Prosecution Insights
Last updated: October 26, 2026

Rein Therapeutics Inc.

Technology area: Biotechnology & Pharmaceuticals

6 pending office actions • 6 art units • 6 examiners • 0 of 6 (0%) have an AI response strategy ready • 1 patents granted in the last 365 days

Analysis

Rein Therapeutics Inc. is currently managing 6 pending office actions within the Biotechnology & Pharmaceuticals technology area. The prosecution landscape is diverse, as these 6 actions are spread across 6 distinct examiners. This ratio of 6 actions to 6 examiners suggests that the company's legal team must adapt to six different sets of examination preferences simultaneously.

Furthermore, the company interfaces with 6 distinct art units, indicating that its biotechnological research spans a wide array of specialized USPTO classifications. Shirley V Gembeh is the busiest examiner for the portfolio, though she is responsible for only 1 pending office action. The presence of 6 distinct art units suggests that the company's intellectual property is not confined to a single biotech niche. With Shirley V Gembeh handling 1 pending office action, the company maintains a balanced workload where no single examiner controls a significant portion of the pending matters.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

6
Total Pending OAs
5
Non-Final OAs
1
Final Rejections
0
Advisory / Quayle

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

2
Hard (33%)
3
Medium (50%)
1
Easy (17%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other1 (17%)
§103 only1 (17%)
Double-patenting only1 (17%)
Double-patenting + other2 (33%)
Multi-statute (no §101)1 (17%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

6
Life Sciences
100% of docket
0
Information Tech
0% of docket
0
Communications
0% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

60 h
Manual time on pending OAs
12 h
Time saved (low, 20%)
21 h
Time saved (mid, 35%)
0.5 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
GEMBEH, SHIRLEY V 1 63.1% +33.8%
VARADARAJ, ARCHANA 1 80.0% +33.3%
ESPINOSA, CLAUDIA EDILMA 1 50.9% +56.1%
LIEB, JEANETTE M 1 79.8% +17.4%
MCCOLLUM, ANDREA K 1 60.2% +33.3%
LEE, JAE W 1 65.6% +38.5%

Quick Wins (1)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18702462 MODIFIED CAVEOLIN-1 PEPTIDES FOR THE TREATMENT OF CHRONIC KIDNEY DISEASE VARADARAJ, ARCHANA —

Hard Cases (2)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 2 ordered by deadline are shown.

App #TitleExaminerDue in
18577028 EPITHELIAL SODIUM CHANNEL (ENAC) INHIBITOR CONJUGATES AND METHODS FOR USE THEREOF ESPINOSA, CLAUDIA EDILMA —
18547931 BIOMARKERS FOR THE TREATMENT OF INTERSTITIAL LUNG DISEASE MCCOLLUM, ANDREA K —

Interview Candidates (6)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 6 ordered by deadline are shown.

App #TitleExaminerDue in
19083757 DRY POWDER FORMULATION OF CAVEOLIN-1 PEPTIDES AND METHODS OF USE THEREOF GEMBEH, SHIRLEY V —
18702462 MODIFIED CAVEOLIN-1 PEPTIDES FOR THE TREATMENT OF CHRONIC KIDNEY DISEASE VARADARAJ, ARCHANA —
18577028 EPITHELIAL SODIUM CHANNEL (ENAC) INHIBITOR CONJUGATES AND METHODS FOR USE THEREOF ESPINOSA, CLAUDIA EDILMA —
18571114 MODIFIED CAVEOLIN-1 PEPTIDES FOR THE TREATMENT OF POST-ACUTE COVID-19 LIEB, JEANETTE M —
18547931 BIOMARKERS FOR THE TREATMENT OF INTERSTITIAL LUNG DISEASE MCCOLLUM, ANDREA K —
18002420 MODIFIED CAVEOLIN-1 PEPTIDES FOR THE TREATMENT OF PATHOGEN-INDUCED LUNG INJURY LEE, JAE W —

Top Art Units

Art UnitApps
1615 1
1658 1
1624 1
1654 1
1674 1
1656 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19083757 DRY POWDER FORMULATION OF CAVEOLIN-1 PEPTIDES AND METHODS OF USE THEREOF GEMBEH, SHIRLEY V 1615 DP Non-Final OA — Pending Mar 19, 2025
18702462 MODIFIED CAVEOLIN-1 PEPTIDES FOR THE TREATMENT OF CHRONIC KIDNEY DISEASE VARADARAJ, ARCHANA 1658 §103§112DP Non-Final OA — Pending Apr 18, 2024
18577028 EPITHELIAL SODIUM CHANNEL (ENAC) INHIBITOR CONJUGATES AND METHODS FOR USE THEREOF ESPINOSA, CLAUDIA EDILMA 1624 §103§112 Non-Final OA — Pending Jan 05, 2024
18571114 MODIFIED CAVEOLIN-1 PEPTIDES FOR THE TREATMENT OF POST-ACUTE COVID-19 LIEB, JEANETTE M 1654 §103§112DP Non-Final OA — Pending Dec 15, 2023
18547931 BIOMARKERS FOR THE TREATMENT OF INTERSTITIAL LUNG DISEASE MCCOLLUM, ANDREA K 1674 §101§102§112 Non-Final OA — Pending Aug 25, 2023
18002420 MODIFIED CAVEOLIN-1 PEPTIDES FOR THE TREATMENT OF PATHOGEN-INDUCED LUNG INJURY LEE, JAE W 1656 §103 Final Rejection — Pending Dec 19, 2022

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Frequently Asked Questions

How many pending USPTO office actions does Rein Therapeutics Inc. have?

Rein Therapeutics Inc. has 6 pending office actions as of October 2026, spread across 6 art units and 6 examiners.

Which USPTO examiner handles the most Rein Therapeutics Inc. applications?

Shirley V Gembeh has the most, with 1 of Rein Therapeutics Inc.'s pending office actions.

What technology area are Rein Therapeutics Inc.'s patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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