Prosecution Insights
Last updated: October 25, 2026
Application No. 18/722,958

SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME

Non-Final OA §102
Filed
Jun 21, 2024
Priority
Dec 21, 2021 — RE 10-2021-0183638 +2 more
Examiner
MOORE, SUSANNA
Art Unit
1624
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Medific Inc.
OA Round
1 (Non-Final)
68%
Grant Probability
Favorable
1-2
OA Rounds
6m
Est. Remaining
99%
With Interview

Examiner Intelligence

Grants 68% — above average
68%
Career Allowance Rate
862 granted / 1268 resolved
+8.0% vs TC avg
Strong +32% interview lift
Without
With
+31.6%
Interview Lift
resolved cases with interview
Typical timeline
2y 11m
Avg Prosecution
71 currently pending
Career history
1348
Total Applications
across all art units

Statute-Specific Performance

§101
1.5%
-38.5% vs TC avg
§103
17.6%
-22.4% vs TC avg
§102
16.4%
-23.6% vs TC avg
§112
40.3%
+0.3% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1268 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . This is the first action on the merits. Election/Restrictions Applicant's election with traverse of Group (I) in the reply filed on July 23, 2026 is acknowledged. Group (I), drawn to compounds of formula (1), substituted thiazolidinediones and compositions thereof, embraced by claims 1-6 was elected by Applicant. The traversal is on the ground(s) that 1) the Examiner is mistaken in holding that the Group I and Group II claims are directed to separate inventions only because the claims do not fall within paragraph (b) of 37 C.F. R. § 1.475; 2) If the compounds of the Group I claims are patentable, it logically follows that any composition containing the patentable Group I compounds must also be both novel and unobvious, and therefore also patentable; and 3) there would be an undue burden in allowing two separate patents to issue on the same allowable subject matter, and with the protections afforded by 35 U.S.C.§ 121 prohibiting a double-patenting rejection, the two patents can be separately owned and subject the public to multiple patent suits by different patentees for the same inventive concepts. This is not persuasive. The Examiner concluded the inventions lacked a shared special technical feature over the art, see the art rejection herein, which is all that is required to break unity of invention. With regards to point 2, indeed, when the product claims are free of the art and allowable, Group (II) may be rejoined, if commensurate in scope with claim 1. Currently, the claims are not commensurate in scope. Lastly, the 35 U.S.C.§ 121 safety harbor would apply for a divisional application when commensurate in scope with the lack of unity, and therefore, a double patenting rejection would not be applicable. Applicant has not pointed to any errors in the Examiner’s analysis of the classification of the different inventions. The requirement is still deemed proper and is therefore made FINAL. Applicant elected the following species, formula 11 in Example 11: PNG media_image1.png 204 480 media_image1.png Greyscale PNG media_image2.png 376 645 media_image2.png Greyscale . Claims 1 and 3-6 read on the elected species. The elected species was not found during the search. Thus, the search was expanded to a group wherein X1 is carbon and Ar1 is PNG media_image3.png 73 141 media_image3.png Greyscale . Claims 1-10 are pending and claims 1 and 3-6 are under examination. Claims 2 and 7-10 are withdrawn based on the species election and the lack of unity. Claim Objections Claims 4 and 6 are objected to as being dependent upon a rejected base claim. In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale or otherwise available to the public before the effective filing date of the claimed invention. (a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention. Claim(s) 1, 3 and 5 is/are rejected under 35 U.S.C. 102(a)(1) and 102(a)(2) as being anticipated by Clary et al. (US 7968560). The reference teaches the following species: PNG media_image4.png 44 816 media_image4.png Greyscale PNG media_image5.png 140 472 media_image5.png Greyscale PNG media_image6.png 647 826 media_image6.png Greyscale PNG media_image7.png 68 384 media_image7.png Greyscale , see column 6, compounds 3 and 4. The R3 variables is defined as alkyl, and the broadest reasonable interpretation of alkyl is substituted and unsubstitued alkyl. Thus, said claims are anticipated. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to SUSANNA MOORE whose telephone number is (571)272-9046. The examiner can normally be reached Monday - Friday, 10:00 am to 7:00 pm. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Jeffrey Murray, can be reached on 571-272-9023. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /SUSANNA MOORE/Primary Examiner, Art Unit 1624
Read full office action

Prosecution Timeline

Jun 21, 2024
Application Filed
Sep 10, 2026
Non-Final Rejection mailed — §102 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
68%
Grant Probability
99%
With Interview (+31.6%)
2y 11m (~6m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1268 resolved cases by this examiner. Grant probability derived from career allowance rate.

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