Prosecution Insights
Last updated: October 25, 2026

Sanford Burnham Prebys Medical Discovery Institute

Technology area: Biotechnology & Pharmaceuticals

19 pending office actions • 17 art units • 19 examiners • 0 of 19 (0%) have an AI response strategy ready • 10 patents granted in the last 365 days

Analysis

Sanford Burnham Prebys Medical Discovery Institute has 20 pending office actions in Biotechnology & Pharmaceuticals. The matters involve 20 distinct examiners and 17 distinct art units, reflecting extensive distribution across the biotechnology examination landscape.

VAZ, JANICE EZVI is the busiest examiner, with 1 pending matter. No examiner concentration is shown in the data. Effective management will depend on centralized docket control and consistent scientific support, combined with response strategies tailored to the 17 art units.

Written from this page's own data; every figure is computed from USPTO records and verified before publication.

Portfolio Summary

19
Total Pending OAs
10
Non-Final OAs
7
Final Rejections
2
Advisory / Quayle

Response Deadline Pressure

Based on the USPTO statutory response window for each pending office action. 8 of the docket's apps have a known mailing date; the rest are excluded from the tile counts.

6
Overdue
0
Due this week
1
Due this month
1
Due in next 60 days
0
Due later

Deadline Fire Line

Every pending office action with a known statutory deadline, placed on a days-until-due axis. Dots left of Today are overdue; the further right, the more runway. Cases that share a deadline window stack vertically. 8 of the docket's apps have a known mailing date.

-30dToday30d60d90d120d
Overdue (6)Due ≤ 30 days (1)Due ≤ 60 days (1)

Case Difficulty Mix

Difficulty is derived from the rejection statutes on the most recent pending office action. §101-driven and multi-statute cases are graded Hard; §112-only and obviousness-type double-patenting cases are graded Easy; everything else is Medium. "Unknown" means we have not yet parsed a statute for that office action.

8
Hard (42%)
10
Medium (53%)
1
Easy (5%)
0
Unknown (0%)

Rejection Statute Mix

BucketCases
§101 + other2 (11%)
§103 only5 (26%)
§102 only2 (11%)
§112 only1 (5%)
Double-patenting + other3 (16%)
Multi-statute (no §101)6 (32%)

Industry Mix

How the docket's pending cases split across USPTO tech-center bands.

18
Life Sciences
95% of docket
0
Information Tech
0% of docket
1
Communications
5% of docket
0
Semiconductors
0% of docket
0
Mechanical / Eng
0% of docket
0
Business / Other
0% of docket

Time-on-OA Estimate

Manual office-action response work runs about 10 hours per case. The time-saved bands below show what IP Author's prosecution pipeline typically delivers — a conservative 20% on the low end, 35% in the middle, 50% on the high end.

190 h
Manual time on pending OAs
38 h
Time saved (low, 20%)
66 h
Time saved (mid, 35%)
1.7 wks
FTE-weeks freed (mid)

Top Examiners on this docket

ExaminerApps on this docketAllow rateInterview lift
VAZ, JANICE EZVI 1 76.3% +20.3%
SAPKOTA, SURAJ 1 0.0% +0.0%
WILLIS, DOUGLAS M 1 82.4% +19.7%
O DELL, DAVID K 1 57.7% +36.0%
MELCHIOR, JAMES RYLAND 1 62.2% +39.5%
HERNANDEZ, JACKSON J 1 50.7% +39.2%
HILL, GRACELYN MARKHAM 1 50.0% +0.0%
WILSON, MICHAEL C 1 41.5% +17.8%
STEELE, AMBER D 1 58.9% +9.3%
HOWARD, ZACHARY C 1 63.9% +37.7%

Quick Wins (1)

Cases in front of an examiner with an allow rate of 80%+ where the difficulty is Easy or Medium. The top 1 ordered by deadline are shown.

App #TitleExaminerDue in
18710429 INHIBITORS OF THE ONCOGENIC SHP2 PHOSPHATASE AND USES THEREOF WILLIS, DOUGLAS M —

Hard Cases (8)

Multi-statute / §101-driven matters, or cases in front of an examiner with an allow rate under 30%. The top 8 ordered by deadline are shown.

App #TitleExaminerDue in
17827584 COMPOSITIONS AND METHODS FOR TREATING NERVOUS SYSTEM INJURIES BRADLEY, CHRISTINA 103d overdue
17312855 Models and Methods Useful for the Treatment of Serrated Colorectal Cancer HOLTZMAN, KATHERINE ANN 46d overdue
18764707 INHIBITION OF GLUTARYL-COA DEHYDROGENASE FOR THE TREATMENT OF MELANOMA SAPKOTA, SURAJ —
18290749 COMPOSITIONS AND METHODS FOR INHIBITING HUMAN BLOOD PROTEIN VITRONECTIN MELCHIOR, JAMES RYLAND —
18273686 SARS-COV-2 THERAPEUTICS HERNANDEZ, JACKSON J —
18327715 MICROSCOPIC IMAGING AND ANALYSES OF EPIGENETIC LANDSCAPE HILL, GRACELYN MARKHAM —
18325745 METHODS AND COMPOSITIONS FOR HAIR FOLLICLE GENERATION WILSON, MICHAEL C —
17997757 METHODS AND COMPOSITIONS FOR INDUCTION OF ANTITUMOR IMMUNITY STONEBRAKER, ALYSSA RAE —

Interview Candidates (7)

Cases in front of an examiner whose interview lift is 10 percentage points or more — i.e. interviewed cases historically resolve more favorably than non-interviewed ones. The top 7 ordered by deadline are shown.

App #TitleExaminerDue in
18156984 METHODS AND COMPOSITIONS FOR CANCER TREATMENT BY INHIBITION OF FBXO44 HOWARD, ZACHARY C 34d
19002503 MACHINE-LEARNING SYSTEM FOR DIAGNOSING DISORDERS AND DISEASES AND DETERMINING DRUG RESPONSIVENESS VAZ, JANICE EZVI —
18710429 INHIBITORS OF THE ONCOGENIC SHP2 PHOSPHATASE AND USES THEREOF WILLIS, DOUGLAS M —
18696213 INHIBITORS OF SERINE/THREONINE PROTEIN KINASE STK3 OR STK4 AND USES THEREOF O DELL, DAVID K —
18290749 COMPOSITIONS AND METHODS FOR INHIBITING HUMAN BLOOD PROTEIN VITRONECTIN MELCHIOR, JAMES RYLAND —
18273686 SARS-COV-2 THERAPEUTICS HERNANDEZ, JACKSON J —
18325745 METHODS AND COMPOSITIONS FOR HAIR FOLLICLE GENERATION WILSON, MICHAEL C —

Top Art Units

Art UnitApps
1624 2
1621 2
2667 1
1635 1
1644 1
1627 1
1656 1
1638 1
1658 1
1674 1

Pending Office Actions

App #TitleExaminerArt UnitStatutesStatusDue inAIFiled
19002503 MACHINE-LEARNING SYSTEM FOR DIAGNOSING DISORDERS AND DISEASES AND DETERMINING DRUG RESPONSIVENESS VAZ, JANICE EZVI 2667 §112DP Non-Final OA — Pending Dec 26, 2024
18764707 INHIBITION OF GLUTARYL-COA DEHYDROGENASE FOR THE TREATMENT OF MELANOMA SAPKOTA, SURAJ 1635 §102§103§112 Non-Final OA — Pending Jul 05, 2024
18710429 INHIBITORS OF THE ONCOGENIC SHP2 PHOSPHATASE AND USES THEREOF WILLIS, DOUGLAS M 1624 §112 Final Rejection — Pending May 15, 2024
18696213 INHIBITORS OF SERINE/THREONINE PROTEIN KINASE STK3 OR STK4 AND USES THEREOF O DELL, DAVID K 1621 §103 Non-Final OA — Pending Mar 27, 2024
18290749 COMPOSITIONS AND METHODS FOR INHIBITING HUMAN BLOOD PROTEIN VITRONECTIN MELCHIOR, JAMES RYLAND 1644 §103§112 Non-Final OA — Pending Jan 19, 2024
18273686 SARS-COV-2 THERAPEUTICS HERNANDEZ, JACKSON J 1627 §103§112 Non-Final OA — Pending Jul 21, 2023
18327715 MICROSCOPIC IMAGING AND ANALYSES OF EPIGENETIC LANDSCAPE HILL, GRACELYN MARKHAM 1656 §101§102§112 Non-Final OA — Pending Jun 01, 2023
18325745 METHODS AND COMPOSITIONS FOR HAIR FOLLICLE GENERATION WILSON, MICHAEL C 1638 §102§103§112 Final Rejection — Pending May 30, 2023
18172116 COMPOSITIONS AND METHODS FOR TREATING DISEASES STEELE, AMBER D 1658 §103§112DPOther Non-Final OA — Pending Feb 21, 2023
18156984 METHODS AND COMPOSITIONS FOR CANCER TREATMENT BY INHIBITION OF FBXO44 HOWARD, ZACHARY C 1674 §103 Non-Final OA 34d Pending Jan 19, 2023
17928468 ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A YOO, SUN JAE 1621 §102 Final Rejection 26d overdue Pending Nov 29, 2022
17997757 METHODS AND COMPOSITIONS FOR INDUCTION OF ANTITUMOR IMMUNITY STONEBRAKER, ALYSSA RAE 1642 §103§112 Final Rejection — Pending Nov 02, 2022
17906818 COMPOSITIONS AND METHODS FOR TREATING SERRATED COLORECTAL CANCER CLARKE, TRENT R 1651 §103Other Non-Final OA 42d overdue Pending Sep 20, 2022
17799639 INHIBITORS OF ULK1/2 AND METHODS OF USING SAME MCDOWELL, BRIAN E 1624 §102 Non-Final OA 29d Pending Aug 12, 2022
17799641 MONO AND COMBINATION THERAPIES WITH ULK1/2 INHIBITORS LEE, WILLIAM Y 1623 §112DP Non-Final OA 145d overdue Pending Aug 12, 2022
17827584 COMPOSITIONS AND METHODS FOR TREATING NERVOUS SYSTEM INJURIES BRADLEY, CHRISTINA 1654 §101§102§112Other Non-Final OA 103d overdue Pending May 27, 2022
17773775 METABOLIC REPROGRAMMING OF IMMUNE CELLS TO ENHANCE THE EFFICACY OF PROPHYLACTIC AND THERAPEUTIC VACCINES RICCI, CRAIG D 1611 §103 Final Rejection 97d overdue Pending May 02, 2022
17510887 NOVEL BIOMOLECULE CONJUGATES AND USES THEREFOR CESARE, JOSEPH DAVID 1600 §103 Final Rejection — Pending Oct 26, 2021
17312855 Models and Methods Useful for the Treatment of Serrated Colorectal Cancer HOLTZMAN, KATHERINE ANN 1646 §103§112Other Final Rejection 46d overdue Pending Jun 10, 2021

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Frequently Asked Questions

How many pending USPTO office actions does Sanford Burnham Prebys Medical Discovery Institute have?

Sanford Burnham Prebys Medical Discovery Institute has 19 pending office actions as of October 2026, spread across 17 art units and 19 examiners.

Which USPTO examiner handles the most Sanford Burnham Prebys Medical Discovery Institute applications?

Janice Ezvi Vaz has the most, with 1 of Sanford Burnham Prebys Medical Discovery Institute's pending office actions.

What technology area are Sanford Burnham Prebys Medical Discovery Institute's patent applications in?

Mostly Biotechnology & Pharmaceuticals (USPTO Tech Center 1600), based on where its pending office actions are examined.

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