Prosecution Insights
Last updated: October 25, 2026

Houston Methodist Hospital

Technology area: Biotechnology & Pharmaceuticals

7 pending office actions • 7 art units • 7 examiners • 0 of 7 (0%) have an AI response strategy ready • 6 patents granted in the last 365 days

Analysis

Houston Methodist Hospital has 7 pending office actions in Biotechnology & Pharmaceuticals. The portfolio involves 7 distinct examiners and 7 distinct art units, indicating complete separation across the recorded examination assignments.

ALLEY, GENEVIEVE S is the busiest examiner, with 1 pending matter. A coordinated docketing process should preserve separate response strategies for each matter.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

7
Total Pending OAs
5
Non-Final OAs
2
Final Rejections
0
Advisory / Quayle

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

3
Hard (43%)
4
Medium (57%)
0
Easy (0%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other1 (14%)
§103 only2 (29%)
§102 only1 (14%)
Double-patenting + other1 (14%)
Multi-statute (no §101)2 (29%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

6
Life Sciences
86% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
1
Mechanical / Eng
14% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

70 h
Manual time on pending OAs
14 h
Time saved (low, 20%)
24 h
Time saved (mid, 35%)
0.6 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
ALLEY, GENEVIEVE S 1 60.5% +48.3%
SHELDEN, BION A 1 22.1% +20.1%
CHESTNUT, BARRY A 1 73.9% +6.3%
BELYAVSKYI, MICHAIL A 1 63.9% +28.0%
NICKOL, GARY B 1 46.6% +33.3%
KIM, YUNSOO 1 66.0% +34.0%
TAKENAKA, RISA 1 26.1% +100.0%

Hard Cases (4)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 4 ordered by deadline are shown.

App #TitleExaminerDue in
18875400 DEVICES AND METHODS OF MAKING AND USE THEREOF ALLEY, GENEVIEVE S —
18794147 SYSTEM AND METHOD FOR AUTOMATICALLY AND CONTINUOUSLY MONITORING MEDICATION DELIVERY TO A PATIENT SHELDEN, BION A —
18683238 METHODS AND COMPOSITIONS FOR VACCINATION AGAINST HETEROSUBTYPIC INFLUENZA VIRUSES USING AN ADENOVIRAL VECTOR LEADING TO ENHANCED T CELL RESPONSE THROUGH AUTOPHAGY CHESTNUT, BARRY A —
16964548 METHODS OF FORMING CARDIOMYOCYES TAKENAKA, RISA —

Interview Candidates (6)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 6 ordered by deadline are shown.

App #TitleExaminerDue in
18875400 DEVICES AND METHODS OF MAKING AND USE THEREOF ALLEY, GENEVIEVE S —
18794147 SYSTEM AND METHOD FOR AUTOMATICALLY AND CONTINUOUSLY MONITORING MEDICATION DELIVERY TO A PATIENT SHELDEN, BION A —
18278736 Regulatory T Cell (Treg) Extracellular Vesicle Compositions and Methods BELYAVSKYI, MICHAIL A —
18212127 ANTIGEN-SPECIFIC T CELL RECEPTORS AND CHIMERIC ANTIGEN RECEPTORS, AND METHODS OF USE IN IMMUNE SIGNALING MODULATION FOR CANCER IMMUNOTHERAPY NICKOL, GARY B —
17292423 REGULATORY T CELL (TREG) COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE KIM, YUNSOO —
16964548 METHODS OF FORMING CARDIOMYOCYES TAKENAKA, RISA —

Top Art Units

Art UnitApps
1617 1
3685 1
1672 1
1644 1
1643 1
1641 1
1600 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18875400 DEVICES AND METHODS OF MAKING AND USE THEREOF ALLEY, GENEVIEVE S 1617 §102§112 Non-Final OA — Pending Dec 16, 2024
18794147 SYSTEM AND METHOD FOR AUTOMATICALLY AND CONTINUOUSLY MONITORING MEDICATION DELIVERY TO A PATIENT SHELDEN, BION A 3685 §101§103§112 Final Rejection — Pending Aug 05, 2024
18683238 METHODS AND COMPOSITIONS FOR VACCINATION AGAINST HETEROSUBTYPIC INFLUENZA VIRUSES USING AN ADENOVIRAL VECTOR LEADING TO ENHANCED T CELL RESPONSE THROUGH AUTOPHAGY CHESTNUT, BARRY A 1672 §102§103§112 Non-Final OA — Pending Feb 12, 2024
18278736 Regulatory T Cell (Treg) Extracellular Vesicle Compositions and Methods BELYAVSKYI, MICHAIL A 1644 §102 Non-Final OA — Pending Aug 24, 2023
18212127 ANTIGEN-SPECIFIC T CELL RECEPTORS AND CHIMERIC ANTIGEN RECEPTORS, AND METHODS OF USE IN IMMUNE SIGNALING MODULATION FOR CANCER IMMUNOTHERAPY NICKOL, GARY B 1643 §102§112DP Non-Final OA — Pending Jun 20, 2023
17292423 REGULATORY T CELL (TREG) COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE KIM, YUNSOO 1641 §103 Non-Final OA — Pending May 07, 2021
16964548 METHODS OF FORMING CARDIOMYOCYES TAKENAKA, RISA 1600 §103 Final Rejection — Pending Jul 23, 2020

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Frequently Asked Questions

How many pending USPTO office actions does Houston Methodist Hospital have?

Houston Methodist Hospital has 7 pending office actions as of October 2026, spread across 7 art units and 7 examiners.

Which USPTO examiner handles the most Houston Methodist Hospital applications?

Genevieve S Alley has the most, with 1 of Houston Methodist Hospital's pending office actions.

What technology area are Houston Methodist Hospital's patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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