Notice of Pre-AIA or AIA Status
The present application, filed on or after March 16, 2013, is being examined under the first inventor to file provisions of the AIA .
Claim Rejections - 35 USC § 102
The following is a quotation of the appropriate paragraphs of 35 U.S.C. 102 that form the basis for the rejections under this section made in this Office action:
A person shall be entitled to a patent unless –
(a)(2) the claimed invention was described in a patent issued under section 151, or in an application for patent published or deemed published under section 122(b), in which the patent or application, as the case may be, names another inventor and was effectively filed before the effective filing date of the claimed invention.
Claim 1 is rejected under 35 U.S.C. 102(a)(2) as being anticipated by Moulton et al. (2024/0193767), (hereinafter referred to as “Moulton”).
Regarding claim 1, Moulton discloses utilizing the compartment model to obtain measurement data of a tracer in each ROI according to kinetic parameters and an arterial blood input function of the tracer in each ROI of a biological tissue (Moulton: figures 2-3 and 20; paragraph 0081), repeating this step to change values of each kinetic parameter and a parameter of the arterial blood input function, so as to obtain a large number of samples, wherein each group of samples contains the measurement data of the ROI and the corresponding arterial blood input function (Moulton: figures 2-3; paragraph 0184, 0190, wherein the plurality of data sets are obtained), constructing a physics-informed neural network to solve kinetic parameters of a quantified physiological process in the compartment model (Moulton: paragraph 0043; 0190-0191), and utilizing the measurement data of the samples as labels to train the neural network, and extracting corresponding kinetic parameters from the network parameters after the training and reconstructing kinetic parameter images (Moulton: paragraph 0043; 0190-1091).
Allowable Subject Matter
Claims 2-8 are objected to as being dependent upon a rejected base claim, but would be allowable if rewritten in independent form including all of the limitations of the base claim and any intervening claims.
Conclusion
The prior art made of record and not relied upon is considered pertinent to applicant's disclosure:
20250336063 10/2025 Kundu
20250169782 05/2025 Mirota
20240412070 12/2024 Karpowicz
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/Dave Czekaj/Supervisory Patent Examiner, Art Unit 2487
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