Prosecution Insights
Last updated: April 19, 2026
Application No. 18/765,523

NON-INVASIVE RADIO-FREQUENCY ANALYTE SENSORS, SYSTEMS AND METHODS

Non-Final OA §103
Filed
Jul 08, 2024
Examiner
WENDEROTH, FREDERICK
Art Unit
2852
Tech Center
2800 — Semiconductors & Electrical Systems
Assignee
Know Labs Inc.
OA Round
1 (Non-Final)
93%
Grant Probability
Favorable
1-2
OA Rounds
2y 4m
To Grant
90%
With Interview

Examiner Intelligence

Grants 93% — above average
93%
Career Allow Rate
675 granted / 726 resolved
+25.0% vs TC avg
Minimal -3% lift
Without
With
+-2.8%
Interview Lift
resolved cases with interview
Typical timeline
2y 4m
Avg Prosecution
22 currently pending
Career history
748
Total Applications
across all art units

Statute-Specific Performance

§101
17.8%
-22.2% vs TC avg
§103
60.0%
+20.0% vs TC avg
§102
9.3%
-30.7% vs TC avg
§112
12.0%
-28.0% vs TC avg
Black line = Tech Center average estimate • Based on career data from 726 resolved cases

Office Action

§103
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claim Rejections - 35 USC § 103 The following is a quotation of 35 U.S.C. 103 which forms the basis for all obviousness rejections set forth in this Office action: A patent for a claimed invention may not be obtained, notwithstanding that the claimed invention is not identically disclosed as set forth in section 102, if the differences between the claimed invention and the prior art are such that the claimed invention as a whole would have been obvious before the effective filing date of the claimed invention to a person having ordinary skill in the art to which the claimed invention pertains. Patentability shall not be negated by the manner in which the invention was made. Claim(s) 1, 2 is/are rejected under 35 U.S.C. 103 as being unpatentable over He et al. (US-20140176338-A1) in view of Zeng (CN-109498025-A). Regarding claim 1 He discloses A health monitoring system ([0002]—[0005]), comprising; a device ([0002]); a radio-frequency (RF) analyte detection device that includes at least one transmit antenna and at least one receive antenna ([0005], Fig. 1 & 2), the at least one transmit antenna is positioned and arranged to transmit an RF signal into a user ([0002]), and the at least one receive antenna is positioned and arranged to detect an RF response signal resulting from transmission of the RF signal by the at least one transmit antenna into the user ([0002]—[0005]); a memory connected to and receiving data from the device and the RF analyte detection device ([0005]—[0007]); He does not disclose “A non-invasive device health-monitoring device And MRI machine a controller connected to and controlling the MRI device and the non-invasive RF analyte detection device; a fusion module connected to the memory and that is configured to extract data therein from the MRI device and the non-invasive RF analyte detection device and that is configured to fuse the data; wherein, the MRI device and the non-invasive RF device are controlled using the controller to put data collected by the MRI device and the non-invasive RF device in the memory and then execute the fusion module to fuse the collected data of both the MRI device and the non-invasive RF device”. Zeng, however, teaches A non-invasive device health-monitoring device (¶ 36 under Summary Of Invention) And MRI machine (ABSTRACT) a controller connected to and controlling the MRI device and the non-invasive RF analyte detection device (ABSTRACT, a controller is inherent in an MRI machine); a fusion module connected to the memory and that is configured to extract data therein from the MRI device and the non-invasive RF analyte detection device (¶ or line 36 under Summary Of Invention) and that is configured to fuse the data (¶ or line 36 under Summary Of Invention); wherein, the MRI device and the non-invasive RF device are controlled using the controller to put data collected by the MRI device and the non-invasive RF device in the memory and then execute the fusion module to fuse the collected data of both the MRI device and the non-invasive RF device (¶ 3 under Background Technology). It would have been obvious to one of ordinary skill in the art before the effective filing date of the claimed invention to include the facility of “MRI machine with the non-invasive RF device” as taught by Zeng in the system of He. The justification for this modification would be to monitor health parameters in real-time at an analyte level. Regarding claim 2 He in view of Zeng teach the health monitoring system of claim 1, Zeng, applied to claim 2, further teaches wherein the MRI device and the non-invasive RF analyte detection device are separate from one another (¶ or line 36 under Summary Of The Invention, the optical sensor is physically separate from the MRI machine). Claim(s) 3, 4 is/are rejected under 35 U.S.C. 103 as being unpatentable over He et al. (US-20140176338-A1) in view of Zeng (CN-109498025-A) in view of Eyster (CN-1455245-A). Regarding claim 3 He discloses A health monitoring method ([0002]—[0005]) comprising: a) collecting a first set of data from a target using a real-time, non-invasive radio-frequency (RF) analyte detection device that includes at least one transmit antenna and at least one receive antenna ([0005], Fig. 1 & 2), the at least one transmit antenna is positioned and arranged to transmit an RF signal into a user ([0002]), the at least one transmit antenna is positioned and arranged to transmit an RF signal into the target ([0002]—[0005]), and the at least one receive antenna is positioned and arranged to detect an RF response signal resulting from transmission of the RF signal by the at least one transmit antenna into the target ([0002]—[0005]); He does not disclose “b) collecting a second set of data from the target using an invasive analyte detection device; c) comparing the first set of data from the real-time, non-invasive RF analyte detection device to the second set of data from the invasive analyte detection device; d) calibrating the real-time, non-invasive RF analyte detection device based on the comparison of the first set of data and the second set of data; and e) repeating steps a)-d) until the real-time, non-invasive RF analyte detection device meets a compliance standard”. Zeng, however, teaches b) collecting a second set of data from the target using an invasive analyte detection device (¶ or line 36 under Summary of the Invention); c) comparing the first set of data from the real-time, non-invasive RF analyte detection device to the second set of data from the invasive analyte detection device (¶ or line 36 under Summary of the Invention); He in view of Zeng do not disclose “d) calibrating the real-time, non-invasive RF analyte detection device based on the comparison of the first set of data and the second set of data; and e) repeating steps a)-d) until the real-time, non-invasive RF analyte detection device meets a compliance standard”. Eyster, however, teaches d) calibrating the real-time, non-invasive RF analyte detection device based on the comparison of the first set of data and the second set of data (¶ 8 & 9 under The Background Technology); and e) repeating steps a)-d) until the real-time, non-invasive RF analyte detection device meets a compliance standard (¶ 8 & 9 under The Background Technology) It would have been obvious to one of ordinary skill in the art before the effective filing date of the claimed invention to include the facility of “invasive/non-invasive analyte” as taught by Zeng as well as the “calibration & compliance data” of Eyster in the method of He in view of Zeng. The justification for this modification would be to 1) to monitor health parameters in real-time at an analyte level, and 2) improve the quality of analyte concentration detection. Regarding claim 4 He in view of Zeng teach the method of claim 3, He in view of Zeng do not teach “performing steps d) and e) on a periodic schedule”. Eyster, however, teaches performing steps d) and e) on a periodic schedule (¶ 8 & 9 under The Background Technology). It would have been obvious to one of ordinary skill in the art before the effective filing date of the claimed invention to include the “calibration based on analyte detection until a limit is reached” as taught by Eyster in the method of He in view of Zeng. The justification for this modification would be to improve the quality of analyte concentration detection. Conclusion Any inquiry concerning this communication or earlier communications from the examiner should be directed to FREDERICK WENDEROTH whose telephone number is (571)270-1945. The examiner can normally be reached M-F 7 a.m. - 4 p.m. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicant is encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Walter Lindsay can be reached at 571-272-1674. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000. /WALTER L LINDSAY JR/Supervisory Patent Examiner, Art Unit 2852 /Frederick Wenderoth/ Examiner, Art Unit 2852
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Prosecution Timeline

Jul 08, 2024
Application Filed
Feb 10, 2026
Non-Final Rejection — §103 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
93%
Grant Probability
90%
With Interview (-2.8%)
2y 4m
Median Time to Grant
Low
PTA Risk
Based on 726 resolved cases by this examiner. Grant probability derived from career allow rate.

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