Prosecution Insights
Last updated: October 25, 2026

Epizyme Inc.

Technology area: Biotechnology & Pharmaceuticals

5 pending office actions • 5 art units • 5 examiners • 0 of 5 (0%) have an AI response strategy ready • 1 patents granted in the last 365 days

Analysis

Epizyme Inc. has 5 pending office actions in Biotechnology & Pharmaceuticals. The matters involve 5 distinct examiners and 5 distinct art units, indicating that the portfolio is distributed across separate examination environments.

GEMBEH, SHIRLEY V is the busiest examiner, with 1 pending office action. Counsel should monitor each assignment independently while maintaining coherent positions on recurring technical or claim-scope issues.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

5
Total Pending OAs
5
Non-Final OAs
0
Final Rejections
0
Advisory / Quayle

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

0
Hard (0%)
3
Medium (60%)
2
Easy (40%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§103 only1 (20%)
§112 only1 (20%)
Double-patenting only1 (20%)
Double-patenting + other2 (40%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

5
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

50 h
Manual time on pending OAs
10 h
Time saved (low, 20%)
18 h
Time saved (mid, 35%)
0.4 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
GEMBEH, SHIRLEY V 1 63.1% +33.8%
WEDDINGTON, KEVIN E 1 75.3% +9.8%
OLSON, ANDREA STEFFEL 1 62.4% -11.9%
DEKARSKE, MADELINE MCGUIRE 1 20.0% +50.0%
BASQUILL, SEAN M 1 38.8% +21.7%

Hard Cases (1)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18706071 CRYSTALLINE FORMS OF N-((1R,3S)-3-(4-ACETYLPIPERAZIN-1-YL)CYCLOHEXYL)-4-FLUORO-7-METHYL-1H-INDOLE-2-CARBOXAMIDE DEKARSKE, MADELINE MCGUIRE —

Interview Candidates (3)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 3 ordered by deadline are shown.

App #TitleExaminerDue in
18900199 ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS GEMBEH, SHIRLEY V —
18706071 CRYSTALLINE FORMS OF N-((1R,3S)-3-(4-ACETYLPIPERAZIN-1-YL)CYCLOHEXYL)-4-FLUORO-7-METHYL-1H-INDOLE-2-CARBOXAMIDE DEKARSKE, MADELINE MCGUIRE —
18471734 CRYSTALLINE COMPOUNDS AND METHODS OF MAKING THE SAME BASQUILL, SEAN M —

Top Art Units

Art UnitApps
1615 1
1629 1
1693 1
1622 1
1614 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18900199 ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS GEMBEH, SHIRLEY V 1615 DP Non-Final OA — Pending Sep 27, 2024
18895046 METHOD FOR TREATING CANCER WEDDINGTON, KEVIN E 1629 §112Other Non-Final OA — Pending Sep 24, 2024
18734942 COMBINATION THERAPY FOR TREATING CANCER OLSON, ANDREA STEFFEL 1693 §112DP Non-Final OA — Pending Jun 05, 2024
18706071 CRYSTALLINE FORMS OF N-((1R,3S)-3-(4-ACETYLPIPERAZIN-1-YL)CYCLOHEXYL)-4-FLUORO-7-METHYL-1H-INDOLE-2-CARBOXAMIDE DEKARSKE, MADELINE MCGUIRE 1622 §103DP Non-Final OA — Pending Apr 30, 2024
18471734 CRYSTALLINE COMPOUNDS AND METHODS OF MAKING THE SAME BASQUILL, SEAN M 1614 §103 Non-Final OA — Pending Sep 21, 2023

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Frequently Asked Questions

How many pending USPTO office actions does Epizyme Inc. have?

Epizyme Inc. has 5 pending office actions as of October 2026, spread across 5 art units and 5 examiners.

Which USPTO examiner handles the most Epizyme Inc. applications?

Shirley V Gembeh has the most, with 1 of Epizyme Inc.'s pending office actions.

What technology area are Epizyme Inc.'s patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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