Prosecution Insights
Last updated: July 17, 2026
Application No. 18/762,390

CARDIAC SARCOMERE INHIBITORS

Non-Final OA §102
Filed
Jul 02, 2024
Priority
Jan 19, 2018 — provisional 62/619,643 +4 more
Examiner
AULAKH, CHARANJIT
Art Unit
1621
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Cytokinetics Inc.
OA Round
1 (Non-Final)
81%
Grant Probability
Favorable
1-2
OA Rounds
0m
Est. Remaining
66%
With Interview

Examiner Intelligence

Grants 81% — above average
81%
Career Allowance Rate
1427 granted / 1766 resolved
+20.8% vs TC avg
Minimal -15% lift
Without
With
+-15.3%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 0m
Avg Prosecution
52 currently pending
Career history
1809
Total Applications
across all art units

Statute-Specific Performance

§101
2.2%
-37.8% vs TC avg
§103
18.5%
-21.5% vs TC avg
§102
21.7%
-18.3% vs TC avg
§112
27.9%
-12.1% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1766 resolved cases

Office Action

§102
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . According to a preliminary amendment filed on Oct. 17, 2024, the applicants have canceled claims 1-53 and furthermore, have added new claims 54-59. Claims 54-59 are pending in the application. Claim Rejections - 35 USC § 102 The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action: A person shall be entitled to a patent unless – (a)(1) the claimed invention was patented, described in a printed publication, or in public use, on sale, or otherwise available to the public before the effective filing date of the claimed invention. Claims 54 and 55 are rejected under 35 U.S.C. 102(a) (1) as being clearly anticipated by Powers (US 2006/0173183 A1, cited on applicant’s form 1449). Power discloses multicyclic bis-amide MMP inhibitors. The compound disclosed in example 2106 (see paragraph [700] on page 116 clearly anticipates the instant compound of formula (5-4). Allowable Subject Matter The following is a statement of reasons for the indication of allowable subject matter: Claims 56-59 are allowed since the instant compounds are neither disclosed nor obvious over the prior art. In the prior art, Power (US 2006/1`73183 A1, cited on applicant’s form 1449) discloses 1,2,4- oxadiazole compound in example 2106 (see page 116) which is closely related to instant compound of formula (15-2). However, this compound differs from the compound of formula (15-2) by having 1,2,4-oxadiazole substituted with an oxo group instead of an ethyl group. Furthermore, there is no teaching, suggestion or motivation in the prior art to modify the compound disclosed by Powers to prepare instant compound of formula (15-2). Any inquiry concerning this communication or earlier communications from the examiner should be directed to CHARANJIT AULAKH whose telephone number is (571)272-0678. The examiner can normally be reached Monday-Friday 7:00-3:30. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Clinton A Brooks can be reached at 571-270-7682. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /CHARANJIT AULAKH/ Primary Examiner, Art Unit 1621
Read full office action

Prosecution Timeline

Jul 02, 2024
Application Filed
Jun 03, 2026
Non-Final Rejection mailed — §102 (current)

Precedent Cases

Applications granted by this same examiner with similar technology

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Patent 12667564
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2y 11m to grant Granted Jun 30, 2026
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3y 11m to grant Granted Jun 23, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
81%
Grant Probability
66%
With Interview (-15.3%)
2y 0m (~0m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1766 resolved cases by this examiner. Grant probability derived from career allowance rate.

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