Prosecution Insights
Last updated: August 08, 2026
Application No. 18/720,922

TRYPTAMINE COMPOSITIONS AND METHODS

Non-Final OA §102
Filed
Jun 17, 2024
Priority
Jan 14, 2022 — provisional 63/299,599 +2 more
Examiner
RAHMANI, NILOOFAR
Art Unit
Tech Center
Assignee
Cybin Irl Limited
OA Round
1 (Non-Final)
78%
Grant Probability
Favorable
1-2
OA Rounds
0m
Est. Remaining
74%
With Interview

Examiner Intelligence

Grants 78% — above average
78%
Career Allowance Rate
882 granted / 1138 resolved
+17.5% vs TC avg
Minimal -3% lift
Without
With
+-3.1%
Interview Lift
resolved cases with interview
Fast prosecutor
1y 11m
Avg Prosecution
39 currently pending
Career history
1152
Total Applications
across all art units

Statute-Specific Performance

§101
2.7%
-37.3% vs TC avg
§103
14.1%
-25.9% vs TC avg
§102
27.6%
-12.4% vs TC avg
§112
39.2%
-0.8% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1138 resolved cases

Office Action

§102
DETAILED ACTION Claims 1, 7, 9-12, 16, 21-29, 32, 36, 54-63 are pending in the instant application. Applicant’s election of (I), claims 1, 7, 9-12, 16, 21-29, 32, 36 in the reply filed on 07/13/2026 is acknowledged. Because applicant did not distinctly and specifically point out the supposed errors in the restriction requirement, the election has been treated as an election without traverse (MPEP § 818.01(a)). The requirement is still deemed proper and is therefore made FINAL. Claims 1,7,9-12,16,21-29,32,36 are examined. Claims 54-63 are withdrawn per 37 CFR 1.142(b). 2. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. (a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention. Claims 1,7,9-12,16,21, 23, 25, 27-29,32,36 are rejected under 35 U.S.C. 102(a)(2) as being anticipated by Palfreyman et al., US 20240366655. Palfreyman et al. discloses the instant claimed compound, which from the STN search is PNG media_image1.png 250 406 media_image1.png Greyscale , which anticipates the instant compounds. Therefore, the instant claims are anticipated by Palfreyman et al. Claims 1,7,9-12,16,21, 23, 25, 27-29,32,36 are rejected under 35 U.S.C. 102(a)(2) as being anticipated by Slassi et al., US 20240166599. Slassi et al. discloses the instant claimed compound, which from the STN search is PNG media_image2.png 514 522 media_image2.png Greyscale , which anticipates the instant compounds. Therefore, the instant claims are anticipated by Slassi et al. Claims 1,7,9-12,16,21, 23, 25, 27-29,32,36 are rejected under 35 U.S.C. 102(a)(2) as being anticipated by Rands et al., US 11773062. Rands et al. discloses the instant claimed compound, which from the STN search is PNG media_image3.png 240 436 media_image3.png Greyscale , which anticipates the instant compounds. Therefore, the instant claims are anticipated by Rands et al. Claims 1,7,9-12,16,21, 23, 25, 27-29,32,36 are rejected under 35 U.S.C. 102(a)(2) as being anticipated by Nivorozhkin et al., US 11242318. Nivorozhkin et al. discloses the instant claimed compound, which from the STN search is PNG media_image4.png 306 526 media_image4.png Greyscale PNG media_image5.png 458 588 media_image5.png Greyscale , which anticipates the instant compounds. Therefore, the instant claims are anticipated by Nivorozhkin et al. Claims 1,7,9-12,16,21, 23, 25, 27-29,32,36 are rejected under 35 U.S.C. 102(a)(2) as being anticipated by Rands et al., US 12042564. Rands et al. discloses the instant claimed compound, which from the STN search is PNG media_image6.png 68 566 media_image6.png Greyscale PNG media_image7.png 796 706 media_image7.png Greyscale , which anticipates the instant compounds. Therefore, the instant claims are anticipated by Rands et al. Claims 1,7,9-12,16,21, 23, 25, 27-29,32,36 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Morris et al., Journal of Labelled Compounds and Radiopharmaceuticals (1993), 33(6), 455-65. Morris et al. discloses the instant claimed compound, which from the STN search is PNG media_image8.png 58 562 media_image8.png Greyscale PNG media_image9.png 166 250 media_image9.png Greyscale , which anticipates the instant compounds. Therefore, the instant claims are anticipated by Morris et al. Claims 1,7,9-12,16,21, 23, 25, 27-29,32,36 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Barker et al., Biochemical Pharmacology (1982), 31(15), 2513-16. Barker et al. discloses the instant claimed compound, which from the STN search is PNG media_image8.png 58 562 media_image8.png Greyscale PNG media_image9.png 166 250 media_image9.png Greyscale , which anticipates the instant compounds. Therefore, the instant claims are anticipated by Barker et al. Claims 1,7,9-12,16,21, 23, 25, 27-29,32,36 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Beaton et al., Pharmacology, Biochemistry and Behavior (1982), 1695), 811-14. Beaton et al. discloses the instant claimed compound, which from the STN search is PNG media_image8.png 58 562 media_image8.png Greyscale PNG media_image9.png 166 250 media_image9.png Greyscale , which anticipates the instant compounds. Therefore, the instant claims are anticipated by Beaton et al. Claim Objections Claims 22, 24, 26 are objected to as being dependent upon a rejected base claim 1, but would be allowable if rewritten in independent form including all of the limitations of the base claims and any intervening claims. 11. Any inquiry concerning this communication or earlier communications from the examiner should be directed to Niloofar Rahmani whose telephone number is 571-272-4329. The examiner can normally be reached on Monday through Friday from 8:30 am to 5:00 pm. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Renee Claytor, can be reached on 571-272-8394. The fax phone number for the organization where this application or proceeding is assigned is 703-872-9306. Information regarding the status of an application may be obtained from the Patent Application Information Retrieval (PAIR) system. Status information for published applications may be obtained from either Private PAIR or public PAIR. Status information for unpublished applications is available through Private PAIR only. For more information about the PAIR system, see http://pair-direct.uspto.gov. Should you have questions on access to the Private PAIR system, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). /NILOOFAR RAHMANI/ 07/27/2026
Read full office action

Prosecution Timeline

Jun 17, 2024
Application Filed
Jul 30, 2026
Non-Final Rejection mailed — §102 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12696901
PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS
4y 1m to grant Granted Aug 04, 2026
Patent 12698270
ARYL ETHER-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS GLP1R AGONISTS
3y 2m to grant Granted Aug 04, 2026
Patent 12686660
Aza-Substituted Psilocin Analogs And Methods Of Synthesizing The Same
2y 5m to grant Granted Jul 21, 2026
Patent 12678444
SUBSTITUTED PYRAZINE-2-CARBOXAMIDES AS HPK1 INHIBITORS FOR THE TREATMENT OF CANCER
2y 5m to grant Granted Jul 14, 2026
Patent 12673936
ISOINDOLINONE COMPOUNDS, AND USES THEREOF
2y 7m to grant Granted Jul 07, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.
Typically takes 5-10 seconds — AI-generated, attorney review required before filing

Prosecution Projections

1-2
Expected OA Rounds
78%
Grant Probability
74%
With Interview (-3.1%)
1y 11m (~0m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1138 resolved cases by this examiner. Grant probability derived from career allowance rate.

Sign in with your work email

Enter your email to receive a magic link. No password needed.

Personal email addresses (Gmail, Yahoo, etc.) are not accepted.

Free tier: 3 strategy analyses per month