Prosecution Insights
Last updated: October 02, 2026

Imbria Pharmaceuticals Inc.

Technology area: Biotechnology & Pharmaceuticals

7 pending office actions • 5 art units • 7 examiners • 0 of 7 (0%) have an AI response strategy ready • 3 patents granted in the last 365 days

Analysis

Imbria Pharmaceuticals Inc. maintains a portfolio with 7 pending office actions in the Biotechnology & Pharmaceuticals technology area. These active matters are distributed among 7 distinct examiners and 5 distinct art units. This high number of examiners relative to the pending actions indicates a wide-ranging examination process where no single examiner holds a majority of the company's active cases. The presence of 7 pending office actions reflects an active engagement with the patent office in the pharmaceutical sector.

The busiest examiner for this portfolio is STANLEY BRAM, who is currently managing 1 pending office action. With 7 distinct examiners each handling a single action, the prosecution workload is highly fragmented across the 5 distinct art units. This structure requires practitioners to adapt to several different examiner styles simultaneously, as each of the 7 pending office actions is being reviewed by a different person. The involvement of 5 distinct art units further suggests that the company's pharmaceutical developments cover a broad spectrum of technical categories within the biotechnology sector. Managing 7 distinct examiners across 5 distinct art units necessitates a highly coordinated strategy to ensure consistency in technical arguments.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

7
Total Pending OAs
5
Non-Final OAs
2
Final Rejections
0
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 3 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

3
Overdue
0
Due this week
0
Due this month
0
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 3 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (3)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

1
Hard (14%)
3
Medium (43%)
2
Easy (29%)
1
Unknown (14%)

Rejection Statute Mix

BucketCases
§103 only1 (14%)
Double-patenting only2 (29%)
Double-patenting + other2 (29%)
Multi-statute (no §101)1 (14%)
No statute on record1 (14%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

6
Life Sciences
86% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
1
Business / Other
14% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

70 h
Manual time on pending OAs
14 h
Time saved (low, 20%)
24 h
Time saved (mid, 35%)
0.6 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
BRAM, STANLEY 1 0.0% +0.0%
TRAN, ERIC 1 70.8% +23.3%
SHIAO, REI TSANG 1 79.8% -33.6%
FETTEROLF, BRANDON J 1 52.0% +17.4%
NESTOR, DONNA MICHELLE 1 56.6% +44.2%
GONZALEZ, LUISALBERTO 1 59.4% +47.2%
NEAGU, IRINA 1 46.8% +57.3%

Hard Cases (2)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 2 ordered by deadline are shown.

App #TitleExaminerDue in
17614826 METHODS OF ALTERING CARDIAC REMODELING USING COMPOUNDS THAT PROMOTE GLUCOSE OXIDATION NESTOR, DONNA MICHELLE 74d overdue
18783819 METHODS OF SYNTHESIZING 2-[4-[(2,3,4-TRIMETHOXYPHENYL)METHYL] PIPERAZIN-1-YL]ETHYL PYRIDINE-3-CARBOXYLATE BRAM, STANLEY —

Interview Candidates (5)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 5 ordered by deadline are shown.

App #TitleExaminerDue in
17359714 MODIFIED RELEASE FORMULATIONS OF MODIFIED FORMS OF TRIMETAZIDINE GONZALEZ, LUISALBERTO 128d overdue
17614826 METHODS OF ALTERING CARDIAC REMODELING USING COMPOUNDS THAT PROMOTE GLUCOSE OXIDATION NESTOR, DONNA MICHELLE 74d overdue
17922890 DOSING METHODS FOR TREATMENT OF CARDIOVASCULAR CONDITIONS FETTEROLF, BRANDON J 53d overdue
18780727 METHODS OF TREATING HEART FAILURE WITH HIBERNATING MYOCARDIUM USING MODIFIED FORMS OF TRIMETAZIDINE TRAN, ERIC —
16365074 COMPOSITIONS AND METHODS FOR INCREASING EFFICIENCY OF CARDIAC METABOLISM NEAGU, IRINA —

Top Art Units

Art UnitApps
1629 2
1691 1
1626 1
1627 1
1624 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18783819 METHODS OF SYNTHESIZING 2-[4-[(2,3,4-TRIMETHOXYPHENYL)METHYL] PIPERAZIN-1-YL]ETHYL PYRIDINE-3-CARBOXYLATE BRAM, STANLEY — §102§103§112DP Non-Final OA — Pending Jul 25, 2024
18780727 METHODS OF TREATING HEART FAILURE WITH HIBERNATING MYOCARDIUM USING MODIFIED FORMS OF TRIMETAZIDINE TRAN, ERIC 1629 Other Non-Final OA — Pending Jul 23, 2024
18624508 METHODS OF TREATING HEART FAILURE WITH REDUCED EJECTION FRACTION USING MODIFIED FORMS OF TRIMETAZIDINE SHIAO, REI TSANG 1691 DP Non-Final OA — Pending Apr 02, 2024
17922890 DOSING METHODS FOR TREATMENT OF CARDIOVASCULAR CONDITIONS FETTEROLF, BRANDON J 1626 DP Non-Final OA 53d overdue Pending Nov 02, 2022
17614826 METHODS OF ALTERING CARDIAC REMODELING USING COMPOUNDS THAT PROMOTE GLUCOSE OXIDATION NESTOR, DONNA MICHELLE 1627 §103§112 Final Rejection 74d overdue Pending Nov 29, 2021
17359714 MODIFIED RELEASE FORMULATIONS OF MODIFIED FORMS OF TRIMETAZIDINE GONZALEZ, LUISALBERTO 1624 §103DP Non-Final OA 128d overdue Pending Jun 28, 2021
16365074 COMPOSITIONS AND METHODS FOR INCREASING EFFICIENCY OF CARDIAC METABOLISM NEAGU, IRINA 1629 §103 Final Rejection — Pending Mar 26, 2019

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