Prosecution Insights
Last updated: September 19, 2026
Application No. 18/758,804

SELECTIVE PEPTIDOMIMETIC MODULATORS OF CAV2.2 (N-TYPE) VOLTAGE-GATED CALCIUM CHANNELS AND USES THEREOF

Non-Final OA §102
Filed
Jun 28, 2024
Priority
Jun 30, 2023 — provisional 63/524,386
Examiner
KOSACK, JOSEPH R
Art Unit
Tech Center
Assignee
University of Pittsburgh
OA Round
1 (Non-Final)
75%
Grant Probability
Favorable
1-2
OA Rounds
5m
Est. Remaining
69%
With Interview

Examiner Intelligence

Grants 75% — above average
75%
Career Allowance Rate
970 granted / 1296 resolved
+14.8% vs TC avg
Minimal -6% lift
Without
With
+-6.2%
Interview Lift
resolved cases with interview
Typical timeline
2y 7m
Avg Prosecution
22 currently pending
Career history
1307
Total Applications
across all art units

Statute-Specific Performance

§101
3.1%
-36.9% vs TC avg
§103
27.5%
-12.5% vs TC avg
§102
22.7%
-17.3% vs TC avg
§112
29.8%
-10.2% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1296 resolved cases

Office Action

§102
DETAILED ACTION Claims 1, 3, 5, 6, 8-13, 22, and 25-33 are pending in the present application. Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Election/Restrictions Applicant’s election without traverse of Group I (claims 1, 3, 5, 6, 8, 26, and 27) in the reply filed on July 21, 2026 is acknowledged. Claims 9-13, 22, 25, and 28-33 are withdrawn from further consideration pursuant to 37 CFR 1.142(b) as being drawn to a nonelected invention. The Applicant has made an election of species in the present application of compound CBD3063. As the elected species has been found to be anticipated as described below, the search has been limited to the elected species. As claim 3 does not read on the elected species, claim 3 is withdrawn from further consideration under 37 CFR 1.142(b) as being drawn to a non-elected invention. Priority The claim to priority to 63/524,386 filed on June 30, 2023 is acknowledged in the present application file. Claim Objections Claim 8 is objected to because of the following informalities: there is a double inclusion of a compound. Claim 8 contains the compounds PNG media_image1.png 84 244 media_image1.png Greyscale and PNG media_image2.png 72 258 media_image2.png Greyscale , which are the same compound. Appropriate correction is required. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claims 1, 5, 6, 8, 26, and 27 are rejected under 35 U.S.C. 102(a)(1) as being anticipated by CAS Registry No. 1281060-70-5 (2011). With respect to claims 1, 6, 26, and 27, CAS Registry No. 1281060-70-5 teaches the compound PNG media_image3.png 122 370 media_image3.png Greyscale , which reads on the claims where p is 0, s is 1, X is C(O), R1 is NR3R4, R3 and R4 form a piperidinyl ring substituted by NH-C(O)-Me. With respect to claim 5, R1 is PNG media_image4.png 78 134 media_image4.png Greyscale . With respect to claim 8, the compound is the first compound of claim 8. Conclusion Claims 1, 5, 6, 8, 26, and 27 are rejected. Claim 8 is objected to. Any inquiry concerning this communication or earlier communications from the examiner should be directed to Joseph Kosack whose telephone number is (571)272-5575. The examiner can normally be reached M-F 8:00-4:30. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Patricia Engle can be reached at 571-272-6660. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /JOSEPH R KOSACK/Primary Examiner, Art Unit 3991
Read full office action

Prosecution Timeline

Jun 28, 2024
Application Filed
Sep 04, 2026
Non-Final Rejection mailed — §102 (current)

Precedent Cases

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
75%
Grant Probability
69%
With Interview (-6.2%)
2y 7m (~5m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1296 resolved cases by this examiner. Grant probability derived from career allowance rate.

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