Prosecution Insights
Last updated: October 01, 2026

Fred Hutchinson Cancer Research Center

Technology area: Biotechnology & Pharmaceuticals

23 pending office actions • 11 art units • 21 examiners • 0 of 23 (0%) have an AI response strategy ready • 20 patents granted in the last 365 days

Analysis

Fred Hutchinson Cancer Research Center maintains a patent portfolio in the Biotechnology & Pharmaceuticals technology area, currently navigating 23 pending office actions. These actions are spread across 21 distinct examiners, reflecting a wide-reaching prosecution strategy that engages many different individuals at the patent office. The technical breadth of the portfolio is further evidenced by its presence in 11 distinct art units, which is a significant distribution for a biotechnology-focused entity.

PARISI, JESSICA DANIELLE is the busiest examiner for the organization, currently managing 2 pending office actions. While the portfolio involves 21 distinct examiners, the concentration of 2 pending office actions with PARISI, JESSICA DANIELLE represents a specific point of focus within the larger total of 23 pending office actions. The management of 11 distinct art units suggests that the center's innovations cover a variety of specialized biological and pharmaceutical disciplines. This complexity requires careful attention to the distinct examination styles across the 21 examiners currently reviewing the center's applications.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

23
Total Pending OAs
17
Non-Final OAs
6
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 6 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

2
Overdue
1
Due this week
0
Due this month
1
Due in next 60 days
2
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 6 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (2)Due ≤ 7 days (1)Due ≤ 60 days (1)Due later (2)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

10
Hard (43%)
8
Medium (35%)
5
Easy (22%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other5 (22%)
§103 only1 (4%)
§102 only1 (4%)
§112 only4 (17%)
Double-patenting only1 (4%)
Double-patenting + other6 (26%)
Multi-statute (no §101)5 (22%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

18
Life Sciences
78% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
5
Business / Other
22% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

230 h
Manual time on pending OAs
46 h
Time saved (low, 20%)
80 h
Time saved (mid, 35%)
2.0 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
PARISI, JESSICA DANIELLE 2 75.8% +32.3%
ZHANG, KAIJIANG 2 77.1% +34.4%
COHEN, MICHAEL P 1 58.7% +27.5%
YOO, SUN JAE 1 71.1% +0.3%
PYLA, EVELYN Y 1 55.7% +47.1%
SZPERKA, MICHAEL EDWARD 1 62.9% +36.8%
KONOPKA, CATHERINE ANNE 1 58.1% +65.0%
REDDIG, PETER J 1 57.9% +40.2%
CORNELIUS, CLAIRE ADRIENNE 1 66.7% +0.0%
JOHANSEN, PETER N. 1 59.3% +24.4%

Hard Cases (10)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18458108 EPSTEIN BARR VIRUS VACCINES WANG, RUIXUE 49d overdue
18500706 COMBINATION THERAPIES FOR TREATMENT OF BCMA-RELATED CANCERS AND AUTOIMMUNE DISORDERS REDDIG, PETER J 5d
17412105 COMPOSITIONS AND METHODS FOR ACCURATELY IDENTIFYING MUTATIONS ZHANG, KAIJIANG 65d
18820648 COMPOSITIONS AND METHODS FOR PROVIDING HEMATOPOIETIC FUNCTION PYLA, EVELYN Y —
18707096 T CELL IMMUNOTHERAPY FOR HEMATOLOGIC MALIGNANCIES HAVING AN SF3B1 MUTATION SZPERKA, MICHAEL EDWARD —
18576216 METHOD FOR ANALYZING THE ABILITY OF TARGET NUCLEIC ACID SEQUENCES TO IMPACT GENE EXPRESSION PARISI, JESSICA DANIELLE —
18557406 MOLECULAR SIGNATURES OF LONG-TERM COVID-19 AND TREATMENT THEREOF CORNELIUS, CLAIRE ADRIENNE —
18251871 THERAPEUTIC TARGETING OF MESOTHELIN IN ACUTE MYELOID LEUKEMIA WITH CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY HOWARD, ZACHARY C —

Interview Candidates (10)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18500706 COMBINATION THERAPIES FOR TREATMENT OF BCMA-RELATED CANCERS AND AUTOIMMUNE DISORDERS REDDIG, PETER J 5d
17464341 COMPOSITIONS AND METHODS FOR ACCURATELY IDENTIFYING MUTATIONS ZHANG, KAIJIANG 65d
17412105 COMPOSITIONS AND METHODS FOR ACCURATELY IDENTIFYING MUTATIONS ZHANG, KAIJIANG 65d
19008094 HALOGEN TREATMENT OF HEART ATTACK AND ISCHEMIC INJURY COHEN, MICHAEL P —
17029756 CELL POPULATION ANALYSIS USING SINGLE NUCLEOTIDE POLYMORPHISMS FROM SINGLE CELL TRANSCRIPTOMES PARISI, JESSICA DANIELLE —
18820648 COMPOSITIONS AND METHODS FOR PROVIDING HEMATOPOIETIC FUNCTION PYLA, EVELYN Y —
18707096 T CELL IMMUNOTHERAPY FOR HEMATOLOGIC MALIGNANCIES HAVING AN SF3B1 MUTATION SZPERKA, MICHAEL EDWARD —
18412351 COMPOSITIONS AND METHODS TO PROGRAM THERAPEUTIC CELLS USING TARGETED NUCLEIC ACID NANOCARRIER KONOPKA, CATHERINE ANNE —

Top Art Units

Art UnitApps
1684 3
1658 3
1641 3
1672 2
1621 1
1646 1
1638 1
1642 1
1674 1
1682 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19008094 HALOGEN TREATMENT OF HEART ATTACK AND ISCHEMIC INJURY COHEN, MICHAEL P — §102§103§112DP Non-Final OA — Pending Jan 02, 2025
18797649 COMPOSITIONS, KITS, AND METHODS TO INDUCE ACQUIRED CYTORESISTANCE USING STRESS PROTEIN INDUCERS YOO, SUN JAE 1621 DP Non-Final OA — Pending Aug 08, 2024
17029756 CELL POPULATION ANALYSIS USING SINGLE NUCLEOTIDE POLYMORPHISMS FROM SINGLE CELL TRANSCRIPTOMES PARISI, JESSICA DANIELLE 1684 §103 Final Rejection — Pending Sep 23, 2020
18820648 COMPOSITIONS AND METHODS FOR PROVIDING HEMATOPOIETIC FUNCTION PYLA, EVELYN Y — §103§112 Non-Final OA — Pending Aug 30, 2024
18707096 T CELL IMMUNOTHERAPY FOR HEMATOLOGIC MALIGNANCIES HAVING AN SF3B1 MUTATION SZPERKA, MICHAEL EDWARD — §101§102§112 Non-Final OA — Pending May 02, 2024
18412351 COMPOSITIONS AND METHODS TO PROGRAM THERAPEUTIC CELLS USING TARGETED NUCLEIC ACID NANOCARRIER KONOPKA, CATHERINE ANNE — §112DP Non-Final OA — Pending Jan 12, 2024
18576216 METHOD FOR ANALYZING THE ABILITY OF TARGET NUCLEIC ACID SEQUENCES TO IMPACT GENE EXPRESSION PARISI, JESSICA DANIELLE — §101§103§112 Non-Final OA — Pending Jan 03, 2024
18500706 COMBINATION THERAPIES FOR TREATMENT OF BCMA-RELATED CANCERS AND AUTOIMMUNE DISORDERS REDDIG, PETER J 1646 §101§102§103§112Other Non-Final OA 5d Pending Nov 02, 2023
18557406 MOLECULAR SIGNATURES OF LONG-TERM COVID-19 AND TREATMENT THEREOF CORNELIUS, CLAIRE ADRIENNE 1672 §101§103§112 Non-Final OA — Pending Oct 26, 2023
18288420 Mesothelin-specific T cell Receptors and Methods of Using Same JOHANSEN, PETER N. 1658 §112 Non-Final OA — Pending Oct 26, 2023
18491703 ANTI-FOLATE RECEPTOR CONJUGATE THERAPY FOR CANCER TREATMENT HADDAD, MAHER M 1641 §102§103§112DP Non-Final OA — Pending Oct 20, 2023
18458108 EPSTEIN BARR VIRUS VACCINES WANG, RUIXUE 1672 §103§112 Non-Final OA 49d overdue Pending Aug 29, 2023
18456339 DELTA-LIKE NON-CANONICAL NOTCH LIGAND 1 ACTIVITY MODULATORS AND USES THEREOF KOMATSU, LI N 1658 §112 Non-Final OA — Pending Aug 25, 2023
18262674 TREATMENT FOR HSV-1 USING A MEGANUCLEASE ROGERS, ERIC JASON 1638 §102§103§112DP Non-Final OA — Pending Jul 24, 2023
18350637 IGM-MULTIMERIZED SINGLE-DOMAIN ANTIBODIES THAT BIND ROR1 PRIEST, JESSICA MARIE 1642 §112DP Non-Final OA — Pending Jul 11, 2023
18251871 THERAPEUTIC TARGETING OF MESOTHELIN IN ACUTE MYELOID LEUKEMIA WITH CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY HOWARD, ZACHARY C 1674 §103§112 Final Rejection — Pending May 04, 2023
18310649 KSHV ONCOPROTEIN ANTIGENS AND EPITOPES FOR EXPANDING ANTIGEN-SPECIFIC T CELLS ROONEY, NORA MAUREEN 1641 §112 Final Rejection 42d Pending May 02, 2023
18044289 IMPROVED HIGH EFFICIENCY TARGETED IN SITU GENOME-WIDE PROFILING VANN-OJUEKAIYE, KENDRA RAYCHELL 1682 §103§112 Final Rejection — Pending Mar 07, 2023
18173485 METHODS FOR ENHANCING ANTI-TUMOR ACTIVITY OF EXHAUSTED T CELLS NGUYEN, QUANG 1631 §112 Final Rejection 2d overdue Pending Feb 23, 2023
17464341 COMPOSITIONS AND METHODS FOR ACCURATELY IDENTIFYING MUTATIONS ZHANG, KAIJIANG 1684 §102 Non-Final OA 65d Pending Sep 01, 2021
17412105 COMPOSITIONS AND METHODS FOR ACCURATELY IDENTIFYING MUTATIONS ZHANG, KAIJIANG 1684 §101§102§112 Non-Final OA 65d Pending Aug 25, 2021
17312703 TRANSFERRIN RECEPTOR TARGETING PEPTIDES FISCHER, JOSEPH 1658 §112DP Final Rejection — Pending Jun 10, 2021
17272117 METHODS AND COMPOSITIONS FOR ADOPTIVE T CELL THERAPY INCORPORATING INDUCED NOTCH SIGNALING DIBRINO, MARIANNE 1641 §103§112 Non-Final OA — Pending Feb 26, 2021

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