Prosecution Insights
Last updated: July 17, 2026
Application No. 18/709,760

COMPOUND AS FAK INHIBITOR AND USE THEREOF

Non-Final OA §102§112
Filed
May 13, 2024
Priority
Dec 21, 2021 — CN 202111574916.4 +2 more
Examiner
YOO, SUN JAE
Art Unit
1621
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Wigen Biomedicine Technology (Shanghai) Co. Ltd.
OA Round
1 (Non-Final)
71%
Grant Probability
Favorable
1-2
OA Rounds
6m
Est. Remaining
71%
With Interview

Examiner Intelligence

Grants 71% — above average
71%
Career Allowance Rate
875 granted / 1231 resolved
+11.1% vs TC avg
Minimal +0% lift
Without
With
+0.0%
Interview Lift
resolved cases with interview
Typical timeline
2y 8m
Avg Prosecution
102 currently pending
Career history
1292
Total Applications
across all art units

Statute-Specific Performance

§101
0.7%
-39.3% vs TC avg
§103
19.8%
-20.2% vs TC avg
§102
27.5%
-12.5% vs TC avg
§112
24.6%
-15.4% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1231 resolved cases

Office Action

§102 §112
DETAILED ACTION Notice of Pre-AIA or AIA Status 1. The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Election/Restrictions 2. Applicant’s election without traverse of Group I, and species of compound 89, in the reply filed on May 2, 2026 is acknowledged. 3. Examination followed guidelines provided by MPEP 803.02. The elected species appeared to be novel and nonobvious over the prior art. Therefore, the search and examination was extended. Prior art was found that anticipates the claims with respect to a nonelected species. Thus, the Markush claims were rejected and claims to nonelected species were withdrawn from further consideration. The claims were searched to the extent of the elected species, the nonelected species shown below, and additionally to the full scope of claims 3 and 15. 4. Claims 10-12, 17 and 18 withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to a nonelected subject matter. Election was made without traverse in the reply filed on May 2, 2026. Priority 5. Receipt is acknowledged of certified copies of papers required by 37 CFR 1.55. Information Disclosure Statement 6. The information disclosure statements (dated May 13, 2024 and September 7, 2025) were in compliance with the provisions of 37 CFR 1.97 and 37 CFR 1.98. The statements were considered. Signed copies of form 1449 are enclosed herewith. Claim Objections 7. Claims 3 and 15 objected to as being dependent upon a rejected base claim, but would be allowable if rewritten in independent form including all of the limitations of the base claim and any intervening claims. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. 8. A broad range or limitation together with a narrow range or limitation that falls within the broad range or limitation (in the same claim) may be considered indefinite if the resulting claim does not clearly set forth the metes and bounds of the patent protection desired. See MPEP § 2173.05(c). In the present instance, claim 2, 4-7, 9, 13 and 14 recite the broad recitation “L is -CH2- or -O-“, and the claim also recites “preferably -O- “which is the narrower statement of the range/limitation. These types of recitations including the term “preferably” have multiple occurrences in the claims. The claim(s) are considered indefinite because there is a question or doubt as to whether the feature introduced by such narrower language is (a) merely exemplary of the remainder of the claim, and therefore not required, or (b) a required feature of the claims. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. 9. Claim(s) 1, 6-9 and 16 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by RN 213747-32-1 ( PNG media_image1.png 200 596 media_image1.png Greyscale ). The reference has a date of November 5, 1998 which antedate the present claims having an effective filing date of December 14, 2022 and priority claim to foreign applications dated December 21, 2021 and later. The compound corresponds to the present claims in the following manner: m=1; R3=OMe; L=S; R1=R2=H; X=bond; G=heterocycle. 10. Claim(s) 1, 2, 6-9 and 16 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by RN 1227830-04-7 ( PNG media_image2.png 334 626 media_image2.png Greyscale ). The reference has a date of November 5, 1998 which antedate the present claims having an effective filing date of December 14, 2022 and priority claim to foreign applications dated December 21, 2021 and later. The compound corresponds to the present claims in the following manner: L=O; R1=CF3; R2=OMe; R3=H; X=C(O)N; G=methyl piperidine. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to SUN JAE YOO whose telephone number is (571)272-9074. The examiner can normally be reached Mon-Fri 8-5. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /SUN JAE YOO/Primary Examiner, Art Unit 1621
Read full office action

Prosecution Timeline

May 13, 2024
Application Filed
Jun 12, 2026
Non-Final Rejection mailed — §102, §112 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
71%
Grant Probability
71%
With Interview (+0.0%)
2y 8m (~6m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1231 resolved cases by this examiner. Grant probability derived from career allowance rate.

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