Prosecution Insights
Last updated: April 19, 2026
Application No. 18/741,667

METHODS AND SYSTEMS FOR TREATING MUCOSAL DYSFUNCTION AND OTHER MEDICAL CONDITIONS OF A PATIENT

Non-Final OA §102
Filed
Jun 12, 2024
Examiner
GEDEON, BRIAN T
Art Unit
3796
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Fractyl Health Inc.
OA Round
1 (Non-Final)
87%
Grant Probability
Favorable
1-2
OA Rounds
2y 8m
To Grant
94%
With Interview

Examiner Intelligence

Grants 87% — above average
87%
Career Allow Rate
1158 granted / 1327 resolved
+17.3% vs TC avg
Moderate +7% lift
Without
With
+7.0%
Interview Lift
resolved cases with interview
Typical timeline
2y 8m
Avg Prosecution
46 currently pending
Career history
1373
Total Applications
across all art units

Statute-Specific Performance

§101
4.3%
-35.7% vs TC avg
§103
40.2%
+0.2% vs TC avg
§102
23.2%
-16.8% vs TC avg
§112
13.2%
-26.8% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1327 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Priority This application is the national stage entry under 35 USC 371 of PCT/US2002/053531 filed 20 December 2022 which claims the benefit of domestic priority of US Provisional Application nos. 63/344,224, 63/330,437, and 63/292,761 respectively filed 20 May 2022, 13 April 2022, and 22 December 2021. Claim Rejections - 35 USC § 102 In the event the determination of the status of the application as subject to AIA 35 U.S.C. 102 and 103 (or as subject to pre-AIA 35 U.S.C. 102 and 103) is incorrect, any correction of the statutory basis (i.e., changing from AIA to pre-AIA ) for the rejection will not be considered a new ground of rejection if the prior art relied upon, and the rationale supporting the rejection, would be the same under either status. The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claim(s) 1 is/are rejected under 35 U.S.C. 102(a)(1) as being anticipated by Rajagopalan et al. (US Publication no. 2017/0333122). In regard to claim 1, Rajagopalan et al. discloses a method of treating a medical condition of a patient (para 3), the method comprising (referring to figure 2, para 214): selecting a patient with a medical condition (para 214, In Step 510, a patient is selected for treatment); and performing a tissue treatment procedure 570 comprising treating target tissue (para 236), wherein the target tissue comprises one or more segments of the selected patient's intestinal tissue, and wherein the tissue segments comprise duodenal mucosal tissue and/or duodenal submucosal tissue (para 10, 11, and 236 wherein the tissue treated can comprise one or more mucosal layers of the duodenum; treatment includes RF or microwave ablation (para 169)); wherein the method treats a medical condition of the patient selected from the group consisting of: mucosal dysfunction (e.g. Crohn’s disease para 163, celiac disease para 164; para 18, patients with impaired insulin resistance); mucosal hyperplasia; mucosal hypoplasia; duodenal dysfunction, such as duodenal mucosal dysfunction (para 154, configured to counteract duodenal mucosal changes that cause an intestinal hormonal impairment leading to insulin resistance in patients; para 157, a list is provided of other disorders that are considered related to the duodenal mucosal dysfunction or may be improved by treatment of duodenal mucosal tissues) diet-induced intestinal maladaptation; and combinations thereof. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to BRIAN T GEDEON whose telephone number is (571)272-3447. The examiner can normally be reached M-F 8:00 am to 5:30 PM ET. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, David E. Hamaoui can be reached at 571-270-5625. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /BRIAN T GEDEON/Primary Examiner, Art Unit 3796 13 February 2026
Read full office action

Prosecution Timeline

Jun 12, 2024
Application Filed
Feb 14, 2026
Non-Final Rejection — §102 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
87%
Grant Probability
94%
With Interview (+7.0%)
2y 8m
Median Time to Grant
Low
PTA Risk
Based on 1327 resolved cases by this examiner. Grant probability derived from career allow rate.

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