Last updated: July 05, 2026

Application No. 18/821,462

POLYANION COATED LIPID NANOPARTICLES AND METHODS OF USE THEREOF

Non-Final OA

Filed

Aug 30, 2024

Priority

Aug 31, 2023 — provisional 63/579,827

Examiner

PURDY, KYLE A

Art Unit

1611

Tech Center

1600 — Biotechnology & Organic Chemistry

Assignee

Massachusetts Institute of Technology

OA Round

1 (Non-Final)

This examiner grants 41% of cases after interview

— +37.0% interview lift. A telephonic interview to clarify the technical implementation could significantly improve the outcome.

Based on 984 resolved cases, 2023–2026

Examiner Intelligence

PURDY, KYLE A View full profile →

Grants 41% of resolved cases

Career Allowance Rate

403 granted / 984 resolved

-19.0% vs TC avg

Strong +37% interview lift

Without

With

+37.0%

Interview Lift

resolved cases with interview

Typical timeline

4y 2m

Avg Prosecution

59 currently pending

Career history

1056

Total Applications

across all art units

Statute-Specific Performance

§101

0.4%

-39.6% vs TC avg

§103

76.0%

+36.0% vs TC avg

§102

8.6%

-31.4% vs TC avg

§112

5.6%

-34.4% vs TC avg

Black line = Tech Center average estimate • Based on career data from 984 resolved cases

Prosecution Timeline

Aug 30, 2024

Application Filed

Mar 25, 2026

Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

16/982,240

Patent 12649000

USE OF ALGINATE OLIGOMERS TO ENHANCE THE TRANSLOCATION OF MICRO/NANOPARTICLES ACROSS MUCUS LAYERS

5y 8m to grant Granted Jun 09, 2026

17/309,122

Patent 12648922

Pet Food Compositions, Method of Treating an Inflammatory Condition and Method of Reducing Ciculatpro-Inflammatory Cytokines

5y 1m to grant Granted Jun 09, 2026

17/718,399

Patent 12648900

Hair restructuring association comprising a quaternary ammonium salt and a sulpho-derivative of vegetable fatty acids

4y 1m to grant Granted Jun 09, 2026

16/752,306

Patent 12636412

COATING COMPOSITION FOR SKIN-CONTACTING SURFACE OF ELASTOMERIC ARTICLES AND ARTICLES CONTAINING THE SAME

6y 4m to grant Granted May 26, 2026

18/249,202

Patent 12636331

COMPOSITION FOR PREVENTING OR TREATING LUNG CANCER, COMPRISING A COMPOUND ISOLATED FROM CEPHALOTAXUS EXTRACT AS AN ACTIVE INGREDIENT

3y 1m to grant Granted May 26, 2026

Study what changed to get past this examiner. Based on 5 most recent grants.

Strategy Recommendation AI-generated — please review before filing

Get a prosecution strategy drawn from examiner precedents, rejection analysis, and claim mapping.

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Prosecution Projections

1-2

Expected OA Rounds

41%

Grant Probability

78%

With Interview (+37.0%)

4y 2m (~2y 3m remaining)

Median Time to Grant

Low

PTA Risk

Based on 984 resolved cases by this examiner. Grant probability derived from career allowance rate.