Prosecution Insights
Last updated: August 17, 2026
Application No. 18/728,770

MINIATURE MULTISPECTRAL FLUORESCENCE IMAGING AND CELL COLLECTION PROBE

Final Rejection §112
Filed
Jul 12, 2024
Priority
Jan 14, 2022 — provisional 63/266,791 +1 more
Examiner
ROY, BAISAKHI
Art Unit
3797
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Arizona Board of Regents on Behalf of the University of Arizona
OA Round
4 (Final)
78%
Grant Probability
Favorable
5-6
OA Rounds
1y 8m
Est. Remaining
96%
With Interview

Examiner Intelligence

Grants 78% — above average
78%
Career Allowance Rate
528 granted / 680 resolved
+7.6% vs TC avg
Strong +19% interview lift
Without
With
+18.6%
Interview Lift
resolved cases with interview
Typical timeline
3y 9m
Avg Prosecution
24 currently pending
Career history
706
Total Applications
across all art units

Statute-Specific Performance

§101
7.6%
-32.4% vs TC avg
§103
53.9%
+13.9% vs TC avg
§102
12.2%
-27.8% vs TC avg
§112
15.6%
-24.4% vs TC avg
Black line = Tech Center average estimate • Based on career data from 680 resolved cases

Office Action

§112
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Response to Arguments In view of the amendments and new added claims, lack of clarity issues has resulted in a 112(b) Rejection set forth below. Upon further consideration of the References, the 103 Rejection has been withdrawn. Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(b): (b) CONCLUSION.—The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the inventor or a joint inventor regards as the invention. The following is a quotation of 35 U.S.C. 112 (pre-AIA ), second paragraph: The specification shall conclude with one or more claims particularly pointing out and distinctly claiming the subject matter which the applicant regards as his invention. Claims 1-6, 8-10, 12-14, 16, 17, 23-27 are rejected under 35 U.S.C. 112(b) or 35 U.S.C. 112 (pre-AIA ), second paragraph, as being indefinite for failing to particularly point out and distinctly claim the subject matter which the inventor or a joint inventor (or for applications subject to pre-AIA 35 U.S.C. 112, the applicant), regards as the invention. Claims 1 and 25 have been amended to the optical fiber spanning between the distal tip and proximal end and removing the limitation “terminates at the distal tip”. Under broadest reasonable interpretation, the fiber spans the housing distal to proximal end and may also be extending from the distal end or extending past the distal end. The claim is not limited to the fiber terminating at the distal end. Looking at the specification, the fibers 419 extend from the proximal end to the distal end and exit at the distal end of the probe 420 [0040]. New claims 26 and 27 recite “optical fiber either terminates at or extends from the distal tip”. It is not clear how the fiber can terminate at the distal end or extend from the distal end as the two options are structurally very different and it is not clear if the claims are directed to two different embodiments of the imaging probe. The specification [0040 and 0041] disclose that the fibers extend to the distal end of the probe and “exit at distal tip 421” [0041]. Does “exit” mean the fiber is extending from the distal end? Paragraph [0052] discloses “fiber spans between the distal tip and a proximal end of the housing and terminates at the distal tip”. Therefore, it is not clear from the claim language in view of the specification, if the fibers end or terminate at the distal tip or extend past the distal tip or is it two different embodiments of the arrangement of the optical fiber where the fiber may terminate at the distal end in one embodiment or extend past the distal end in another embodiment. It is suggested claims 1 and 25 provide clarifying language (in view of the specification and figures) the arrangement of the fiber with respect to the housing and the configuration at the distal end of the housing as to whether the fiber terminates at the distal end or extends past the distal end. An updated search has not resulted in the claimed arrangement of the imaging probe. Conclusion THIS ACTION IS MADE FINAL. Applicant is reminded of the extension of time policy as set forth in 37 CFR 1.136(a). A shortened statutory period for reply to this final action is set to expire THREE MONTHS from the mailing date of this action. In the event a first reply is filed within TWO MONTHS of the mailing date of this final action and the advisory action is not mailed until after the end of the THREE-MONTH shortened statutory period, then the shortened statutory period will expire on the date the advisory action is mailed, and any nonprovisional extension fee (37 CFR 1.17(a)) pursuant to 37 CFR 1.136(a) will be calculated from the mailing date of the advisory action. In no event, however, will the statutory period for reply expire later than SIX MONTHS from the mailing date of this final action. Any inquiry concerning this communication or earlier communications from the examiner should be directed to BAISAKHI ROY whose telephone number is (571)272-7139. The examiner can normally be reached Monday-Friday 7-3 EST. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Christopher Koharski can be reached at 571-272-7230. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. BR /BAISAKHI ROY/Primary Examiner, Art Unit 3797
Read full office action

Prosecution Timeline

Show 4 earlier events
Jan 05, 2026
Response after Non-Final Action
Jan 29, 2026
Request for Continued Examination
Feb 10, 2026
Response after Non-Final Action
Mar 13, 2026
Non-Final Rejection mailed — §112
Jun 08, 2026
Applicant Interview (Telephonic)
Jun 08, 2026
Examiner Interview Summary
Jun 15, 2026
Response Filed
Aug 04, 2026
Final Rejection mailed — §112 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

5-6
Expected OA Rounds
78%
Grant Probability
96%
With Interview (+18.6%)
3y 9m (~1y 8m remaining)
Median Time to Grant
High
PTA Risk
Based on 680 resolved cases by this examiner. Grant probability derived from career allowance rate.

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