Prosecution Insights
Last updated: May 29, 2026

Alexion Pharmaceuticals, Inc.

16 pending office actions • 12 art units • 15 examiners • 0 of 16 (0%) have an AI response strategy ready • 12 patents granted in the last 365 days

Portfolio Summary

16
Total Pending OAs
12
Non-Final OAs
4
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 15 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

10
Overdue
0
Due this week
4
Due this month
1
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 15 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (10)Due ≤ 30 days (4)Due ≤ 60 days (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

1
Hard (6%)
5
Medium (31%)
3
Easy (19%)
7
Unknown (44%)

Rejection Statute Mix

BucketCases
§101 only1 (6%)
§103 only5 (31%)
§112 only3 (19%)
No statute on record7 (44%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

16
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

160 h
Manual time on pending OAs
32 h
Time saved (low, 20%)
56 h
Time saved (mid, 35%)
1.4 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
SZPERKA, MICHAEL EDWARD 2 62.5% +37.6%
RONEY, CELESTE A 1 62.3% +18.0%
WORSHAM, JESSICA N 1 56.6% +57.0%
NATARAJAN, MEERA 1 62.2% +16.8%
RAMIREZ, DELIA M 1 65.0% +56.5%
BRISTOL, LYNN ANNE 1 63.7% +39.7%
BERHANE, SELAM 1 61.3% +55.5%
FAN, LYNN Y 1 46.6% +49.1%
SEITZ, ANTHONY JOSEPH 1 68.8% +28.3%
MARCSISIN, ELLEN JEAN 1 32.8% +48.6%

Hard Cases (1)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18219138 ANTI-C5 ANTIBODIES HAVING IMPROVED PHARMACOKINETICS NATARAJAN, MEERA 38d overdue

Interview Candidates (11)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18011807 DOSAGE AND ADMINISTRATION OF ANTI-C5 ANTIBODIES FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) IN PEDIATRIC PATIENTS BERHANE, SELAM 73d overdue
18029525 METHODS OF TREATING DERMATOMYOSITIS BRISTOL, LYNN ANNE 53d overdue
18292042 METHODS OF TREATING COPPER METABOLISM-ASSOCIATED DISEASES OR DISORDERS RONEY, CELESTE A 51d overdue
18219138 ANTI-C5 ANTIBODIES HAVING IMPROVED PHARMACOKINETICS NATARAJAN, MEERA 38d overdue
18018936 DOSAGE AND ADMINISTRATION OF ANTI-C5 ANTIBODIES FOR TREATING HEMATOPOIETIC STEM CELL TRANSPLANT-ASSOCIATED THROMBOTIC MICROANGIOPATHY (HSCT-TMA) SZPERKA, MICHAEL EDWARD 17d overdue
17784025 METHODS OF TREATING PREGNANCY-ASSOCIATED ATYPICAL HEMOLYTIC UREMIC SYNDROME USING AN ANTI-C5 ANTIBODY SZPERKA, MICHAEL EDWARD 8d overdue
18010076 METHODS FOR TESTING ANDEXANET POTENCY FAN, LYNN Y 5d overdue
17924610 CIRCULATING B CELL SUBPOPULATIONS IN INDOLENT B CELL LYMPHOMA SEITZ, ANTHONY JOSEPH 14d

Top Art Units

Art UnitApps
1643 3
1641 3
1612 1
1615 1
1652 1
1675 1
1759 1
1629 1
1677 1
1758 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18292042 METHODS OF TREATING COPPER METABOLISM-ASSOCIATED DISEASES OR DISORDERS RONEY, CELESTE A 1612 Other Non-Final OA 51d overdue Pending Jan 25, 2024
18272308 NOVEL FORMULATION FOR TREATING COPPER METABOLISM-ASSOCIATED DISEASES OR DISORDERS WORSHAM, JESSICA N 1615 §103 Non-Final OA 39d Pending Jul 13, 2023
18219138 ANTI-C5 ANTIBODIES HAVING IMPROVED PHARMACOKINETICS NATARAJAN, MEERA 1643 §101 Non-Final OA 38d overdue Pending Jul 07, 2023
18032973 METHOD OF CONTROLLING TOTAL SIALIC ACID CONTENT (TSAC) DURING MANUFACTURING OF ALKALINE PHOSPHATASE RAMIREZ, DELIA M 1652 Other Final Rejection Pending Apr 20, 2023
18029525 METHODS OF TREATING DERMATOMYOSITIS BRISTOL, LYNN ANNE 1643 Other Non-Final OA 53d overdue Pending Mar 30, 2023
18018936 DOSAGE AND ADMINISTRATION OF ANTI-C5 ANTIBODIES FOR TREATING HEMATOPOIETIC STEM CELL TRANSPLANT-ASSOCIATED THROMBOTIC MICROANGIOPATHY (HSCT-TMA) SZPERKA, MICHAEL EDWARD 1641 Other Non-Final OA 17d overdue Pending Jan 31, 2023
18011807 DOSAGE AND ADMINISTRATION OF ANTI-C5 ANTIBODIES FOR TREATING PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) IN PEDIATRIC PATIENTS BERHANE, SELAM 1675 Other Non-Final OA 73d overdue Pending Dec 20, 2022
18010076 METHODS FOR TESTING ANDEXANET POTENCY FAN, LYNN Y 1759 §103 Final Rejection 5d overdue Pending Dec 13, 2022
17924610 CIRCULATING B CELL SUBPOPULATIONS IN INDOLENT B CELL LYMPHOMA SEITZ, ANTHONY JOSEPH 1629 Other Non-Final OA 14d Pending Nov 10, 2022
17923148 METHOD OF USING EXTRACELLULAR VESICLES TO DETECT COMPLEMENT ACTIVATION, AND USES THEREOF TO ASSESS AND/OR MONITOR TREATMENT OF A COMPLEMENT-MEDIATED DISEASE MARCSISIN, ELLEN JEAN 1677 §112 Non-Final OA 26d Pending Nov 03, 2022
17920499 PROTEIN A CHROMATOGRAPHY PURIFICATION OF AN ANTIBODY HUANG, MICKEY NMN 1758 §103 Final Rejection 14d Pending Oct 21, 2022
17838115 METHOD AND SYSTEM FOR IMPROVED MANAGEMENT OF GENETIC DISEASES MINCHELLA, KAITLYN L 1685 §112 Non-Final OA 59d overdue Pending Jun 10, 2022
17784025 METHODS OF TREATING PREGNANCY-ASSOCIATED ATYPICAL HEMOLYTIC UREMIC SYNDROME USING AN ANTI-C5 ANTIBODY SZPERKA, MICHAEL EDWARD 1641 §103 Non-Final OA 8d overdue Pending Jun 09, 2022
17738131 HIGH CONCENTRATION ANTI-C5 ANTIBODY FORMULATIONS KIM, YUNSOO 1641 Other Non-Final OA 19d Pending May 06, 2022
17641907 METHODS OF MEASURING COPPER CONCENTRATION IN BIOLOGICAL SAMPLES XU, XIAOYUN 1797 §112 Non-Final OA 58d overdue Pending Mar 10, 2022
17630601 METHODS FOR TREATMENT OF REFRACTORY GENERALIZED MYASTHENIA GRAVIS WITH ECULIZUMAB CHATTIN, AMY MARIE 1643 §103 Final Rejection 140d overdue Pending Jan 27, 2022

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