Prosecution Insights
Last updated: October 25, 2026

Gritstone Bio Inc.

Technology area: Biotechnology & Pharmaceuticals

14 pending office actions • 9 art units • 14 examiners • 0 of 14 (0%) have an AI response strategy ready • 4 patents granted in the last 365 days

Analysis

Gritstone Bio Inc. maintains 14 pending office actions focused in the Biotechnology & Pharmaceuticals sector. The portfolio is handled by 14 distinct examiners, matching the total number of pending actions exactly. This distribution indicates that no single examiner is currently managing multiple active files for the company. These matters are distributed across 9 distinct art units, showing some concentration of technology despite the high number of individual examiners. BARRY A CHESTNUT is the busiest examiner for the company, yet holds only 1 pending office action.

This suggests that the prosecution strategy involves navigating a variety of technical niches within the broader pharmaceutical landscape. For a practitioner, this decentralized examiner base requires a flexible approach to prosecution, as each matter will be subject to the unique tendencies of a different reviewer. The concentration in 9 art units suggests that while the examiners differ, the legal and technical hurdles may be similar across several cases. Managing 14 distinct examiners simultaneously requires significant coordination to ensure that arguments made in one case do not negatively impact others. The presence of 14 pending office actions across such a wide range of examiners highlights the complexity of the company's current patenting efforts.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

14
Total Pending OAs
8
Non-Final OAs
6
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 3 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
0
Due this week
0
Due this month
0
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 3 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

8
Hard (57%)
5
Medium (36%)
1
Easy (7%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other5 (36%)
§103 only2 (14%)
§102 only1 (7%)
§112 only1 (7%)
Double-patenting + other2 (14%)
Multi-statute (no §101)3 (21%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

14
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

140 h
Manual time on pending OAs
28 h
Time saved (low, 20%)
49 h
Time saved (mid, 35%)
1.2 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
CHESTNUT, BARRY A 1 73.9% +6.3%
GODDARD, LAURA B 1 50.8% +13.6%
GRIZER, CASSANDRA SENN 1 70.0% +48.0%
JADHAO, SAMADHAN JAISING 1 46.2% +47.0%
DAHLE, CHUN WU 1 50.2% +51.1%
LEE, HOI YAN NMN 1 37.5% +76.2%
LIPPOLIS, ALEXANDRA ROSE 1 47.2% +63.6%
CHEN, STACY BROWN 1 66.1% +40.4%
LEE, YIE CHIA 1 69.2% +46.6%
VIVLEMORE, TRACY ANN 1 73.0% +6.4%

Hard Cases (8)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
16975823 Neoantigen Identification with Pan-Allele Models BAILEY, STEVEN WILLIAM 45d overdue
18658604 SELF-AMPLIFYING RNA COMPOSITIONS AND METHODS OF USE THEREOF CHESTNUT, BARRY A —
18504497 REDUCING JUNCTION EPITOPE PRESENTATION FOR NEOANTIGENS GODDARD, LAURA B —
18272087 HOMOLOGOUS ADENOVIRAL VACCINATION GRIZER, CASSANDRA SENN —
17817312 HIV ANTIGENS AND MHC COMPLEXES LIPPOLIS, ALEXANDRA ROSE —
17744354 ANTIGEN-BINDING PROTEINS TARGETING SHARED NEOANTIGENS LEE, YIE CHIA —
17581788 NEOANTIGEN IDENTIFICATION USING HOTSPOTS WOITACH, JOSEPH T —
17436367 IDENTIFICATION OF NEOANTIGENS WITH MHC CLASS II MODEL NGUYEN, PETER —

Interview Candidates (8)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
18048407 CAPPING COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF LEE, HOI YAN NMN 31d overdue
18504497 REDUCING JUNCTION EPITOPE PRESENTATION FOR NEOANTIGENS GODDARD, LAURA B —
18272087 HOMOLOGOUS ADENOVIRAL VACCINATION GRIZER, CASSANDRA SENN —
18255539 COMPOSITIONS AND METHODS OF USE THEREOF JADHAO, SAMADHAN JAISING —
18018400 ENGINEERED MULTI-SPECIFIC ANTIBODIES AND RELATED METHODS OF USE AND MANUFACTURE DAHLE, CHUN WU —
17817312 HIV ANTIGENS AND MHC COMPLEXES LIPPOLIS, ALEXANDRA ROSE —
17838114 DURABLE VACCINATION CHEN, STACY BROWN —
17744354 ANTIGEN-BINDING PROTEINS TARGETING SHARED NEOANTIGENS LEE, YIE CHIA —

Top Art Units

Art UnitApps
1672 4
1642 2
1687 2
1641 1
1693 1
1637 1
1638 1
1685 1
1643 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18658604 SELF-AMPLIFYING RNA COMPOSITIONS AND METHODS OF USE THEREOF CHESTNUT, BARRY A 1672 §103§112 Non-Final OA — Pending May 08, 2024
18504497 REDUCING JUNCTION EPITOPE PRESENTATION FOR NEOANTIGENS GODDARD, LAURA B 1642 §101§103§112DP Non-Final OA — Pending Nov 08, 2023
18272087 HOMOLOGOUS ADENOVIRAL VACCINATION GRIZER, CASSANDRA SENN 1672 §103§112 Non-Final OA — Pending Jul 12, 2023
18255539 COMPOSITIONS AND METHODS OF USE THEREOF JADHAO, SAMADHAN JAISING 1672 §102§103§112DP Non-Final OA — Pending Jun 01, 2023
18018400 ENGINEERED MULTI-SPECIFIC ANTIBODIES AND RELATED METHODS OF USE AND MANUFACTURE DAHLE, CHUN WU 1641 §112 Non-Final OA — Pending Jan 27, 2023
18048407 CAPPING COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF LEE, HOI YAN NMN 1693 §103Other Final Rejection 31d overdue Pending Oct 20, 2022
17817312 HIV ANTIGENS AND MHC COMPLEXES LIPPOLIS, ALEXANDRA ROSE 1637 §103§112 Non-Final OA — Pending Aug 03, 2022
17838114 DURABLE VACCINATION CHEN, STACY BROWN 1672 §103§112DP Final Rejection — Pending Jun 10, 2022
17744354 ANTIGEN-BINDING PROTEINS TARGETING SHARED NEOANTIGENS LEE, YIE CHIA 1642 §101§102§103§112 Non-Final OA — Pending May 13, 2022
17736738 SHARED NEOANTIGEN VACCINES VIVLEMORE, TRACY ANN 1638 §102Other Final Rejection 141d overdue Pending May 04, 2022
17581788 NEOANTIGEN IDENTIFICATION USING HOTSPOTS WOITACH, JOSEPH T 1687 §101§112Other Non-Final OA — Pending Jan 21, 2022
17436367 IDENTIFICATION OF NEOANTIGENS WITH MHC CLASS II MODEL NGUYEN, PETER 1685 §101§103DP Final Rejection — Pending Sep 03, 2021
17433817 SELECTION OF T CELL RECEPTORS FAUST, AMBER KATHLEEN 1643 §103 Final Rejection — Pending Aug 25, 2021
16975823 Neoantigen Identification with Pan-Allele Models BAILEY, STEVEN WILLIAM 1687 §101§103§112DP Final Rejection 45d overdue Pending Aug 26, 2020

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Frequently Asked Questions

How many pending USPTO office actions does Gritstone Bio Inc. have?

Gritstone Bio Inc. has 14 pending office actions as of October 2026, spread across 9 art units and 14 examiners.

Which USPTO examiner handles the most Gritstone Bio Inc. applications?

Barry A Chestnut has the most, with 1 of Gritstone Bio Inc.'s pending office actions.

What technology area are Gritstone Bio Inc.'s patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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