Prosecution Insights
Last updated: April 19, 2026
Application No. 18/756,852

TISSUE MODIFICATION DEVICES AND METHODS OF USING THE SAME

Non-Final OA §102§103
Filed
Jun 27, 2024
Examiner
TEMPLETON, MARINA DELANEY
Art Unit
3794
Tech Center
3700 — Mechanical Engineering & Manufacturing
Assignee
Trice Medical, Inc.
OA Round
3 (Non-Final)
62%
Grant Probability
Moderate
3-4
OA Rounds
4y 1m
To Grant
99%
With Interview

Examiner Intelligence

Grants 62% of resolved cases
62%
Career Allow Rate
59 granted / 95 resolved
-7.9% vs TC avg
Strong +50% interview lift
Without
With
+49.7%
Interview Lift
resolved cases with interview
Typical timeline
4y 1m
Avg Prosecution
52 currently pending
Career history
147
Total Applications
across all art units

Statute-Specific Performance

§103
49.7%
+9.7% vs TC avg
§102
25.7%
-14.3% vs TC avg
§112
22.0%
-18.0% vs TC avg
Black line = Tech Center average estimate • Based on career data from 95 resolved cases

Office Action

§102 §103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application is being examined under the pre-AIA first to invent provisions. Continued Examination Under 37 CFR 1.114 A request for continued examination under 37 CFR 1.114, including the fee set forth in 37 CFR 1.17(e), was filed in this application after final rejection. Since this application is eligible for continued examination under 37 CFR 1.114, and the fee set forth in 37 CFR 1.17(e) has been timely paid, the finality of the previous Office action has been withdrawn pursuant to 37 CFR 1.114. Applicant's submission filed on November 24th, 2025 has been entered. Response to Amendment The amendment filed November 24th, 2025 has been entered. Claims 1, & 3-14 are amended. Claims 2 & 15-16 are canceled. Claims 1, & 3-14 remain pending. Response to Arguments Applicant’s arguments with respect to claims 1 & 3-14 have been considered but are moot because the new ground of rejection does not rely on any reference applied in the prior rejection of record for any teaching or matter specifically challenged in the argument; as necessitate by amendment. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of pre-AIA 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a) the invention was known or used by others in this country, or patented or described in a printed publication in this or a foreign country, before the invention thereof by the applicant for a patent. Claims 1, 4-6, & 9-14 are rejected under pre-AIA 35 U.S.C. 102(a)(2) as being anticipated by Podmore et al. (US 20070299437 A1), hereinafter “Podmore”. Regarding claim 1, Podmore discloses a tissue modification device comprising: a rigid elongated member having a proximal end and a distal end dimensioned to be passed through a minimally invasive body opening ([0034] & [0036]; Figure 1—element 12); a visualization sensor integrated with the distal end of the rigid elongated member ([0038] & [0039]; Figures 1 & 2—element 28); a tissue modifier integrated with the distal end of the rigid elongated member ([0035]; Figures 1 & 2—element 18); and a controller configured to deliver ultrasound energy to a target tissue at a tissue site via the tissue modifier ([0035], [0037], [0052], & [0056]; Figure 1—element 26; connector 26 couples the device to a control system and an ablation energy delivery system such that the ultrasound energy can be delivered in a controlled manner); wherein the rigid elongated member has a length of 5-20 cm between the proximal end and the distal end ([0011] & [0052]; Podmore discloses that the tissue modifier 18 comprises a length of about 0.43 inch ([0052]; Figures 1-2, 13, & 14—elements 18), and although the drawings are not to scale it would appear that based on the proportion of the ultrasound transducer to the rigid elongated member 12, the rigid elongated member 12 would comprise a length of 5-20 cm; further Podmore discloses in [0011] that ablation devices for creating transmural lesions have been described in U.S. Pat. No. 6,971,394 to Sliwa et al. ("Sliwa"), which is incorporated by reference, Sliwa discloses in [Col. 11, lines 27-33], [Col. 12, lines 42-61], & [Col. 40, lines 37-63] that the elongated member has a length of 10-30 cm between the proximal end and the distal end). Regarding claim 4, Podmore discloses all of the limitations of claim 1, as described above. Podmore further discloses wherein the controller is configured to deliver the ultrasound energy preferentially to soft tissue ([0040] & [0049]). Regarding claim 5, Podmore discloses all of the limitations of claim 1, as described above. Podmore further discloses wherein the tissue modifier is configured to deflect at an angle from a longitudinal axis passing through the rigid elongated member ([0038]). Regarding claim 6, Podmore discloses all of the limitations of claim 1, as described above. Podmore further discloses further comprising a sensor positioned at the distal end of the rigid elongated member ([0011]; Podmore discloses in [0011] that ablation devices for creating transmural lesions have been described in U.S. Pat. No. 6,971,394 to Sliwa et al. ("Sliwa"), which is incorporated by reference, Sliwa discloses in [Col. 14, lines 22-34] & [Col. 40, lines 36-63] that the device may comprise a sensor (e.g. temperature sensor) positioned at the distal end of the rigid elongated member). Regarding claim 9, Podmore discloses all of the limitations of claim 6, as described above. Podmore further discloses wherein the sensor comprises a physiological sensor configured to collect physiological data ([0011]; Podmore discloses in [0011] that ablation devices for creating transmural lesions have been described in U.S. Pat. No. 6,971,394 to Sliwa et al. ("Sliwa"), which is incorporated by reference, Sliwa discloses in [Col. 14, lines 22-34] & [Col. 40, lines 36-63] that the device may comprise a sensor wherein the sensor comprises a physiological sensor configured to collect physiological data (e.g. temperature sensor)). Regarding claim 10, Podmore discloses all of the limitations of claim 9, as described above. Podmore further discloses wherein the controller is further configured to transmit the physiological data to an image display component, wherein the image display component is configured to provide the physiological data to a user ([0011]; Podmore discloses in [0011] that ablation devices for creating transmural lesions have been described in U.S. Pat. No. 6,971,394 to Sliwa et al. ("Sliwa"), which is incorporated by reference, Sliwa discloses in [Col. 14, lines 22-34], [Col. 26, lines 40-44], & [Col. 40, lines 36-63] that the device may comprise the sensor wherein the sensor comprises the physiological sensor configured to collect physiological data (e.g. temperature sensor), wherein the controller is further configured to transmit the physiological data to an image display component that configured to provide the physiological data to a user (the control system receives data from the sensors and comprises a temperature display)). Regarding claim 11, Podmore discloses all of the limitations of claim 1, as described above. Podmore further discloses an integrated articulation mechanism that imparts steerability to the distal end of the rigid elongated member ([0037]; Figure 1—element 24). Regarding claim 12, Podmore discloses all of the limitations of claim 1, as described above. Podmore further discloses wherein the distal end of the rigid elongated member is rotatable about its longitudinal axis ([0036]-[0038]; Figure 1—elements 12; it is the examiner position that the distal end of the rigid elongated member 12 would be capable of being rotatable about its longitudinal axis if a user rotated the device 10 about its longitudinal axis). Regarding claim 13, Podmore discloses all of the limitations of claim 1, as described above. Podmore further discloses wherein the rigid elongated member further comprises an irrigation lumen configured to provide fluid to the target tissue, the visualization sensor, or both ([0011] & [0037]; Figure 1—element 26; the connector 26 is configured to couple the device to a fluid delivery mechanism; Podmore discloses in [0011] that ablation devices for creating transmural lesions have been described in U.S. Pat. No. 6,971,394 to Sliwa et al. ("Sliwa"), which is incorporated by reference, Sliwa discloses in [Col. 3, lines 53-57], [Col. 13, lines 45-65], [Col. 16, lines 55-58], & [Col. 40, lines 36-63] that the fluid is provided to target tissue; the examiner notes the rest are in the alternative). Regarding claim 14, Podmore discloses all of the limitations of claim 1, as described above. Podmore further discloses wherein the rigid elongated member further comprises an aspiration lumen configured to remove tissue from the tissue site ([0011] & [0037]; Figure 1—element 26; the connector 26 is configured to couple the device to a fluid withdrawal mechanism; Podmore discloses in [0011] that ablation devices for creating transmural lesions have been described in U.S. Pat. No. 6,971,394 to Sliwa et al. ("Sliwa"), which is incorporated by reference, Sliwa discloses in [Col. 3, lines 53-57], [Col. 13, lines 45-65], [Col. 16, lines 55-58], & [Col. 40, lines 36-63] that the fluid withdrawal is configured to remove tissue from the tissue site). Claim Rejections - 35 USC § 103 The following is a quotation of pre-AIA 35 U.S.C. 103(a) which forms the basis for all obviousness rejections set forth in this Office action: (a) A patent may not be obtained though the invention is not identically disclosed or described as set forth in section 102, if the differences between the subject matter sought to be patented and the prior art are such that the subject matter as a whole would have been obvious at the time the invention was made to a person having ordinary skill in the art to which said subject matter pertains. Patentability shall not be negated by the manner in which the invention was made. Claim 3 is rejected under pre-AIA 35 U.S.C. 103(a) as being unpatentable over Podmore in view of Boulais et al. (previously presented-US 20060106281 A1), hereinafter “Boulais”. Regarding claim 3, Podmore discloses all of the limitations of claim 1, as described above. Podmore does not explicitly disclose wherein the visualization sensor further comprises an integrated light source. Boulais teaches a tissue modification device comprising a visualization sensor ([0113]; Figure 8—element 810) and a tissue modifier configured to deliver ultrasound energy to tissue ([0044] & [0114]; Figure 8—element 822), wherein the visualization sensor further comprises an integrated light source ([0113]; Figure 8—element 812). A person of ordinary skill in the art, before the effective filing date of the claimed invention would have been motivated to modify the visualization sensor, as disclosed by Podmore, to include an integrated light source, as taught by Boulais, as both references and the claimed invention are directed toward tissue modification devices comprising integrated visualization sensors. As disclosed by Boulais, the visualization sensor comprises a light source which may be a light emitting diode or a fiber optic in order to illuminate the tissue to be examined ([0003] & [0113]). It would have been obvious to one of ordinary skill in the art, before the effective filing date of the claimed invention, to modify the visualization sensor, as disclosed by Podmore, to include an integrated light source, as taught by Boulais, as such a modification would illuminate the tissue to be examined by the visualization sensor. Claims 6-7 are rejected under pre-AIA 35 U.S.C. 103(a) as being unpatentable over Podmore in view of Hossack et al. (previously presented-US 6045508 A), hereinafter “Hossack”. Regarding claims 6 & 7, Podmore discloses all of the limitations of claim 1, as described above. Podmore does not disclose a sensor positioned at the distal end of the rigid elongated member (claim 6); wherein the sensor comprises an accelerometer (claim 7). Hossack teaches an ultrasonic device for imaging ([Col. 3, lines 28-60]; Figure 1—element 10), comprising a rigid elongated member ([Col. 3, lines 28-51]; Figure 1—element 12), a sensor positioned at the distal end of the rigid elongated member (claim 6); wherein the sensor comprises an accelerometer (claim 7) ([Col. 9, lines 55-63]). A person of ordinary skill in the art, before the effective filing date of the claimed invention, would have been motivated to modify the distal end, as disclosed by Podmore, to include a sensor positioned at the distal end of the rigid elongated member, wherein the sensor comprises an accelerometer, as taught by Hossack, as both references and the claimed invention are directed toward tissue modifiers comprising ultrasonic probes. As disclosed by Hossack, the ultrasonic probe can include an absolute sensor incorporated in its distal end for position or orientation feedback, such as an accelerometer ([Col. 9, lines 55-63]). It would have been obvious to one of ordinary skill in the art, before the effective filing date of the claimed invention, to modify the distal end, as disclosed by Podmore, to include a sensor positioned at the distal end of the rigid elongated member, wherein the sensor comprises an accelerometer, as taught by Hossack, as such a modification would provide for a sensor that provides feedback regarding the position and orientation of the ultrasonic probe within tissue. Claims 6 & 8 are rejected under pre-AIA 35 U.S.C. 103(a) as being unpatentable over Podmore in view of Law et al. (previously presented-US 5469853 A), hereinafter “Law”. Regarding claims 6 & 8, Podmore discloses all of the limitations of claim 1, as described above. Podmore does not disclose a sensor positioned at the distal end of the rigid elongated member (claim 6); wherein the sensor comprises an optical encoder (claim 8). Law teaches a tissue modification device comprising a rigid elongated member comprising a distal end ([Col. 28, line 66 – Col. 29, line 10] & [Col. 29, lines 34-51]; Figure 38—element 402 & 404), and comprising a sensor positioned at the distal end of the rigid elongated member (claim 6); wherein the sensor comprises an optical encoder (claim 8) ([Col. 31, line 49 – Col. 32, line 6]; Figure 45—element 470). A person of ordinary skill in the art, before the effective filing date of the claimed invention, would have been motivated to modify the distal end, as disclosed by Podmore, to include a sensor positioned at the distal end of the rigid elongated member, wherein the sensor comprises an optical encoder, as taught by Law, as both references and the claimed invention are directed toward tissue modifiers comprising ultrasonic probes with bendable distal ends. As disclosed by Law, the distal end of the ultrasonic probe can include an angle sensor, such as an optical encoder, to sense the angle of the bend of the distal end of the ultrasonic probe and provide feedback to assist the surgeon in performing the procedure ([Col. 31, line 49 – Col. 32, line 6]). It would have been obvious to one of ordinary skill in the art, before the effective filing date of the claimed invention, to modify the distal end, as disclosed by Podmore, to include a sensor positioned at the distal end of the rigid elongated member, wherein the sensor comprises an optical encoder, as taught by Law, as such a modification would provide for a sensor that provides feedback to a surgeon regarding the angle of the bend of the distal end of the device to further assist the surgeon in performing the surgical procedure. Conclusion Accordingly, claims 1 & 3-14 are rejected. Any inquiry concerning this communication or earlier communications from the examiner should be directed to MARINA D TEMPLETON whose telephone number is (571)272-7683. The examiner can normally be reached M-F 8:00am to 5:00pm EST. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Joseph Stoklosa can be reached at (571) 272-1213. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /M.D.T./Examiner, Art Unit 3794 /JOSEPH A STOKLOSA/Supervisory Patent Examiner, Art Unit 3794
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Prosecution Timeline

Jun 27, 2024
Application Filed
Jan 03, 2025
Non-Final Rejection — §102, §103
Jul 16, 2025
Response Filed
Aug 20, 2025
Final Rejection — §102, §103
Sep 25, 2025
Interview Requested
Oct 14, 2025
Examiner Interview Summary
Oct 14, 2025
Applicant Interview (Telephonic)
Nov 24, 2025
Request for Continued Examination
Dec 04, 2025
Response after Non-Final Action
Jan 23, 2026
Non-Final Rejection — §102, §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

3-4
Expected OA Rounds
62%
Grant Probability
99%
With Interview (+49.7%)
4y 1m
Median Time to Grant
High
PTA Risk
Based on 95 resolved cases by this examiner. Grant probability derived from career allow rate.

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