Prosecution Insights
Last updated: October 01, 2026
Application No. 19/460,949

COMPOSITIONS AND METHODS FOR PROGRAMMED DEATH LIGAND RECEPTOR (PD-L1) EXPRESSION

Non-Final OA
Filed
Jan 27, 2026
Priority
Jul 28, 2023 — provisional 63/516,270 +1 more
Examiner
CHONG, KIMBERLY
Art Unit
1636
Tech Center
1600 — Biotechnology & Organic Chemistry
Assignee
Novo Nordisk Inc.
OA Round
2 (Non-Final)
72%
Grant Probability
Favorable
2-3
OA Rounds
1y 10m
Est. Remaining
85%
With Interview

Examiner Intelligence

Grants 72% — above average
72%
Career Allowance Rate
1087 granted / 1501 resolved
+12.4% vs TC avg
Moderate +13% lift
Without
With
+13.0%
Interview Lift
resolved cases with interview
Typical timeline
2y 6m
Avg Prosecution
56 currently pending
Career history
1559
Total Applications
across all art units

Statute-Specific Performance

§101
3.9%
-36.1% vs TC avg
§103
31.1%
-8.9% vs TC avg
§102
17.1%
-22.9% vs TC avg
§112
33.3%
-6.7% vs TC avg
Black line = Tech Center average estimate • Based on career data from 1501 resolved cases

Prosecution Timeline

Jan 27, 2026
Application Filed
Jun 17, 2026
Non-Final Rejection mailed
Aug 18, 2026
Applicant Interview (Telephonic)
Aug 27, 2026
Non-Final Rejection mailed (current)

Precedent Cases

Applications granted by this same examiner with similar technology

Patent 12729378
MODULATING SYNGAP
3y 5m to grant Granted Sep 08, 2026
Patent 12708643
TREATMENT USING CYTOKINE ENCODING RNA
6y 0m to grant Granted Aug 18, 2026
Patent 12709749
ANTISENSE MOLECULES AND METHODS FOR TREATING PATHOLOGIES
4y 0m to grant Granted Aug 18, 2026
Patent 12697386
NUCLEIC ACID ANTIBODY CONSTRUCTS FOR USE AGAINST EBOLA VIRUS
6y 0m to grant Granted Aug 04, 2026
Patent 12673108
CELL-PENETRATING PEPTIDE CONJUGATES AND METHODS OF THEIR USE
1y 4m to grant Granted Jul 07, 2026
Study what changed to get past this examiner. Based on 5 most recent grants.

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Prosecution Projections

2-3
Expected OA Rounds
72%
Grant Probability
85%
With Interview (+13.0%)
2y 6m (~1y 10m remaining)
Median Time to Grant
Moderate
PTA Risk
Based on 1501 resolved cases by this examiner. Grant probability derived from career allowance rate.

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