Prosecution Insights
Last updated: October 25, 2026

Institute for Systems Biology

Technology areas: Biotechnology & Pharmaceuticals • Transportation, E-Commerce & Mechanical Systems

4 pending office actions • 4 art units • 4 examiners • 0 of 4 (0%) have an AI response strategy ready

Analysis

Institute for Systems Biology is currently navigating 4 pending office actions in the Biotechnology & Pharmaceuticals technology area. These actions are spread across 4 distinct examiners and 4 distinct art units, showing a distributed prosecution profile.

The busiest examiner, EDWARD B WINSTON III, is responsible for 1 pending office action. This distribution means that each of the pending office actions is being handled by a different examiner, requiring the institute to manage separate technical dialogues simultaneously.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

4
Total Pending OAs
3
Non-Final OAs
1
Final Rejections
0
Advisory / Quayle

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

4
Hard (100%)
0
Medium (0%)
0
Easy (0%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 only1 (25%)
§101 + other3 (75%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

3
Life Sciences
75% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
1
Mechanical / Eng
25% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

40 h
Manual time on pending OAs
8 h
Time saved (low, 20%)
14 h
Time saved (mid, 35%)
0.3 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
WINSTON III, EDWARD B 1 20.0% +31.3%
SWITZER, JULIET CAROLINE 1 42.4% +54.0%
PLAYER, ROBERT AUSTIN 1 13.6% +34.1%
FRUMKIN, JESSE P 1 69.9% +47.7%

Hard Cases (4)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 4 ordered by deadline are shown.

App #TitleExaminerDue in
18511862 OMICS-INFERRED BODY INDEX METHOD AND SYSTEM WINSTON III, EDWARD B —
18284033 COMPOSITIONS AND METHODS FOR DETECTING, PREVENTING, AND TREATING DISTURBED MICROBIOTA-IMMUNE HOMEOSTASIS SWITZER, JULIET CAROLINE —
18168056 DETERMINING VIABILITY AND TREATMENT OF DISEASE AGENTS PLAYER, ROBERT AUSTIN —
18160678 PREDICTING A RECOMMENDED THERAPY FROM GUT COMPOSITIONAL DATA FRUMKIN, JESSE P —

Interview Candidates (4)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 4 ordered by deadline are shown.

App #TitleExaminerDue in
18511862 OMICS-INFERRED BODY INDEX METHOD AND SYSTEM WINSTON III, EDWARD B —
18284033 COMPOSITIONS AND METHODS FOR DETECTING, PREVENTING, AND TREATING DISTURBED MICROBIOTA-IMMUNE HOMEOSTASIS SWITZER, JULIET CAROLINE —
18168056 DETERMINING VIABILITY AND TREATMENT OF DISEASE AGENTS PLAYER, ROBERT AUSTIN —
18160678 PREDICTING A RECOMMENDED THERAPY FROM GUT COMPOSITIONAL DATA FRUMKIN, JESSE P —

Top Art Units

Art UnitApps
3683 1
1682 1
1686 1
1685 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
18511862 OMICS-INFERRED BODY INDEX METHOD AND SYSTEM WINSTON III, EDWARD B 3683 §101 Non-Final OA — Pending Nov 16, 2023
18284033 COMPOSITIONS AND METHODS FOR DETECTING, PREVENTING, AND TREATING DISTURBED MICROBIOTA-IMMUNE HOMEOSTASIS SWITZER, JULIET CAROLINE 1682 §101§103§112 Final Rejection — Pending Sep 25, 2023
18168056 DETERMINING VIABILITY AND TREATMENT OF DISEASE AGENTS PLAYER, ROBERT AUSTIN 1686 §101§103§112 Non-Final OA — Pending Feb 13, 2023
18160678 PREDICTING A RECOMMENDED THERAPY FROM GUT COMPOSITIONAL DATA FRUMKIN, JESSE P 1685 §101§102 Non-Final OA — Pending Jan 27, 2023

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Frequently Asked Questions

How many pending USPTO office actions does Institute for Systems Biology have?

Institute for Systems Biology has 4 pending office actions as of October 2026, spread across 4 art units and 4 examiners.

Which USPTO examiner handles the most Institute for Systems Biology applications?

Edward B Winston III has the most, with 1 of Institute for Systems Biology's pending office actions.

What technology area are Institute for Systems Biology's patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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