99%
With Interview

Examiner Intelligence

Grants 87% — above average
87%
Career Allow Rate
630 granted / 721 resolved
+25.4% vs TC avg
Strong +25% interview lift
Without
With
+24.8%
Interview Lift
resolved cases with interview
Typical timeline
2y 4m
Avg Prosecution
25 currently pending
Career history
746
Total Applications
across all art units

Statute-Specific Performance

§101
8.8%
-31.2% vs TC avg
§103
31.9%
-8.1% vs TC avg
§102
31.0%
-9.0% vs TC avg
§112
14.2%
-25.8% vs TC avg
Black line = Tech Center average estimate • Based on career data from 721 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claim Objections Claims 10-11 are objected to because of the following informalities: Claims 10-11 recite abbreviation “CSV” where full text is not present. Applicant is advised to write full text first and then abbreviation in parenthesis at least once [i.e. media access control (MAC)]. Examiner suggests replacing “CSV” in claim 10 with --Comma Separated Value (CSV)--. Appropriate correction is required. Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 1-12 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Wilshire et al., “FlowJo Basic Tutorial”. Regarding claim 1, Wilshire discloses a cell image analysis system comprising: a data tree creator configured to create a plurality of data trees relating to cell images by classifying the cell images into a plurality of groups each of which includes the cell images that have common classification information (page 10: "Hierarchical Description of Sample Subsets" and pages 13-14, section 3: "Copy gates and statistics to all samples."); a data tree storage configured to store the plurality of data trees created by the data tree creator (page 13: “Drag and Drop Gates and Statistics."); a graph creator configured to create a graph relating to a first data tree that is selected by a user, and having classification information of a bottom layer or a second layer from the bottom layer of the first data tree as a horizontal axis parameter and analysis results of the cell images that are included in the first data tree as a vertical axis parameter (pages 19-22, section 5: "Generate a graphical report of all samples."); and a display controller configured to display the graph created by the graph creator (pages 19-22, section 5: "Generate a graphical report of all samples."), wherein the display controller is configured to display a second data tree that is different from the first data tree and has common horizontal and vertical axis parameters to the first data tree in the plurality of data trees stored in the data tree storage to be selectable by the user, and, when the second data tree is selected by the user, to update the graph by adding the analysis results of the cell images that are included in the second data tree selected by the user to the graph (pages 20-21, section 5.2: "2) Histogram Overlay''). Regarding claim 2, the cell image analysis system according to claim 1, Wilshire further discloses comprising a data tree searcher configured to search for the second data tree in the plurality of data trees stored in the data tree storage, wherein the display controller is configured to display the second data tree searched by the data tree searcher so as to be selectable by the user (pages 13-14, section 3: "Copy gates and statistics to all samples."). Regarding claim 3, the cell image analysis system according to claim 2, Wilshire further discloses wherein the data tree searcher is configured to be able to search for the second data tree in the plurality of data trees stored in the data tree storage with at least one of a project and a cultivation condition relating to cell cultivation being specified as a search criterion; and the display controller is configured to display the second data tree searched by the data tree searcher with the search criterion being specified to be selectable by the user (pages 13-14, section 3: "Copy gates and statistics to all samples."). Regarding claim 4, the cell image analysis system according to claim 3, Wilshire further discloses wherein the data tree searcher is configured to be able to search for the second data tree in the plurality of data trees stored in the data tree storage with a cultivation condition that is common to the first data tree being specified as the search criterion; and the display controller is configured to display the second data tree, which corresponds to the cultivation condition that is common to the first data tree, searched by the data tree searcher with the cultivation condition that is common to the first data tree being specified as the search criterion (pages 13-14, section 3: "Copy gates and statistics to all samples."). Regarding claim 5, the cell image analysis system according to claim 1, Wilshire further discloses wherein the display controller is configured to update the graph by adding the analysis results of the cell images that are included in the second data tree selected by the user in a color different from the analysis results of the cell images that are included in the first data tree to the graph (pages 20-21, section 5.2: "2) Histogram Overlay'', second paragraph). Regarding claim 6, the cell image analysis system according to claim 1, Wilshire further discloses wherein the display controller is configured to update the graph, when the user provides an instruction to delete the analysis results that are included in the second data tree and have been added to the graph, by deleting the analysis results of the cell images that are included in the second data tree and have been added to the graph from the graph (page 13, section 3: "Copy gates and statistics to all samples.", second paragraph). Regarding claim 7, the cell image analysis system according to claim 1, Wilshire further discloses wherein the horizontal axis parameter is accessory information on cell cultivation or imaging (pages 6-7: "Graph Options"). Regarding claim 8, the cell image analysis system according to claim 1, Wilshire further discloses wherein the vertical axis parameter corresponds to feature amounts based on the cell images (pages 6-7: "Graph Options"). Regarding claim 9, the cell image analysis system according to claim 1, Wilshire further discloses wherein the data tree is formed as a virtual data tree having a hierarchical structure on a display screen (page 10: "Hierarchical Description of Sample Subsets"). Regarding claim 10, the cell image analysis system according to claim 1, Wilshire further discloses comprising a file output configured to output the cell images that serve as a basis for the graph including the added analysis results of the cell images that are included in the second data tree, and the graph that includes the added analysis results of the cell images that are included in the second data tree as a CSV file (page 22: “Drawing Tools” and page 24, third paragraph). Regarding claim 11, the cell image analysis system according to claim 10, Wilshire further discloses wherein the file output is configured to output the CSV file with additional information including information on at least one of a project and a cultivation condition relating to cell cultivation (page 22: “Drawing Tools” and page 24, third paragraph). Regarding claim 12, the cell image analysis system according to claim 1, Wilshire further discloses wherein the display controller is configured to display a third data tree that is different from the first data tree and has a common horizontal axis parameter to the first data tree and a vertical axis parameter different from the first data tree in the plurality of data trees stored in the data tree storage to be selectable by the user, and, when the third data tree is selected by the user, to update the graph by adding the analysis results of the cell images that are included in the third data tree selected by the user to the graph (pages 19-22, section 5: "Generate a graphical report of all samples."). Conclusion The prior art made of record and not relied upon is considered pertinent to applicant's disclosure. Devarajan et al., US 2015/0262396 discloses a method of automatically sharing data between graph elements. Wakui, US 2023/0016958 discloses a cell culture evaluation device. Foncubierta Rodriguez et al., US 2020/0401798 discloses computer-implemented methods are provided for generating a data structure representing tabular information in a scanned image. Any inquiry concerning this communication or earlier communications from the examiner should be directed to VAN D HUYNH whose telephone number is (571)270-1937. The examiner can normally be reached 8AM-6PM. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Stephen R Koziol can be reached at (408) 918-7630. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /VAN D HUYNH/Primary Examiner, Art Unit 2665
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Prosecution Timeline

Apr 05, 2024
Application Filed
Jan 31, 2026
Non-Final Rejection — §102
Mar 31, 2026
Response Filed

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
87%
Grant Probability
99%
With Interview (+24.8%)
2y 4m
Median Time to Grant
Low
PTA Risk
Based on 721 resolved cases by this examiner. Grant probability derived from career allow rate.

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