Last updated: October 25, 2026

Application No. 18/746,428

FORMULATIONS OF T-TYPE CALCIUM CHANNEL MODULATORS AND METHODS OF USE THEREOF

Non-Final OA

Filed

Jun 18, 2024

Priority

Jul 11, 2019 — provisional 62/873,022 +5 more

Examiner

CHANDRAKUMAR, NIZAL S

Art Unit

1625

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Praxis Precision Medicines Inc.

OA Round

1 (Non-Final)

Interview Optional

— +18.2% interview lift. Interview already conducted in this application's prosecution history. This examiner has a 73% grant rate with +18.2% interview lift. Since an interview has already been tried, recommend written response with narrowed claims based on precedent claim evolution patterns.

Based on 1788 resolved cases, 2023–2026

Examiner Intelligence

CHANDRAKUMAR, NIZAL S View full profile →

Grants 73% — above average

Career Allowance Rate

1300 granted / 1788 resolved

+12.7% vs TC avg

Strong +18% interview lift

Without

With

+18.2%

Interview Lift

resolved cases with interview

Typical timeline

2y 3m

Avg Prosecution

87 currently pending

Career history

1888

Total Applications

across all art units

Statute-Specific Performance

§101

2.2%

-37.8% vs TC avg

§103

29.1%

-10.9% vs TC avg

§102

11.0%

-29.0% vs TC avg

§112

36.8%

-3.2% vs TC avg

Black line = Tech Center average estimate • Based on career data from 1788 resolved cases

Prosecution Timeline

Jun 18, 2024

Application Filed

Jul 15, 2026

Examiner Interview (Telephonic)

Jul 15, 2026

Examiner Interview Summary

Jul 23, 2026

Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

18/037,101

Patent 12767668

IMIDAZOTHIAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF

3y 5m to grant Granted Oct 20, 2026

18/292,801

Patent 12767644

USE OF 3-ARYLPHTHALIDES AND DERIVATIVES THEREOF AS ANTI-INFLAMMATORY AGENTS

2y 8m to grant Granted Oct 20, 2026

17/515,861

Patent 12758562

SYNTHESIS AND PROCESSING OF POLY(PRO-DRUG) MATERIALS FOR EXTENDED DRUG RELEASE AND USES THEREOF

4y 11m to grant Granted Oct 13, 2026

17/780,127

Patent 12753175

PROCESS FOR THE PREPARATION OF (9S)-2-BROMO-9-(2,3,4-TRIFLUOROPHENYL)-6,7,8,9-TETRAHYDRO-5H-[1,2,4]TRIAZOLO[1,5-A]AZEPINE

4y 4m to grant Granted Oct 06, 2026

18/273,299

Patent 12745772

BIOCIDAL MIXTURES

3y 2m to grant Granted Sep 29, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

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Prosecution Projections

1-2

Expected OA Rounds

73%

Grant Probability

91%

With Interview (+18.2%)

2y 3m (~0m remaining)

Median Time to Grant

Low

PTA Risk

Based on 1788 resolved cases by this examiner. Grant probability derived from career allowance rate.