Prosecution Insights
Last updated: October 04, 2026

Epizyme Inc.

Technology area: Biotechnology & Pharmaceuticals

4 pending office actions • 1 art units • 4 examiners • 0 of 4 (0%) have an AI response strategy ready • 1 patents granted in the last 365 days

Analysis

Epizyme Inc. currently faces 4 pending office actions within the Biotechnology & Pharmaceuticals technology area. Interestingly, while there are 4 distinct examiners involved in these cases, they are all concentrated within 1 distinct art unit. This suggests a high degree of technical consistency in the company's current filings, even as the workload is distributed across several different individuals. The concentration in this specific unit may allow for a more unified strategy regarding art-unit-specific precedents.

The busiest examiner, GEMBEH, SHIRLEY V, is assigned 1 busiest examiner pending action. This indicates that the active office actions are evenly distributed, as no single examiner holds more than a single case. For the practitioner, this means that while the 1 distinct art unit provides a consistent technical framework, they must manage the unique styles and requirements of 4 distinct examiners simultaneously. This balance of centralized technical review and decentralized examiner interaction is a key feature of the current portfolio.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

4
Total Pending OAs
4
Non-Final OAs
0
Final Rejections
0
Advisory / Quayle

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

0
Hard (0%)
2
Medium (50%)
2
Easy (50%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§103 only1 (25%)
§112 only1 (25%)
Double-patenting only1 (25%)
Double-patenting + other1 (25%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

1
Life Sciences
25% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
3
Business / Other
75% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

40 h
Manual time on pending OAs
8 h
Time saved (low, 20%)
14 h
Time saved (mid, 35%)
0.3 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
GEMBEH, SHIRLEY V 1 63.2% +34.0%
WEDDINGTON, KEVIN E 1 75.2% +9.8%
DEKARSKE, MADELINE MCGUIRE 1 0.0% +0.0%
BASQUILL, SEAN M 1 38.8% +21.7%

Hard Cases (1)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18706071 CRYSTALLINE FORMS OF N-((1R,3S)-3-(4-ACETYLPIPERAZIN-1-YL)CYCLOHEXYL)-4-FLUORO-7-METHYL-1H-INDOLE-2-CARBOXAMIDE DEKARSKE, MADELINE MCGUIRE —

Interview Candidates (2)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 2 ordered by deadline are shown.

App #TitleExaminerDue in
18900199 ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS GEMBEH, SHIRLEY V —
18471734 CRYSTALLINE COMPOUNDS AND METHODS OF MAKING THE SAME BASQUILL, SEAN M —

Top Art Units

Art UnitApps
1614 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18900199 ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS GEMBEH, SHIRLEY V — DP Non-Final OA — Pending Sep 27, 2024
18895046 METHOD FOR TREATING CANCER WEDDINGTON, KEVIN E — §112Other Non-Final OA — Pending Sep 24, 2024
18706071 CRYSTALLINE FORMS OF N-((1R,3S)-3-(4-ACETYLPIPERAZIN-1-YL)CYCLOHEXYL)-4-FLUORO-7-METHYL-1H-INDOLE-2-CARBOXAMIDE DEKARSKE, MADELINE MCGUIRE — §103DP Non-Final OA — Pending Apr 30, 2024
18471734 CRYSTALLINE COMPOUNDS AND METHODS OF MAKING THE SAME BASQUILL, SEAN M 1614 §103 Non-Final OA — Pending Sep 21, 2023

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