Prosecution Insights
Last updated: July 17, 2026
Application No. 18/820,925

PRODUCTION OF PROTEINS IN GLUTAMINE-FREE CELL CULTURE MEDIA

Non-Final OA
Filed
Aug 30, 2024
Priority
Aug 11, 2009 — provisional 61/232,889 +8 more
Examiner
MOEHLMAN, ANDREW TERRY
Art Unit
1655
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Genentech Inc.
OA Round
1 (Non-Final)
68%
Grant Probability
Favorable
1-2
OA Rounds
1y 4m
Est. Remaining
99%
With Interview

Examiner Intelligence

Grants 68% — above average
68%
Career Allowance Rate
61 granted / 90 resolved
+7.8% vs TC avg
Strong +59% interview lift
Without
With
+59.0%
Interview Lift
resolved cases with interview
Typical timeline
3y 3m
Avg Prosecution
29 currently pending
Career history
129
Total Applications
across all art units

Statute-Specific Performance

§101
7.1%
-32.9% vs TC avg
§103
45.4%
+5.4% vs TC avg
§102
8.8%
-31.2% vs TC avg
§112
14.6%
-25.4% vs TC avg
Black line = Tech Center average estimate • Based on career data from 90 resolved cases

Prosecution Timeline

Aug 30, 2024
Application Filed
May 20, 2026
Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12680072
Mycomaterial Processing in Liquid Medium
3y 12m to grant Granted Jul 14, 2026
Patent 12673977
HETEROLOGOUS PROTEINS WITH AXONEMAL PROTEINS
3y 11m to grant Granted Jul 07, 2026
Patent 12648987
ALKALINE PHOSPHATASE AGENTS FOR TREATMENT OF RADIATION DISORDERS
3y 1m to grant Granted Jun 09, 2026
Patent 12637493
ENGINEERED MCP AND PCP PROTEINS AND SYSTEMS AND METHODS THEREOF
1y 9m to grant Granted May 26, 2026
Patent 12630812
Subtilase Variants And Polynucleotides Encoding Same
5y 0m to grant Granted May 19, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
68%
Grant Probability
99%
With Interview (+59.0%)
3y 3m (~1y 4m remaining)
Median Time to Grant
Low
PTA Risk
Based on 90 resolved cases by this examiner. Grant probability derived from career allowance rate.

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