Prosecution Insights
Last updated: October 02, 2026
Application No. 18/872,318

HSD17B13 INHIBITORS

Non-Final OA §112
Filed
Dec 06, 2024
Priority
Jun 09, 2022 — EU 22177977.0 +1 more
Examiner
SAEED, KAMAL A
Art Unit
Tech Center
Assignee
Boehringer Ingelheim International GmbH
OA Round
1 (Non-Final)
84%
Grant Probability
Favorable
1-2
OA Rounds
3m
Est. Remaining
94%
With Interview

Examiner Intelligence

Grants 84% — above average
84%
Career Allowance Rate
1018 granted / 1214 resolved
+23.9% vs TC avg
Moderate +10% lift
Without
With
+9.8%
Interview Lift
resolved cases with interview
Fast prosecutor
2y 0m
Avg Prosecution
32 currently pending
Career history
1227
Total Applications
across all art units

Statute-Specific Performance

§101
2.5%
-37.5% vs TC avg
§103
9.0%
-31.0% vs TC avg
§102
6.9%
-33.1% vs TC avg
§112
16.6%
-23.4% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1214 resolved cases

Office Action

§112
DETAILED ACTION Notice of Pre-AIA or AIA Status The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA . Claims 1- 5, 7-11, 13 and 14 are currently pending in this Application. Priority CONTINUING DATA This application is a 371 of PCT/EP2023/065025 06/06/2023 FOREIGN APPLICATIONS EP 22177977.0 06/09/2022 Claim Rejections - 35 USC § 112 The following is a quotation of 35 U.S.C. 112(d): (d) REFERENCE IN DEPENDENT FORMS.—Subject to subsection (e), a claim in dependent form shall contain a reference to a claim previously set forth and then specify a further limitation of the subject matter claimed. A claim in dependent form shall be construed to incorporate by reference all the limitations of the claim to which it refers. The following is a quotation of pre-AIA 35 U.S.C. 112, fourth paragraph: Subject to the following paragraph [i.e., the fifth paragraph of pre-AIA 35 U.S.C. 112], a claim in dependent form shall contain a reference to a claim previously set forth and then specify a further limitation of the subject matter claimed. A claim in dependent form shall be construed to incorporate by reference all the limitations of the claim to which it refers. Claims 13 and 14 are rejected under 35 U.S.C. 112(d) or pre-AIA 35 U.S.C. 112, 4th paragraph, as being of improper dependent form for failing to further limit the subject matter of the claim upon which it depends, or for failing to include all the limitations of the claim upon which it depends. Claims 13 and 14 are rejected under 35 U.S.C. 112, 4th paragraph, as being of improper dependent form for failing to further limit the subject matter of the claim upon which it depends, or for failing to include all the limitations of the claim upon which it depends. Claim 13 is directed to products of Formula (Ia), PNG media_image1.png 126 190 media_image1.png Greyscale . The claim depends on claim 1, and there is no variable “Y” recited in claim 1 and the variable “Y” is not defined in claim 13. Claim 1, only allows the presence of PNG media_image2.png 157 179 media_image2.png Greyscale Therefore, said claim does not further limit claim 1. Applicants may cancel the claim(s), amend the claim(s) to place the claim(s) in proper dependent form, rewrite the claim(s) in independent form, or present a sufficient showing that the dependent claim(s) complies with the statutory requirements. Claim 14 is directed to products of Formula (Ib), PNG media_image3.png 215 267 media_image3.png Greyscale . The claim depends on claim 1, and variable “Z” recited in claim 1, does not allow the presence of “OH” in that position. Variable “Z” as defined in claim 1, is directed to heterocyclic groups only. Therefore, said claim does not further limit claim 1. Applicants may cancel the claim(s), amend the claim(s) to place the claim(s) in proper dependent form, rewrite the claim(s) in independent form, or present a sufficient showing that the dependent claim(s) complies with the statutory requirements. Allowable Subject Matter The invention of claims 1- 5, and 7-11, are drawn to products of Formula I, PNG media_image4.png 287 289 media_image4.png Greyscale ; process of preparing products of Formula I and method of using products of Formula I. The products of the instant claims are novel and non-obvious over the prior art. The closest prior art is WO 2021/211974 A1 (US equivalent is US Patent Publication No. 20230150940), which teach products of Formula PNG media_image5.png 188 335 media_image5.png Greyscale and their method of preparation. The prior art does not teach the heterocyclic moiety of variable “Z” and the five-membered heterocyclic group attached to the substituted phenyl group as required in the instantly claimed compound according to Formula (I). Furthermore, the prior art does not provide any teaching, suggestion or motivation to modify the prior art invention and arrive at the instantly claimed product according to Formula (I). Therefore, claims 1- 5, and 7-11 are allowable. Telephone Inquiry Any inquiry concerning this communication or earlier communications from the examiner should be directed to KAMAL A SAEED whose telephone number is (571) 272-0705. Examiner interviews are available via telephone, in-person, and video conferencing using a USPTO supplied web-based collaboration tool. To schedule an interview, applicants are encouraged to use the USPTO Automated Interview Request (AIR) at http://www.uspto.gov/interviewpractice. If attempts to reach the examiner by telephone are unsuccessful, the examiner’s supervisor, Adam C Milligan can be reached at (571)270-7674. The fax phone number for the organization where this application or proceeding is assigned is 571-273-8300. Information regarding the status of published or unpublished applications may be obtained from Patent Center. Unpublished application information in Patent Center is available to registered users. To file and manage patent submissions in Patent Center, visit: https://patentcenter.uspto.gov. Visit https://www.uspto.gov/patents/apply/patent-center for more information about Patent Center and https://www.uspto.gov/patents/docx for information about filing in DOCX format. For additional questions, contact the Electronic Business Center (EBC) at 866-217-9197 (toll-free). If you would like assistance from a USPTO Customer Service Representative, call 800-786-9199 (IN USA OR CANADA) or 571-272-1000 /Kamal A Saeed/ Primary Examiner, Art Unit 1626
Read full office action

Prosecution Timeline

Dec 06, 2024
Application Filed
Sep 10, 2026
Non-Final Rejection mailed — §112 (current)

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Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

1-2
Expected OA Rounds
84%
Grant Probability
94%
With Interview (+9.8%)
2y 0m (~3m remaining)
Median Time to Grant
Low
PTA Risk
Based on 1214 resolved cases by this examiner. Grant probability derived from career allowance rate.

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